Lupus Erythematosus News and Research

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First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CAR T-cell therapy.

19 Apr 2023

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

Researchers reviewed data on the incidence of autoimmune diseases in the post-acute coronavirus disease 2019 period.

17 Apr 2023

How do viral infections cause autoimmune diseases?

Researchers describe the pathological mechanisms of virus-induced autoimmune diseases.

28 Mar 2023

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

15 Mar 2023

Vaccination protects lupus patients from contracting COVID-19

Researchers determine the risk of COVID-19 and possibility of severe sequelae in patients with systemic lupus erythematosus and the general population.

14 Mar 2023

New guideline focuses on the timing of hip and knee arthroplasty

The American College of Rheumatology and the American Association of Hip and Knee Surgeons released a summary of its new guideline titled "the Optimal Timing of Elective Hip or Knee Arthroplasty for Patients with Symptomatic Moderate to Severe Osteoarthritis or Osteonecrosis Who Have Failed Nonoperative Therapy."

14 Mar 2023

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

Researchers investigated whether mRNA technology-based COVID-19 vaccines promote the development of autoantibodies.

14 Mar 2023

C-reactive protein has a beneficial function in systemic lupus erythematosus

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Researchers performed multi-organ single-cell RNA sequencing of collagen-induced arthritis murine model to evaluate immune-mediated inflammatory disease alterations by characterizing the genome, organizing the organome, and prioritizing pathways in the multi-organ data.

3 Mar 2023

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

In a recent study published in the journal Fermentation, researchers reviewed studies examining the role of butyrate in inflammatory responses, immunological properties, and diseases related to the immune system such as atopic dermatitis, systemic lupus erythematosus, human immunodeficiency virus (HIV), psoriasis, and cancer.

24 Feb 2023

Study highlights the interconnectedness of autoimmunity and cancer

In a recent study published in the journal Immunity, researchers reviewed the T cell response in cancer and autoimmunity to propose strategies for more effective immunotherapies.

15 Feb 2023

The safety profile and the actual known adverse effects of COVID-19 vaccines in at-risk and healthy individuals

Researchers discussed the safety of COVID-19 vaccines in healthy people and patients with autoimmunity or cardiac issues.

7 Feb 2023

Spontaneous coronary artery dissection: The leading cause of pregnancy-associated heart attacks

Despite increased awareness over the past decades, only about half (56%) of women recognize that heart disease is their No. 1 killer. Heart disease is the leading cause of death for women in the United States, accounting for 1 in every 5 female deaths.

3 Feb 2023

Researchers discover the impact of microRNA on inflammation in lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice.

26 Jan 2023

Researchers review the association between endogenous retrovirus reactivation and aging

Researchers explored the role of endogenous retrovirus (ERV) reactivation in the aging process.

24 Jan 2023

Targeting T cell iron metabolism may offer a new approach for treating lupus

Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) -; the most common form of the chronic autoimmune disease lupus.

13 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

COVID-19 outcomes in Rituximab treated patients

A new report throws light on SARS-CoV-2 breakthrough infections in patients with certain joint diseases or musculoskeletal conditions who are on rituximab and compares the severity of COVID-19 outcomes in these patients whilst identifying potential risk factors for severe outcomes.

11 Jan 2023

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

The Lupus Research Alliance (LRA) proudly announces the two outstanding recipients of the 2022 Distinguished Innovator Award (DIA): Hongbo Chi, PhD, and Joseph Craft, MD.

16 Dec 2022

CAR T therapy extends its reach beyond oncology

Engineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can do to fight blood cancers.

23 Nov 2022

Lupus Erythematosus News and Research

First-in-human clinical study begins investigating the duoCAR T-cell therapy for treatment of HIV

Is there an association between COVID-19 and the risk of developing an autoimmune disease?

How do viral infections cause autoimmune diseases?

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Vaccination protects lupus patients from contracting COVID-19

New guideline focuses on the timing of hip and knee arthroplasty

Study suggests mRNA vaccines decouple SARS-CoV-2 immunity from autoantibody responses observed during acute COVID-19

C-reactive protein has a beneficial function in systemic lupus erythematosus

Multi-organ scRNA-seq reveals targeting pro- or anti-inflammatory regulators may be exploited for personalized treatment of immune diseases

Exploring the immunomodulatory and anti-inflammatory properties of butyrate

Study highlights the interconnectedness of autoimmunity and cancer

The safety profile and the actual known adverse effects of COVID-19 vaccines in at-risk and healthy individuals

Spontaneous coronary artery dissection: The leading cause of pregnancy-associated heart attacks

Researchers discover the impact of microRNA on inflammation in lupus

Researchers review the association between endogenous retrovirus reactivation and aging

Targeting T cell iron metabolism may offer a new approach for treating lupus

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

COVID-19 outcomes in Rituximab treated patients

Lupus Research Alliance announces recipients of the 2022 Distinguished Innovator Award focused on studying T cells in lupus

CAR T therapy extends its reach beyond oncology

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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