Liver Disease News and Research

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The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

TGen and ASU partner with Phoenix Children’s and Cincinnati Children’s to better understand NAFLD

The prevalence of nonalcoholic Fatty Liver Disease, NAFLD, is rising in American children, with kids of Latino ancestry being hit disproportionately hard by the disease.

28 Sep 2022

Selectively targeting iGPX4 may be a promising therapeutic strategy for metabolic-associated fatty liver disease

This new article publication from Acta Pharmaceutica Sinica B, discusses targeting a novel inducible GPX4 alternative isoform to alleviate ferroptosis and treat metabolic-associated fatty liver disease.

26 Sep 2022

UTHSC professor receives $5 million to explore the gut as therapeutic target for treating disease

Radhakrishna Rao, PhD, vice-chair and professor in the Department of Physiology at the University of Tennessee Health Science Center (UTHSC), has received two large national awards totaling $5 million for separate studies involving the gut as a therapeutic target for treating disease.

26 Sep 2022

Researchers receive $3.4 million NIH grant to assess soccer's tradeoffs with respect to brain health

More than 25 million Americans play soccer, the world's most popular sport. Soccer significantly benefits brain health by boosting aerobic capacity and oxygen and blood flow to the brain, but it also has a downside: Recent studies show that highly repetitive heading of the ball is associated with structural brain changes and worse cognitive performance similar to brain damage caused by concussion.

22 Sep 2022

Researchers secure $4.2 million NIH grant for improving PrEP access and use in the Bronx

Bronx county has the country's fifth-highest rate of HIV diagnosis-;but the lowest rate in New York State for use of HIV pre-exposure prophylaxis (PrEP), medications that are extremely effective in preventing HIV infection.

21 Sep 2022

What are the 2-year health outcomes among patients hospitalized for COVID-19 in China?

A recent study assessed the dynamic trajectory of COVID-19 symptom burden as well as symptom persistence in those who survived SARS-CoV-2 infection for two years after being discharged from hospitals.

20 Sep 2022

Review highlights the role of retinol-binding protein-4 in non-alcoholic fatty liver disease

It is a known fact that consuming a large amount of alcohol, even for a few days, triggers fat accumulation in the liver and ultimately leads to alcohol-related liver diseases.

13 Sep 2022

New cold perfusion approach to isolate hepatic stellate cells from fatty liver-associated tumors

Obesity can give rise to a variety of health concerns. Nonalcoholic steatohepatitis (NASH)-; a type of fatty liver disease that might progress to cancer-; is particularly prevalent among obese people.

12 Sep 2022

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

9 Sep 2022

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Researchers assessed the role of the gut microbiome in human health and disease.

8 Sep 2022

Studies show link between OSA and decline in mental processing powers, increased risk of blood clots, cancer

People who suffer from obstructive sleep apnea (OSA) are at an increased risk of cancer, according to a large study presented on Monday at the European Respiratory Society International Congress in Barcelona, Spain.

5 Sep 2022

Male hypogonadism associated with risk of hospitalization for COVID-19

Men with low testosterone levels are more likely to require hospitalization after COVID-19 infection than men with normal levels or those on testosterone therapy, according to Saint Louis University School of Medicine and Washington University School of Medicine in St. Louis researchers.

2 Sep 2022

The currently available evidence on viral-induced parkinsonism

A new review attempts to summarize all known about the relationship between viral illness and parkinsonian disorders to facilitate further research.

31 Aug 2022

Cedars-Sinai investigators create new blood test for early detection of common liver cancer

Cedars-Sinai Cancer investigators have created a blood test that uses a technology made commonly available during the COVID-19 pandemic to detect the most common form of liver cancer-;at an early enough stage that cure is possible.

30 Aug 2022

New guidelines recommend earlier detection and treatment of pulmonary hypertension

Earlier detection of pulmonary hypertension in the community and expedited referral of high-risk or complex patients are recommended in the European Society of Cardiology (ESC) and European Respiratory Society (ERS) Guidelines for the diagnosis and treatment of pulmonary hypertension, published online today in European Heart Journal and the European Respiratory Journal.

26 Aug 2022

Chinese researchers identify a new molecular mechanism of NASH pathogenesis

Nonalcoholic steatohepatitis (NASH), characterized by liver steatosis, inflammation and injury, has emerged as one of major causes for end-stage liver disease like hepatocellular carcinoma. However, what drives its progression?

25 Aug 2022

The risk of adverse reactions when herbal medications are taken with cancer drugs

A new study discusses phytovigilance initiatives based on the real-world use of herbal drugs in cancer along with conventional chemotherapy.

24 Aug 2022

Researchers discover the vital role of immune cells in liver regeneration

If liver tissue has to be removed due to cancer or another liver disease, the organ usually regenerates quickly, soon becoming fully functional once again.

24 Aug 2022

Direct acting antiviral medications for hepatitis C may improve PTSD symptoms

More than six percent of Americans will develop posttraumatic stress disorder (PTSD) in their lifetime. This potentially chronic condition disrupts lives, and can lead to or exacerbate existing health issues such as depression, anxiety, eating disorders, and suicidal thoughts.

22 Aug 2022

New discovery helps explain the dynamics underlying liver damage in type 2 diabetes and obesity

When fat accumulates in the liver, the immune system may assault the organ. A new study from Weill Cornell Medicine researchers identifies the molecule that trips these defenses, a discovery that helps to explain the dynamics underlying liver damage that can accompany type 2 diabetes and obesity.

19 Aug 2022