Liver Transplant News and Research

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When a patient presents with end stage liver disease or liver failure he or she may be considered for a liver transplantation. The first step in this is often a rigorous assessment and being placed on a waiting list.

Study: Transplanted livers have a protective effect and reduce potential for organ rejection

Transplanted livers change the profile of blood cells in the recipients, reducing the potential for organ rejection, Mayo Clinic research shows.

18 Apr 2018

Single FMT enema produces sustained and significant improvements in cognitive function

A single treatment using an optimized, targeted form of faecal microbiota transplantation (FMT) produces sustained clinical and cognitive improvements, according to the results of a long-term follow-up of patients with liver cirrhosis and hepatic encephalopathy (HE) who had participated in a short-term study.

16 Apr 2018

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Patients with hepatocellular carcinoma (HCC) waiting for a liver transplant in the USA are now significantly less likely to receive a new liver than they were around a decade ago. A nationwide study presented today at The International Liver Congress™ 2018 in Paris, France, has confirmed that patients with HCC on the liver transplant list in the USA were more than 50% less likely to receive a transplant in 2014-2016 than they were in 2005-2007.

13 Apr 2018

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Kandice Fogle, 43, had just moved to Houston when she began experiencing pain in her back and groin. After undergoing a CT scan, doctors found a large mass in her liver. A biopsy confirmed that she had intrahepatic cholangiocarcinoma, more commonly known as bile duct cancer.

11 Apr 2018

Text messaging may hold promise in helping ALD liver-transplant patients maintain sobriety

Each year in the U.S., more than 40,000 patients need a liver transplant because of complications associated with cirrhosis and liver failure. Alcohol-related liver disease (ALD) alone accounts for nearly 30 percent of all liver transplants, yet up to 50 percent of patients with alcoholism return to drinking within five years of undergoing a liver transplant.

5 Mar 2018

Outcomes have improved for alternatives to whole liver transplants in children, study finds

In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation, such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly.

8 Feb 2018

Moffitt study identifies new drug target that may reduce GVHD risk

Stem cell transplants can cure patients with high-risk leukemia or lymphoma. Graft-versus-host disease is a potentially life-threatening side effect that occurs when the donor's immune cells attack the recipient's normal tissues.

5 Feb 2018

New AASLD guideline focuses on improving diagnosis, treatment of liver cancer and NAFLD

A new Practice Guideline and Practice Guidance in Hepatology will help improve the diagnosis and treatment of patients with liver cancer as well as patients with non-alcoholic fatty liver disease (NAFLD), which can lead to liver cancer and is characterized by the build-up of extra fat in liver cells often due to obesity and diabetes.

27 Jan 2018

Unique liver function of South American amphibian could pave way for finding a cure to cirrhosis

The unique liver function of a South American amphibian, Siphonops annulatus, could pave the way to finding a cure to the devastating liver condition cirrhosis, a new study published in the prestigious Journal of Anatomy reports.

6 Dec 2017

Pioneering research project aims to develop better diagnostic tests for NAFLD

A pioneering European research project aims to lead to new diagnostic tests to assess patients with non-alcoholic fatty liver disease (NAFLD) and identify those most at risk for developing severe inflammation and liver scarring.

21 Nov 2017

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

Poor nutrition is common in patients with liver failure, or cirrhosis, and it can lead to muscle wasting, weakness, fatigue, and worse outcomes before and after patients undergo liver transplantation.

26 Oct 2017

VUMC reaches new milestone after performing 2,000th liver transplant

This month, Vanderbilt University Medical Center performed its 2,000th liver transplant, another milestone for one of the largest liver transplant programs in the Southeast.

20 Oct 2017

Increased use of split liver transplantation could decrease pediatric waitlist deaths

A new study presented this week at The Liver Meeting - held by the American Association for the Study of Liver Diseases - found that increased utilization of split liver transplantation (sharing a donor liver between one pediatric and one adult patient) could decrease the number of children who die awaiting liver transplantation without decreasing liver transplantation access for adult patients.

20 Oct 2017

Study finds rise in pregnancy rates among women with chronic liver disease

A new study presented this week at The Liver Meeting – held by the American Association for the Study of Liver Diseases – found that the overall number of pregnancies in women with chronic liver disease or following liver transplantation has risen over the past 30 years.

20 Oct 2017

Liver Transplant News and Research

Further Reading

Study: Transplanted livers have a protective effect and reduce potential for organ rejection

Single FMT enema produces sustained and significant improvements in cognitive function

Study reports decreasing rates of liver transplantation among HCC patients in the U.S.

Study offers new hope for patients with intrahepatic cholangiocarcinoma

Text messaging may hold promise in helping ALD liver-transplant patients maintain sobriety

Outcomes have improved for alternatives to whole liver transplants in children, study finds

Moffitt study identifies new drug target that may reduce GVHD risk

New AASLD guideline focuses on improving diagnosis, treatment of liver cancer and NAFLD

Unique liver function of South American amphibian could pave way for finding a cure to cirrhosis

Pioneering research project aims to develop better diagnostic tests for NAFLD

New review addresses aspects of nutrition in liver transplant candidates with cirrhosis

VUMC reaches new milestone after performing 2,000th liver transplant

Increased use of split liver transplantation could decrease pediatric waitlist deaths

Study finds rise in pregnancy rates among women with chronic liver disease

Alcohol use may induce changes to cholesterol-regulating gene

UCLA awarded $8.4 million NIH grant to improve outcomes for liver transplant recipients

Loyola Medicine reaches another major milestone with successful first pancreas transplant

Vision research using donated human tissue could help millions suffering from diabetic eye disease

Blood cleaning device can also effectively provide a bridge to liver transplantation

Routinely used hospital tool can predict poor outcomes in liver transplant recipients

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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