Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

High-fat diet makes mice susceptible to liver injury

A high fat diet may kill regulatory T cells in the liver, allowing steatosis (simple fatty liver) to develop into steatohepatitis (fatty liver with inflammation), according to the results of a new study in the November issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD).

2 Nov 2007

Saint Louis University scientists identify chemical that triggers Parkinson's disease

Researchers at the Saint Louis University School of Medicine have discovered the key brain chemical that causes Parkinson's disease - a breakthrough finding that could pave the way for new, far more effective therapies to treat one of the most common and debilitating neurological disorders.

30 Oct 2007

DIY liver test tells you how damage has been done

According to the manufacturers, a simple DIY test can tell drinkers how much damage has been done to their livers.

30 Oct 2007

Early autism detection

In an attempt to spot autism earlier, the American Academy of Pediatrics has recently recommended that all children be screened for autism twice by age 2 - advice that many St. Louis families already heed thanks to a partnership between Saint Louis University and Parents as Teachers.

29 Oct 2007

Attenuation of NASH by stimulation of free fatty acid metabolism

Medically-complicated obesity is a societal problem that needs to be solved. Liver disease, specifically non-alcoholic steatohepatitis or NASH, is just one of the many complications of increased body weight.

28 Oct 2007

Diffusion-weighted MRI predicts liver fibrosis

Moderate to severe chronic liver disease can be predicted with the use of diffusion-weighted MRI (DWI), according to a recent study conducted by researchers at New York University Medical Center in New York, NY.

24 Oct 2007

NIH and India partner to develop low-cost health-care technologies

The National Institute of Biomedical Imaging and Bioengineering (NIBIB), part of the National Institutes of Health (NIH), and the Department of Biotechnology (DBT) of the Ministry of Science and Technology of the Republic of India, have entered into a bilateral agreement to develop low-cost health-care technologies aimed at the medically underserved.

22 Oct 2007

Over 2 decades experiences shows that ultrasound-guided liver biopsy is the procedure of choice

Liver biopsy is a widely used tool in the investigation of liver diseases. It is invasive and has a mortality risk ranging between 0.01% and 0.17%. A liver biopsy should therefore only be performed in patients who would potentially benefit from it.

16 Oct 2007

Middle class, middle-aged Brits drinking too much booze

The latest figures published this week by the British government have revealed the scale of middle class drinking.

16 Oct 2007

Discovery of protein that plays a key role in the recycling of iron from blood

Scientists working in the only lab at MIT doing hematology research have uncovered a protein that plays a key role in the recycling of iron from blood. Their work, described in the October 11 Journal of Clinical Investigation, could lead to new therapies for certain inherited blood disorders such as beta-thalassemia, a condition that causes chronic anemia.

12 Oct 2007

Discovery of genetic roadblock could lead to novel treatments for type 2 diabetes

A team of Mount Sinai Hospital researchers has found that a “genetic roadblock” identified in a recent study could pave the way toward novel treatments for type 2 diabetes.

3 Oct 2007

Noninvasive tests for cirrhosis may help to avoid liver biopsy

Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology.

2 Oct 2007

Rapamycin and Gleevec reverses effects of portal hypertension in rats

A combined treatment with rapamycin and Gleevec might reverse the effects of portal hypertension in patients with chronic liver disease, according to the results of a new study on rats.

2 Oct 2007

Majority of Europeans with hepatitis C remain undiagnosed

A report by the Eurasian Harm Reduction Network (EHRN highlights the significant inconsistencies that exist in hepatitis C (HCV) diagnosis and treatment across Europe and beyond. In recognition of World Hepatitis Awareness Day, patient groups around the globe are united in their call for action.

1 Oct 2007

High GI diet's make fatty liver epidemic a very real threat

According to a recent study, following a high Glycemic Index (GI) diet may increase a persons risk of fatty liver disease.

24 Sep 2007

Diets rich in rapidly-digested carbohydrates may cause fatty liver

Diets rich in rapidly-digested carbohydrates not only expand waistlines, but may also cause fatty liver, a condition that can lead to liver failure and death, finds a new study in mice.

21 Sep 2007

ACTOS associated with reduced risk of heart attack and stroke in patients with type 2 diabetes

Results presented at the 43rd Annual Meeting of the European Association for the Study of Diabetes demonstrate the ability of ACTOS (pioglitazone HCl) to reduce the risk of ischemic cardiovascular disease in patients with type 2 diabetes.

20 Sep 2007

Organ transplantation for HIV-positive patients

Not long ago, organ transplantation was not considered an option for HIV infected patients.

17 Sep 2007

New understanding of tropical disease schistosomiasis

Researchers have provided new details about the inner workings of a parasitic worm that causes a tropical disease called schistosomiasis, which leads to itchy skin, fever, chills, muscle aches, and liver disease that, in some cases, can be fatal.

13 Sep 2007

First-degree relatives of patients with primary biliary cirrhosis more likely to have biomarkers of the disease

Armed with this new information, physicians could screen and assess first-degree relatives of PBC patients with a simple blood test, enabling them to diagnose and treat more patients before the disease causes irreversible liver damage. These findings were published in this month's issue of Hepatology.

11 Sep 2007