Lymphoma News and Research

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Lymphoma is cancer that begins in cells of the immune system. There are two basic categories of lymphomas. One kind is Hodgkin lymphoma, which is marked by the presence of a type of cell called the Reed-Sternberg cell. The other category is non-Hodgkin lymphomas, which includes a large, diverse group of cancers of immune system cells. Non-Hodgkin lymphomas can be further divided into cancers that have an indolent (slow-growing) course and those that have an aggressive (fast-growing) course. These subtypes behave and respond to treatment differently. Both Hodgkin and non-Hodgkin lymphomas can occur in children and adults, and prognosis and treatment depend on the stage and the type of cancer.

Montana looks to become latest state to boost nonprofit hospital oversight

Montana's proposal to increase oversight is part of a national trend by states to ensure nonprofit hospitals act as charitable organizations as they claim tax-exempt status.

25 Jul 2024

Study highlights infection as major post-CAR-T therapy challenge

In patients with diffuse large B-cell non-Hodgkin lymphoma (DLBCL), the two hallmark post-chimeric antigen receptor (CAR)-T therapy toxicities are extremely rare after two weeks, supporting a shorter, more flexible toxicity monitoring period, according to a study published in Blood Advances.

25 Jul 2024

Pesticide use in agriculture may pose cancer risks similar to smoking

In modern day agriculture, pesticides are essential to ensure high enough crop yields and food security.

25 Jul 2024

Researchers discover new target for treating diseases linked to T-cell leukemia virus type 1

A team of researchers from Penn State College of Medicine found a new target for treating diseases associated with human T-cell leukemia virus type 1 (HTLV-1).

22 Jul 2024

USC scientists transform B cells into cancer and HIV destroyers

USC scientists have discovered a way to turn the body's B cells into tiny surveillance machines and antibody factories that can pump out specially designed antibodies to destroy cancer cells or HIV, two of medicine's most formidable foes.

22 Jul 2024

Research shows the ability of proteins to predict onset of many diverse diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

22 Jul 2024

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

The effectiveness of CAR T cell therapy against a variety of cancers, including solid tumors, could be boosted greatly by using CRISPR-Cas9 technology to knock out the gene for CD5, a protein found on the surface of T cells, according to a preclinical study from investigators at the University of Pennsylvania's Perelman School of Medicine and Abramson Cancer Center.

19 Jul 2024

Tufts researchers uncover immune cell link to doxorubicin-induced heart damage

There's still much to learn about how doxorubicin, a 50-year-old chemotherapy drug, causes its most concerning side effects.

17 Jul 2024

NYU Langone Health earns No. 1 spot in neurology and neurosurgery for the third straight year

NYU Langone Health has reaffirmed its position as the nation's top hospital for neurology and neurosurgery, securing the No. 1 ranking for the third straight year in U.S. News & World Report's annual assessment of leading hospitals.

16 Jul 2024

40% of US cancer cases linked to lifestyle choices

Nearly 40% of cancer cases and 44% of cancer deaths in 2019 were due to modifiable risk factors, with cigarette smoking as the leading cause. This study highlights the potential to significantly reduce cancer burden through lifestyle changes.

14 Jul 2024

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

CAR-T cell therapy, which targets a specific protein on the surface of cancer cells, causes tumors to shrink or disappear in about half of patients with large B-cell lymphoma who haven't experienced improvement with chemotherapy treatments.

11 Jul 2024

Novel Co-STAR cells show promise in targeting and eradicating cancer

Using genetic engineering techniques, investigators at the Johns Hopkins Kimmel Cancer Center and its Ludwig Center, the Lustgarten Laboratory and Bloomberg~Kimmel Institute for Cancer Immunotherapy have designed a novel type of cell to recognize and fight cancer.

11 Jul 2024

Scientists discover a molecular defect that promotes pathologic immune response in lupus

Northwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic immune response in systemic lupus erythematosus (known as lupus) and show that reversing this defect may potentially reverse the disease.

10 Jul 2024

Hesse's LOEWE program supports cutting-edge CAR-T cell therapy research

LOEWE, the federal state of Hesse's research promotion program for the development of scientific and economic excellence, is providing €4.8 million in funding for a new research network spearheaded by Goethe University.

28 Jun 2024

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Researchers investigated whether stem-like T lymphocytes are involved in ulcerative colitis pathogenesis.

21 Jun 2024

Combining JAK inhibitors with checkpoint inhibitors improves cancer immunotherapy response

Because not all cancer patients respond to a leading type of cancer immunotherapy drug, known as an immune checkpoint inhibitor, scientists explored whether adding janus kinase (JAK) inhibitors – drugs that treat chronic inflammation – could help.

20 Jun 2024

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Checkpoint inhibitor therapies can be thought of as the molecular "brake release" for the immune system.

20 Jun 2024

Non-chemotherapy treatment regimen achieves full remission in aggressive B-cell lymphoma

Researchers at the National Institutes of Health (NIH) have developed a non-chemotherapy treatment regimen that is achieving full remissions for some people with aggressive B-cell lymphoma that has come back or is no longer responding to standard treatments.

19 Jun 2024

Rapid test detects brain cancer mutations in cerebrospinal fluid

A test that looks for genetic hallmarks of brain cancers in samples of cerebrospinal fluid can decrease the time to diagnosis and eliminate the need for invasive brain biopsies for some patients.

17 Jun 2024

Case study sheds light on CAR-T therapy-related secondary cancers

A new detailed analysis of a patient's second cancer after receiving CAR-T therapy for the initial cancer provides rare but important insights intended to offer helpful guidance for oncologists and pathologists about the clinical presentation and pathologic features involved in a CAR-T related second cancer.

13 Jun 2024

Lymphoma News and Research

Further Reading

Montana looks to become latest state to boost nonprofit hospital oversight

Study highlights infection as major post-CAR-T therapy challenge

Pesticide use in agriculture may pose cancer risks similar to smoking

Researchers discover new target for treating diseases linked to T-cell leukemia virus type 1

USC scientists transform B cells into cancer and HIV destroyers

Research shows the ability of proteins to predict onset of many diverse diseases

CD5 knockout using CRISPR boosts CAR T cell therapy efficacy

Tufts researchers uncover immune cell link to doxorubicin-induced heart damage

NYU Langone Health earns No. 1 spot in neurology and neurosurgery for the third straight year

40% of US cancer cases linked to lifestyle choices

CD22-targeted CAR-T therapy shows promising results in relapsed large B-cell lymphoma

Novel Co-STAR cells show promise in targeting and eradicating cancer

Scientists discover a molecular defect that promotes pathologic immune response in lupus

Hesse's LOEWE program supports cutting-edge CAR-T cell therapy research

Research finds stem-like T cells are associated with pathogenesis in ulcerative colitis

Combining JAK inhibitors with checkpoint inhibitors improves cancer immunotherapy response

JAK inhibitor ruxolitinib enhances immunotherapy in Hodgkin lymphoma patients

Non-chemotherapy treatment regimen achieves full remission in aggressive B-cell lymphoma

Rapid test detects brain cancer mutations in cerebrospinal fluid

Case study sheds light on CAR-T therapy-related secondary cancers

E-Cigarettes and Ethanol: A forensic Perspective on Vaping

Understanding Consumer-Consented Data to Optimize Digital Health Programs

The Future is Wearable: Advancing Human Health Through Portable Spectroscopy

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