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Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

Research discusses the process of discovering anti-inflammatory and neuroprotective drugs from medicinal plants found in the Australian rainforest. It focuses on the pathways from the discovery of bioactive plants to the validation in an appropriate neuro-inflammatory mouse model, using some examples from their current research.

9 Jul 2023

How does space affect the immune system of astronauts?

Research explores the effects of microgravity and radiation on the immune system in space conditions. It emphasizes the need to understand these effects for future long-duration space missions and highlights knowledge gaps for further investigation.

2 Jul 2023

Long-term protection unveiled: hybrid immunity guards against Omicron reinfections

Researchers evaluated the impact of SARS-CoV-2 Wuhan-Hu-1 strain (WH1) immune imprinting on antibody-based immunological responses.

26 Jun 2023

Battle against RSV: Computational design paves way for new polyvalent vaccine

Research focuses on the design of a multi-epitope polyvalent vaccine against Human Respiratory Syncytial Virus (RSV), a leading cause of lower respiratory tract infections. The study utilizes computational methods and immunoinformatics tools to predict potential vaccine candidates and their interactions with Toll-like receptors (TLRs).

19 Jun 2023

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Researchers reported on the contribution of trained immune responses to protection against SARS-CoV-2 infections and future pandemics.

16 Jun 2023

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Researchers evaluated the therapeutic efficacy of Navoximod.

13 Jun 2023

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

In a recent article published in the journal JAMA Network, researchers performed a randomized clinical trial (RCT) to demonstrate the noninferiority of letermovir vs. valganciclovir for prophylaxis of cytomegalovirus (CMV) in adult CMV-seronegative kidney transplant recipients (KTRs) who received a kidney from a CMV-seropositive individual.

13 Jun 2023

Helicobacter pylori infection found to lower cognition among adults in the UK

Researchers evaluated the association between Helicobacter pylori and cognition.

9 Jun 2023

Two studies spotlight intestinal T cells that could be targeted to prevent resistance to ICB cancer therapy

Two new studies in Science and Science Immunology spotlight a group of intestinal T cells with α4β7 integrin receptors that could be targeted to prevent resistance to immune checkpoint blockade (ICB) cancer immunotherapy.

8 Jun 2023

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Researchers describe the Treg-cell-inducing activity of lipid extracts from the feces of specific-pathogen-free mice.

6 Jun 2023

Key insights into immune responses after COVID-19 vaccination in Indigenous people

Researchers evaluated immune responses to COVID-19 BNT162b2 mRNA vaccinations among Indigenous Australian First Nations (FN) individuals by comorbidity and ethnicity.

1 Jun 2023

Computational approach could help pinpoint causal variants in the noncoding genome

Less than two percent of the human genome codes for proteins, with the rest being noncoding and likely helping with gene regulation.

30 May 2023

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Researchers develop a lipid nanoparticle-formulated mRNA-based antigen encoding three SARS-CoV-2 peptides derived from non-structural proteins.

25 May 2023

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 9, entitled, "Highly multiplexed immune profiling throughout adulthood reveals kinetics of lymphocyte infiltration in the aging mouse prostate."

24 May 2023

Long-COVID's crippling aftermath: Study reveals persistent symptoms severely impact quality of life, especially in women

Research examines the impact of long-Covid syndrome on the health-related quality of life (HRQoL) of patients with mild or moderate SARS-CoV-2 infections. It reveals significant impairments in physical and mental health, emphasizing the need for long-term surveillance and support for affected individuals.

16 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

Malnutrition looms over Japan's 'Cinderella weight' women: Study warns of health risks

Study aimed to determine the nutritional status of young women at "Cinderella weight" in Japan. The results showed that underweight women had lower handgrip strength, cholesterol levels, and lymphocyte count and were prone to malnutrition due to low dietary diversity and deficiencies in various vitamins and minerals.

9 May 2023

Lymphocyte News and Research

Australian rainforest remedies: Scientists explore bioactive plant compounds as potential anti-neuroinflammatory agents

How does space affect the immune system of astronauts?

Long-term protection unveiled: hybrid immunity guards against Omicron reinfections

Battle against RSV: Computational design paves way for new polyvalent vaccine

Trained immunity: its role in COVID-19 and potential in preparing for future infectious outbreaks

Breaking barriers: hydrogel reservoir unleashes the potential of HSV-1 virotherapy in cancer

Letermovir: A promising breakthrough in CMV prevention for kidney transplant recipients

Helicobacter pylori infection found to lower cognition among adults in the UK

Two studies spotlight intestinal T cells that could be targeted to prevent resistance to ICB cancer therapy

How lipid metabolites in the gut aid in regulatory T-cell differentiation

Key insights into immune responses after COVID-19 vaccination in Indigenous people

Computational approach could help pinpoint causal variants in the noncoding genome

T-cell-inducing mRNA COVID-19 vaccine improves effectiveness

Study characterizes how the inflammatory microenvironment of adult mouse prostate changes during aging

Long-COVID's crippling aftermath: Study reveals persistent symptoms severely impact quality of life, especially in women

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Malnutrition looms over Japan's 'Cinderella weight' women: Study warns of health risks

Upregulated expression of many LY6 genes linked to poor survival in endometrial cancer patients

Neutrophils found to play a key role in fibromyalgia pain

What are the gastrointestinal benefits of consuming soybean?

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