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New gene therapy approach could help prevent blindness in children with Leber congenital amaurosis

Researchers from the National Eye Institute have developed a gene therapy that rescues cilia defects in retinal cells affected by a type of Leber congenital amaurosis (LCA), a disease that causes blindness in early childhood.

8 Sep 2022

Trial compares two different lung volume reduction procedures for people with emphysema

The first randomized controlled trial to compare two different lung volume reduction procedures for people with emphysema has found that both lead to similar improvements in lung function, breathlessness and exercise capacity.

5 Sep 2022

Bronchodilators do little to help people without COPD but have smoking-related respiratory symptoms

Researchers supported by the National Institutes of Health have found that dual bronchodilators - long-lasting inhalers that relax the airways and make it easier to breathe - do little to help people who do not have chronic obstructive pulmonary disease (COPD), but who do have respiratory symptoms and a history of smoking.

5 Sep 2022

Male hypogonadism associated with risk of hospitalization for COVID-19

Men with low testosterone levels are more likely to require hospitalization after COVID-19 infection than men with normal levels or those on testosterone therapy, according to Saint Louis University School of Medicine and Washington University School of Medicine in St. Louis researchers.

2 Sep 2022

Men with low testosterone may have higher risk of COVID-19 hospitalization

Men with low testosterone who develop COVID-19 are at elevated risk of becoming seriously ill and ending up in the hospital, according to a study by researchers at Washington University School of Medicine in St. Louis and Saint Louis University School of Medicine.

2 Sep 2022

Combination of anemia and weak muscles increases the risk of death in older people

A study by researchers at the Federal University of São Carlos in Brazil and University College London in the United Kingdom shows that a combination of anemia and weak muscles in older people heightens the risk of death in ten years by 64% for men and by 117% for women.

29 Aug 2022

Study: Survival following sudden cardiac arrest has more than doubled in 30 years

The probability of surviving sudden cardiac arrest outside hospital has more than doubled in 30 years. This is shown by a national Swedish register study covering more than 130,000 cases.

26 Aug 2022

New guidelines recommend earlier detection and treatment of pulmonary hypertension

Earlier detection of pulmonary hypertension in the community and expedited referral of high-risk or complex patients are recommended in the European Society of Cardiology (ESC) and European Respiratory Society (ERS) Guidelines for the diagnosis and treatment of pulmonary hypertension, published online today in European Heart Journal and the European Respiratory Journal.

26 Aug 2022

Smoking and the risk of contracting SARS-CoV-2 and COVID-19

A recent study examines the potential effects of tobacco use on COVID-19.

21 Aug 2022

Nepal has the highest death rate from chronic obstructive pulmonary disease, study reveals

Nepal has the world's highest age-adjusted death rate for chronic lung disease at 182.5 per 100,000 population, with more than 3,000 years lost to ill health or disability from the condition, according to an international study.

18 Aug 2022

Genetic variant associated with Alzheimer's disease plays a role in protecting against glaucoma

New research led by scientists at Mass Eye and Ear and Brigham and Women's Hospital, member hospitals of Mass General Brigham, reveals the role that a genetic variant associated with Alzheimer's disease, APOE4, plays in protecting against glaucoma.

16 Aug 2022

Vaccines and monoclonal antibodies being developed for respiratory syncytial virus

A new study reviews recent advancements made in the development of RSV immunoprophylactic measures.

11 Aug 2022

CDC identifies bacteria that cause rare melioidosis in domestic environmental samples

The Centers for Disease Control and Prevention (CDC) has identified for the first time in domestic environmental samples the bacteria that causes a rare and serious disease called melioidosis.

8 Aug 2022

Smaller lung airways in women can lead to a higher risk for COPD

Structural differences in lung airways between men and woman may be the cause of differences in chronic obstructive pulmonary disease (COPD) prevalence and outcomes between the sexes.

2 Aug 2022

New AI algorithm accurately and quickly diagnoses idiopathic pulmonary fibrosis

A Nagoya University research group has developed an AI algorithm that accurately and quickly diagnoses idiopathic pulmonary fibrosis, a lung disease. The algorithm makes its diagnosis based only on information from non-invasive examinations, including lung images and medical information collected during daily medical care.

28 Jul 2022

Study finds disparities in first evaluation of infants with cystic fibrosis from minoritized groups

Infants from minoritized racial and ethnic backgrounds who have positive newborn screening tests for cystic fibrosis received their diagnostic follow-up for the disease later than recommended and later than white, non-Hispanic infants, according to a study published in the Journal of Cystic Fibrosis.

27 Jul 2022

Attending daycare may increase lung complications in preterm children with bronchopulmonary dysplasia

Attending daycare in the first three years of life is linked with an increase in lung complications in children who were born prematurely and diagnosed with a form of chronic lung disease, according to new research led by Children's Hospital of Philadelphia.

26 Jul 2022

SLU and industry partners report the first effective drug to treat rare, genetic liver disease

Researchers at Saint Louis University's School of Medicine, in collaboration with Arrowhead Pharmaceuticals and Takeda Pharmaceuticals, report the first effective drug to treat a rare, genetic liver disease that formerly could only be treated with a liver transplant.

26 Jul 2022

Anti-SARS-CoV-2 nucleocapsid antibodies and pre-existing lung diseases may be independent predictors of long COVID

Researchers evaluated the incidence of long coronavirus disease (long COVID) in a demographically diverse population with different disease severities to inform clinicians and future vaccine development strategies.

21 Jul 2022

Study offers insight into the basic cellular pathologies driving interstitial lung disease

While most people recover from COVID-19 within a week or two, up to one-third of survivors experience persistent or new symptoms weeks and months after initial infection.