Lymph Nodes News and Research

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Angiogenesis gene polymorphisms predict tumor recurrence in stage II and III colon cancer

Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.

8 Jun 2007

Blocking the action of beta1-integrin to treat cancer

Targeting the function of a protein known as beta1-integrin might represent a novel approach to cancer treatment, according to a paper published online in the EMBO Journal.

8 Jun 2007

Diet may influence survival after treatment for stage III colon cancer

Patients with stage III colon cancer who have undergone surgery and chemotherapy with the goal of cure may have a higher risk of relapsing and dying early if they follow a predominantly Western diet of red meat, fatty foods, refined grains, and desserts, according to research led by investigators at Dana-Farber Cancer Institute in Boston.

5 Jun 2007

Benefits of Herceptin are lasting

An updated analysis of two large randomized clinical trials has found that breast cancer patients who received the monoclonal antibody trastuzumab (Herceptin) along with chemotherapy are living longer and with less risk of recurrent disease, compared to patients treated with chemotherapy alone.

5 Jun 2007

Natalizumab returns to market

Just months after receiving FDA approval, natalizumab, a medication for the treatment of multiple sclerosis (MS) and other inflammatory disorders, was voluntarily withdrawn by its manufacturers after three patients developed a brain infection known as Progressive Multifocal Leukoencephalopathy (PML).

28 May 2007

Heart-assist device gives Culver City man a better quality of life

Mark Heiner of Culver City reads books, paints artistically, takes walks and does laundry – activities that would be considered routine except for the fact that a four-pound disk implanted in his abdominal cavity is keeping his blood flowing.

28 May 2007

Scientists develop method to track immune system enzyme in live animals

Scientists supported by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) at the National Institutes of Health have created two mouse strains that will permit researchers to trace, in a live animal, the activity of an enzyme believed to play a crucial role both in the normal immune response as well as autoimmunity and B cell tumor development.

18 May 2007

PET-CT is better for early detection of muscular lymphoma than CT alone

For the study, PET-CT was used to image 305 patients with lymphoma. Twelve of these patients had muscular involvement in which 10 were biopsy proven and two were proven by imaging follow-up.

8 May 2007

How inhaled anthrax paralyzes the body's defenses

University of Florida researchers have revealed how the inhaled form of anthrax paralyzes the body's defenses and prevents immune cells from reaching the site of infection.

8 May 2007

Hepatitis C increases risk for non-Hodgkin's lymphoma

Researchers in the U.S. have found that an infection with the hepatitis C virus increases the risk of a person developing non-Hodgkin's lymphoma.

8 May 2007

Johns Hopkins team stops form of blood cancer in its tracks

A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres.

26 Apr 2007

Schering-Plough plans phase III trials for novel selective antiplatelet therapy

Schering-Plough Corporation has announced plans to initiate two global Phase III large-scale clinical outcomes trials for its novel selective oral antiplatelet therapy, the thrombin receptor antagonist (TRA) SCH 530348.

20 Apr 2007

Hospital-based performance measures for quality of care for breast and colorectal cancer

In a move more than two years in the making, a National Quality Forum (NQF) endorsement became effective today of the first nationally recognized hospital-based performance measures for quality of care for breast and colorectal cancer.

15 Apr 2007

New imaging technology with use of novel contrast agent may predict heart attack in waiting

A new imaging technology may hold the key to not only stopping heart attacks in their tracks but also preventing them for ever occurring.

10 Apr 2007

Blood pressure drug shows potential as lung cancer treatment

A hormone that is important in the control of blood pressure also shrinks lung cancer tumors in mice, suggesting a new way to prevent or treat the deadly cancer, according to scientists at Wake Forest University School of Medicine.

19 Mar 2007

Study aims to find which breast cancer patients need chemotherapy

Most postmenopausal women with small breast tumors don't need chemotherapy to reduce their recurrence risk after lumpectomy.

13 Mar 2007

Quantum dots detect metastatic lesions

By injecting quantum dots into tumors, investigators at Carnegie Mellon University have been able to image sentinel lymph nodes in animals using near-infrared light. These results could lead to a simple, non-invasive method for detecting metastasis.

26 Feb 2007

New test shows which breast cancers will recur

Approval has been granted by the FDA for a gene-based test that helps tell early-stage breast cancer patients whether they need chemotherapy after their surgery.

7 Feb 2007

FDA clears MammaPrint test for marketing

The Food and Drug Administration (FDA) has cleared for marketing a test that determines the likelihood of breast cancer returning within five to 10 years after a woman's initial cancer. It is the first cleared molecular test that profiles genetic activity.

6 Feb 2007

Study shows why the body's immune system doesn't attack tissues in the small intestine

Answering one of the oldest questions in human physiology, researchers at Dana-Farber Cancer Institute have discovered why the body's immune system - perpetually on guard against foreign microbes like bacteria - doesn't attack tissues in the small intestine that harbor millions of bacteria cells.

9 Jan 2007