Mast Cell News and Research

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Cells linked to asthma and eczema also help cure deadly illness in mice

Mast cells are immune cells known mostly for their unwanted effects: they cause the wheezing of asthma, the itching of eczema, the sneezing and runny nose of hay fever and, in extreme cases, the life-threatening shock of anaphylaxis.

20 Nov 2004

Mast cells can provide protection from a potentially deadly condition known as sepsis

14 Nov 2004

Researchers identify a protein that could banish allergies

The suffering of millions of people with allergies could one day be eased thanks to new research from UK investigators. Findings from the University College London branch of the Ludwig Institute for Cancer Research (LICR), published in the Oct 2004 issue of Nature, detail how inactivating a key signalling molecule called p110delta reduced the effect of allergies on mice.

21 Oct 2004

Australian researchers hunt for eczema genes

The Queensland Institute of Medical Research (QIMR) is halfway through a major project examining possible genetic causes of atopic dermatitis which is the most common form of eczema.

6 Oct 2004

Research will lead to better treatments for mastocytosis

Tens of millions of people know what it's like to suffer the seasonal torment of allergies, when just a whiff of pollen, mold or dust can set off a chain reaction in the body that causes sniffling, sneezing and coughing.

18 Aug 2004

Forward step in treatment of Allergic Rhinitis

Rigel Pharmaceuticals, Inc. has announced the presentation of clinical data for R112, the company’s lead candidate for the treatment of allergic rhinitis, during a poster session at the annual meeting of the American Academy of Allergy, Asthma and Immunology (AAAAI) in San Francisco, CA. The phase I/II single dose trial demonstrated that R112 was well tolerated and showed favorable biological effects.

22 Mar 2004