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Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers developed covalent nanobodies to neutralize severe acute respiratory syndrome coronavirus-2 and its variants.

18 Mar 2022

Researchers discover a novel group of proteins that exists in all domains of life

Proteins are the "workhorses" in every living cell and constitute the chemical basis of life. These little machines are required to turn food into energy, to manage motion and brain activities and to fight off bacteria and viruses.

17 Feb 2022

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors (β-ARs).

14 Feb 2022

New study to help understand the effect of cancer medicine

When the muscles become acidic after doing too many press-ups, squats or cycling to work, it is because of lactic acid.

21 Jan 2022

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

A new study suggests that coronaviruses such as SARS-CoV-2 depend on a furin cleavage site between the S1/S2 subunits to enhance viral infectivity.

20 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

SARS-CoV-2 Delta binds more strongly to furin protease than other existing variants

Researchers conducted a computational analysis of the furin cleavage domain (FCD) of SARS-CoV-2 and its variants, as well as several other viruses.

10 Jan 2022

Exploring SARS-CoV-2-like viruses to mitigate the risk of zoonotic transmission to humans

In a new study, a team of researchers developed a genetic assay to evaluate several clade 2 and clade 3 receptor-binding domains (RBD) of spike (S) protein sequences of genus sarbecovirus.

5 Jan 2022

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Now in new research, scientists from the University of Leicester have been investigating how these mutations alter the affinities of RBDs to ACE2.

28 Dec 2021

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

A molecular building block of many animal proteins, the amino acid valine, plays a key role in cancerous growth seen in T cell acute lymphoblastic leukemia, a new study shows.

22 Dec 2021

Computational comparison of SARS-CoV-2 Delta and Omicron variant binding affinity with ACE2

Researchers from the Management and Science University in Malaysia have used computational tools to investigate the new variant.

8 Dec 2021

The emergence and evolution of SARS-CoV-2 and its VOCs

A review article discusses the evolution of SARS-CoV-2 and the emergence of variants of concern.

5 Dec 2021

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Scientists generate a VLP type NP platform made of recombinant viral antigens conjugated with TMV virions.

23 Nov 2021

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Cryogenic electron microscopy (cryo-EM) has enabled researchers to study how the DNA replication machinery assembles at sites where DNA is damaged.

22 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Mothers pass on the legacy of stress exposure to future generations

A mother's response to stress can even influence her grandchildren. Biologists at the University of Iowa found that roundworm mothers subjected to heat stress passed, under certain conditions and through modifications to their genes, the legacy of that stress exposure not only to their offspring but even to their offspring's children.

13 Oct 2021

Lysine News and Research

Covalent protein nanobodies for neutralizing SARS-CoV-2 and its variants

Researchers discover a novel group of proteins that exists in all domains of life

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

New study to help understand the effect of cancer medicine

Researchers explore furin inhibitors as a potential tool for treating COVID-19 infection

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

SARS-CoV-2 Delta binds more strongly to furin protease than other existing variants

Exploring SARS-CoV-2-like viruses to mitigate the risk of zoonotic transmission to humans

Researchers investigate the effect of emerging SARS-CoV-2 mutations on ACE2 binding

Amino acid valine plays a key role in the growth of T cell acute lymphoblastic leukemia

Computational comparison of SARS-CoV-2 Delta and Omicron variant binding affinity with ACE2

The emergence and evolution of SARS-CoV-2 and its VOCs

Tobacco mosaic virus nanoparticle-based novel COVID-19 vaccine candidate

Cryo-EM reveals how the DNA replication machinery assembles at DNA damage sites

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

Mothers pass on the legacy of stress exposure to future generations

Super-resolution imaging and size analysis of SARS-CoV-2 virus particles

Hyperbranched polylysine nanopolymer as potential broad-spectrum antiviral against SARS-CoV-2

Researchers identify key factor responsible for brain development during evolution

Researchers find potential new target for treating systemic inflammation in obesity

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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