Major Depressive Disorder News and Research

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Major Depressive Disorder (MDD) is a psychiatric condition characterized by depressed mood or anhedonia (significant loss of interest or pleasure). The condition affects more than 15.7 million adults and approximately 3 million adolescents (aged 13 to 17 years) in the USA each year.

'Mindfulness' lifts depression for many, but not all

Mindfulness, a central concept in yoga and various forms of meditation, has proven to be effective against depression, but difficult to grasp for a significant number of people who try it, according to a University of Calgary researcher.

23 Jan 2006

People with mild symptoms of depression pay more attention to their social environment

Surprisingly, people with mild depression are actually more tuned into the feelings of others than those who aren't depressed, a team of Queen's psychologists has discovered.

28 Nov 2005

New gene linked to schizophrenia and depression

A Scots-led medical research team has identified a new gene linked to major mental illness that links back to a previously discovered gene known to increase the risk of schizophrenia and depression.

20 Nov 2005

Bright light therapy may aid patients with depressive and bipolar disorders

A report in the November Cell Metabolism reveals powerful effects of light on the adrenal glands, a finding that might explain the broad benefits of bright light therapy for a variety of conditions, including sleep and depressive disorders, according to researchers.

14 Nov 2005

New York-Presbyterian Hospital offers Vagus Nerve Stimulation (VNS) Therapy

New York-Presbyterian Hospital/Columbia University Medical Center is the first in the greater New York City-area to offer Vagus Nerve Stimulation (VNS) Therapy as a long-term treatment specifically approved by the FDA for treatment-resistant depression (TRD).

7 Nov 2005

Strong relationship of major depressive disorder to alcohol use disorders, drug disorders and other mental health conditions

Findings from the largest survey ever conducted on the co-occurrence of psychiatric disorders among U.S. adults indicates a sharper picture than previously reported of major depressive disorder (MDD) in specific population groups.

27 Oct 2005

Protein Oct-6 is not a biological marker for schizophrenia

The protein Oct-6 is not a biological marker for schizophrenia. The results of a study published today in the open access journal BMC Psychiatry contradict previous findings and show that Oct-6, a protein involved in neurodevelopment, is normally expressed in the adult brain and cannot be used to identify patients with schizophrenia.

23 Oct 2005

Sharper picture than previously available of major depressive disorder

Findings from the largest survey ever mounted on the co-occurrence of psychiatric disorders among U.S. adults afford a sharper picture than previously available of major depressive disorder (MDD) in specific population subgroups and of MDD's relationship to alcohol use disorders (AUDs) and other mental health conditions.

3 Oct 2005

Effects of 10 commonly prescribed second-generation antidepressants studied

Because clinical depression is so disabling and affects more than 16 percent of adults in the United States at some time in their lives, researchers have worked hard to develop more effective treatments. But how much better are the newer pharmaceuticals?

21 Sep 2005

Depression improved during telephone therapy in multiple sclerosis patients

Patients with multiple sclerosis showed significant improvement in their depression during 16 weeks of telephone-administered psychotherapy treatment, according to an article in the September issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

5 Sep 2005

Vagus nerve stimulation (VNS) therapy for treatment-resistant depression proves effective for some patients

Vagus nerve stimulation (VNS) therapy, a treatment recently approved by the Food and Drug Administration for treatment-resistant depression, produced a positive response in more than 25 percent of patients in a national, yearlong study led by UT Southwestern Medical Center psychiatrists

31 Aug 2005

Some medical conditions increase risk for developing major depression while others do not

Those who feel sad and lack an interest in regular life activities for at least two weeks and qualify for a diagnosis of minor depression are six times as likely to develop major depression compared to those who don't have these symptoms, according to a longitudinal study on risks for depression.

22 Aug 2005

Cognitive therapy can have a preventive effect for depression

Three years ago, Terry Tuton was laid off from his job as project manager at a large technology firm, leaving him limited insurance coverage at a time when he was suffering from overpowering feelings of hopelessness and depression - and not for the first time in his life.

4 Aug 2005

FDA approval for VNS Therapy will help people with epilepsy

The U.S. Food and Drug Administration's recent approval of Vagus Nerve Stimulation Therapy for treatment of chronic depression provides a novel single-treatment option for two major symptoms suffered by people with epilepsy.

21 Jul 2005

Five basic steps to help doctors identify and treat insomnia in elderly patients

Researchers outline five basic steps to help doctors identify and treat insomnia in elderly patients. This article is published in a special insomnia themed supplement of the Journal of the American Geriatrics Society.

14 Jul 2005

GlaxoSmithKline announces availability of Paxil CR to U.S. market

GlaxoSmithKline announced today the availability of Paxil CR (paroxetine hydrochloride controlled release) tablets in pharmacies across the United States. Other markets will follow shortly thereafter.

27 Jun 2005

Bipolar disorder more prevalent and costly than believed

The incidence of bipolar disorder in the general population is considerably higher than earlier studies have indicated, resulting in significantly less productivity and more days lost from work compared to the better known major depressive disorder, according to preliminary findings from a national survey presented today at the Sixth International Conference on Bipolar Disorder.

19 Jun 2005

Newly developed treatment for severe grief shown more effective than standard therapy

A recently developed method for treating complicated grief, which includes discussing certain aspects of the death of a loved one, was found more effective than a standard therapy for depression, according to a study in the June 1 issue of JAMA.

25 May 2005

Investigational device-based therapies will lead to entirely new treatment options for chronic depression sufferers

Researchers said that developing brain stimulation techniques such as transcranial magnetic stimulation (TMS), vagal nerve stimulation and deep brain stimulation are emerging as significant treatment options for the millions of patients "poorly served" by existing therapies.

23 May 2005

Magnetic stimulation treatment for depression

Barbara Baas ran away from home and tried to kill herself as a teenager. As an adult, she has tried more than 15 varieties of antidepressants. But, thanks to a new weapon, she has finally reached a truce in a 45-year battle.

10 May 2005