Liver Disease News and Research

RSS

The liver is one of the largest solid organs of the body. It is located in the upper right part of the abdomen. Most of the organ lies under cover of the rib cage.

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

26 Jul 2022

Genes underlying cigarette smoking linked to the perception of pain and response to food

Have you ever wondered why one person can smoke cigarettes for a year and easily quit, while another person will become addicted for life? Why can't some people help themselves from abusing alcohol and others can take it or leave it?

20 Jul 2022

New mouse model faithfully mimics brain damage caused by severe Rift Valley Fever virus infection

A new mouse model identified by virologists from the University of Pittsburgh might revolutionize development of therapies targeting brain inflammation caused by Rift Valley Fever virus (RVFV).

15 Jul 2022

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

Researchers have created a liquid biopsy test, which uses two circulating proteins, to test for major liver diseases.

14 Jul 2022

People with non-alcoholic fatty liver disease may have higher risk of dementia

People who have non-alcoholic fatty liver disease, a buildup of fat cells in the liver, may have a higher risk of dementia, according to a new study published in the July 13, 2022, online issue of Neurology®, the medical journal of the American Academy of Neurology.

13 Jul 2022

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

p53 is one of the most important proteins in cancer biology. Often referred to as a "guardian of the genome," p53 becomes activated in response to various cellular stressors like DNA damage.

12 Jul 2022

Researchers discover the first effective drug to treat rare, genetic liver disease

8 Jul 2022

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

A study conducted at the University of São Paulo in Brazil shows that the synthetic molecule Pep19 acts on the endocannabinoid system, which helps regulate and balance key metabolic functions, such as appetite, fat breakdown (lipolysis), and energy release.

5 Jul 2022

New method helps determine alcohol consumption in fatty liver disease

It is important to know whether patients have non-alcoholic fatty liver disease (NAFLD) or alcohol-related liver disease (ALD), as this distinction plays a key role in treatment and prognosis but cannot be reliably determined by established diagnostic means.

5 Jul 2022

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

In a new study, researchers assessed the influence of severe coronavirus disease 2019 on scrotal infections.

5 Jul 2022

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

Spine-related pain is increasingly common in older adults. While medications play an important role in pain management, their use has limitations in geriatric patients due to reduced liver and kidney function, comorbid medical problems and polypharmacy (the simultaneous use of multiple drugs to treat medical conditions).

28 Jun 2022

New tissue model helps trace the steps involved in liver regeneration

The human liver has amazing regeneration capabilities: Even if up to 70 percent of it is removed, the remaining tissue can regrow a full-sized liver within months.

27 Jun 2022

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

In a pair of overlapping studies, a diverse team of researchers, led by scientists at University of California San Diego School of Medicine, have deepened investigations into the genetic origins of nonalcoholic fatty liver disease (NAFLD) in children, describing multiple gene variants (including some previously unknown) that contribute to the risk of developing NAFLD and gene variants associated with the severity of the liver disease.

27 Jun 2022

Study finds higher risk of premature death among patients with pediatric onset immune-mediated inflammatory disease

Patients with a pediatric onset immune-mediated inflammatory disease have a significantly higher risk of premature death, according to new research being presented today at the 54th Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition.

26 Jun 2022

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Need another reason to think twice before ordering that extra helping of fries? It could lead to a higher risk of developing liver cancer.

24 Jun 2022

Simple blood test can predict liver cancer risk in NAFLD patients

An estimated one-quarter of adults in the U.S. have nonalcoholic fatty liver disease (NAFLD), an excess of fat in liver cells that can cause chronic inflammation and liver damage, increasing the risk of liver cancer.

22 Jun 2022

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease.

21 Jun 2022

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Having shown that diet can influence gene expression, science is starting to find out more about how this happens.

15 Jun 2022

Study shows alarming trends in mortality from alcoholic cirrhosis in the U.S.

Alcoholic cirrhosis is an advanced form of alcohol-related liver disease. In the United States between 2010 and 2016, alcohol-related liver disease was the primary cause of nearly 1 in 3 liver transplants, surpassing hepatitis C.

14 Jun 2022

Increasing growth hormone levels can improve liver health in patients with NAFLD

Growth hormone improves liver health in patients with nonalcoholic fatty liver disease (NAFLD) by reducing liver fat and inflammation, according to a new study presented Tuesday, June 14 at ENDO 2022, the Endocrine Society's annual meeting in Atlanta, Ga.

14 Jun 2022

Liver Disease News and Research

Further Reading

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Genes underlying cigarette smoking linked to the perception of pain and response to food

New mouse model faithfully mimics brain damage caused by severe Rift Valley Fever virus infection

New liquid biopsy test found to be highly accurate, sensitive for both NASH and liver fibrosis

People with non-alcoholic fatty liver disease may have higher risk of dementia

Constant activation of p53 in hepatocytes of CLD patients could promote the development of liver cancer

Researchers discover the first effective drug to treat rare, genetic liver disease

Synthetic molecule Pep19 helps regulate and balance key metabolic functions, study shows

New method helps determine alcohol consumption in fatty liver disease

Acute scrotal infections among COVID-19 patients significantly associated with disease severity in new study

Researchers assess the evidence basis for medications used to treat spine-related pain in older adults

New tissue model helps trace the steps involved in liver regeneration

Studies discover multiple gene variants that contribute to the risk and severity of NAFLD in children

Study finds higher risk of premature death among patients with pediatric onset immune-mediated inflammatory disease

Inhibiting pore formation in cells may facilitate prevention, treatment of NASH-associated liver cancer

Simple blood test can predict liver cancer risk in NAFLD patients

Researchers identify the role of TREM2-positive macrophages in non-alcoholic fatty liver disease

Diet supplemented with or deficient in methionine affects gene expression related to liver cell fat metabolism

Study shows alarming trends in mortality from alcoholic cirrhosis in the U.S.

Increasing growth hormone levels can improve liver health in patients with NAFLD

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News