Malignant News and Research

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First evidence of the molecular link between inflammation and cancer

The investigators found that a gene called I-kappa-B kinase (IKK beta), a pro-inflammatory gene, acts differently in two cell types to cause cancer. When IKK beta was deleted, the cancer incidence and tumor growth in mice was decreased by nearly 80 percent.

5 Aug 2004

PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures

A new study using positron emission tomography (PET) determined PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures.

5 Aug 2004

Smart drug that targets cancer cells in the brain following removal of a tumor

The use of a "smart" drug that targets cancer cells in the brain following removal of a tumor may provide treatment that can extend the survival of people with the most common form of primary malignant brain tumor, glioblastoma multiforme (GBM).

3 Aug 2004

Successfully cloning mice from an advanced melanoma cell

Nature can reset the clock in certain types of cancer and reverse many of the elements responsible for causing malignancy, reports a research team led by Whitehead Institute Member Rudolf Jaenisch, in collaboration with Lynda Chin from Dana Farber Cancer Institute.

3 Aug 2004

New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients

Experts on the Gene Therapy Advisory Committee have given the go ahead for a large clinical trial of a new treatment for patients with Glioma - one of the most aggressive types of brain tumours for which there is currently no cure.

3 Aug 2004

New approach to cancer vaccines may eradicate skin cancer tumors

Mayo Clinic and British researchers have developed a new approach to cancer vaccines that purposely kills healthy skin cells to target the immune system against tumors. The new approach has eradicated skin cancer tumors in mice.

2 Aug 2004

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Eli Lilly and Company have announced that the Oncologic Drugs Advisory Committee (ODAC) of the U.S. Food and Drug Administration positively endorsed Alimta® (pemetrexed), an antifolate, for accelerated approval in the second-line treatment of non-small cell lung cancer.

29 Jul 2004

Innovative treatment for cancer patients who have previously undergone chemotherapy, surgery or radiotherapy

At the inauguration of Hadassah's new day care center of the Sidney Weisner Department of Bone Marrow Transplantation and Cancer Immunotherapy today, Prof. Shimon Slavin, head of the department, described an innovative treatment for cancer patients who have previously undergone chemotherapy, surgery and/ or radiotherapy.

26 Jul 2004

Chemotherapy aimed at both cancer cells and their genetically normal cellular 'microenvironment' might improve the success of breast cancer treatment

In the first comprehensive survey of gene activity in each cell type composing normal and malignant breast tissue, scientists at Dana-Farber Cancer Institute have identified genes in non-cancerous supporting cells that can spur the growth of breast cancer cells.

20 Jul 2004

Effective treatment for soft tissue sarcoma (rhabdomyosarcoma)

Rhabdomyosarcoma is a highly malignant aggressive form of soft tissue cancer in children, the causes of which are currently unknown. Although the fibrous growths can be found all over the body they commonly develop around the head, neck, bladder and testes in young boys.

15 Jul 2004

Surgical flight syndrome: how to reduce the risks

“Most people know that all surgery carries some risk,” says Peter Fodor, President of the American Society for Aesthetic Plastic Surgery (ASAPS). “What is less well known is that airline travel carries risk. So people who combine the two need to take extra precautions,” he says.

15 Jul 2004

Targeted therapeutics capable of preventing or limiting the metastasis of skin cancer

An international team of scientists has identified an important molecular link involved in the spread – or metastasis – of melanoma to other organs such as the lungs.

15 Jul 2004

Research that directs cancer-killing immune cells against the deadliest brain tumors shows promise

Researchers seeking to direct cancer-killing immune cells against the deadliest brain tumors have three new targets that show promise in laboratory studies and in a Phase I patient trial, according to two articles in the July 15 issue of the journal Cancer Research.

15 Jul 2004

Important milestone for any cancer therapy that will be useful for treating patients

Mayo Clinic researchers have manipulated a human antibody to induce an anti-tumor response in living mice that consistently curbs - and often cures - malignant melanoma, one of the most lethal forms of skin cancer and the most common cancer of young adults.

15 Jul 2004

Thalidomide's role in fighting blood disorders, such as multiple myeloma

From the late 1950s to the end of 1961, thalidomide was a popular sedative and treatment for morning sickness until it was discovered to cause fetal malformations, which proved fatal within the first year of life in 40 percent of affected infants.

13 Jul 2004

FDA approval for computer aided detection (CAD) software to analyze CT images

The Food and Drug Administration has approved a new image analysis system designed to help radiologists review computed tomography (CT) images of the chest to aid in the detection of solid nodules in the lungs.

13 Jul 2004

Skeletal remains of 3,160 individuals reveal changing status of cancer in Europe across the centuries

Cancer incidence rates in the developed world are increasing each year and developing countries are also now showing an increased incidence of the disease.

8 Jul 2004

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Researchers at the University of California, San Diego (UCSD) School of Medicine have determined that a particular type of cellular stress called osmotic stress is of critical importance to cell growth and the body’s immune response against infection.

7 Jul 2004

Children cured of acute lymphocytic leukemia after chemotherapy have a 5-20 times greater risk of developing secondary malignant neoplasm's

The alterations in the children's gene sequence remain embedded within their chromosomes and may pose elevated risk for development of second malignancies and other diseases later in life, cautioned Barry A. Finette, M.D., Ph.D., associate professor of pediatrics at the University of Vermont.

1 Jul 2004

Four most common cancers accounted for over half of the 225,000 new cases of malignant cancer registered in England in 2001

The four most common cancers - breast, lung, colorectal and prostate - accounted for over half of the 225,000 new cases of malignant cancer (excluding non-melanoma skin cancer) registered in England in 2001.

30 Jun 2004

Malignant News and Research

First evidence of the molecular link between inflammation and cancer

PET is a more accurate way to diagnose recurrent melanoma than the present, standard procedures

Smart drug that targets cancer cells in the brain following removal of a tumor

Successfully cloning mice from an advanced melanoma cell

New gene therapy treatment involves injecting Herpes simplex virus into the brain tumours of Glioma patients

New approach to cancer vaccines may eradicate skin cancer tumors

Alimta receives positive endorsement for lung cancer approval from FDA Advisory Committee

Innovative treatment for cancer patients who have previously undergone chemotherapy, surgery or radiotherapy

Chemotherapy aimed at both cancer cells and their genetically normal cellular 'microenvironment' might improve the success of breast cancer treatment

Effective treatment for soft tissue sarcoma (rhabdomyosarcoma)

Surgical flight syndrome: how to reduce the risks

Targeted therapeutics capable of preventing or limiting the metastasis of skin cancer

Research that directs cancer-killing immune cells against the deadliest brain tumors shows promise

Important milestone for any cancer therapy that will be useful for treating patients

Thalidomide's role in fighting blood disorders, such as multiple myeloma

FDA approval for computer aided detection (CAD) software to analyze CT images

Skeletal remains of 3,160 individuals reveal changing status of cancer in Europe across the centuries

Type of cellular stress called osmotic stress is critical to cell growth and the body’s immune response against infection

Children cured of acute lymphocytic leukemia after chemotherapy have a 5-20 times greater risk of developing secondary malignant neoplasm's

Four most common cancers accounted for over half of the 225,000 new cases of malignant cancer registered in England in 2001

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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