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Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

Researchers at the National Institutes of Health have published an atlas of zebrafish development, detailing the gene expression programs that are activated within nearly every cell type during the first five days of development, a period in which embryos mature from a single cell into distinct cell types.

18 Dec 2023

New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

$9M awarded to study HIV and substance use at intersection of vulnerable populations

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine (UMSOM) received an annual award for $3 million funded by the NIH Office of AIDS Research.

15 Dec 2023

Urgent need for action as vaping spreads through social media

A University of Queensland research project will investigate the online influences behind young people taking up vaping, and develop social media content to support them in quitting the habit.

15 Dec 2023

UMSOM secures $7.3 million DARPA funding to better optimize the triage of patients during mass casualty events

In an effort to better optimize the triage of patients during mass casualty events, University of Maryland School of Medicine (UMSOM) researchers are receiving up to $7.3 million in funding from the Defense Advanced Research Project Agency (DARPA) for vital new research.

15 Dec 2023

UCL researchers develop new gene therapy to cure severe childhood epilepsy

UCL researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which a new study shows can significantly reduce seizures in mice.

14 Dec 2023

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, and colleagues.

14 Dec 2023

The impact of racism on mental health disparities experienced by Black people in the United States

A series of literature reviews published online December 13 in The Lancet Psychiatry journal highlight the large body of evidence on the role played by racism in mental health disparities experienced by Black people living in the United States.

14 Dec 2023

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies.

14 Dec 2023

Deep learning reveals hidden patterns in adolescent mental health

The personal yet global struggle with mental health may be more visible now than ever before. Yet many people still find it difficult to access the support they need. In Japan, suicide is sadly the leading cause of death for young people.

13 Dec 2023

People with very irregular sleep patterns may have higher dementia risk

People who have very irregular sleep patterns may have a higher risk of dementia than those who have more regular sleep patterns, according to new research published in the December 13, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

13 Dec 2023

Weill Cornell Medicine joins PICI network for collaborative cancer research effort

The Parker Institute for Cancer Immunotherapy (PICI), the largest concentration of immuno-oncology (IO) expertise in the world, announced it has added Weill Cornell Medicine to its network of preeminent academic and medical research institutions at the forefront of the fight against cancer.

13 Dec 2023

Protective genetic variant shields Black Americans from kidney disease risk

Many Black Americans who are thought to have a high risk of developing kidney disease possess a protective genetic variant that nullifies the extra risk, a new study from Columbia researchers has found.

12 Dec 2023

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

Published in The Lancet's eBioMedicine, 76 healthy adults from Melbourne, aged 18 to 64 who were previously vaccinated with licensed SARS-CoV-2 vaccines, were randomized to receive a fourth dose of a novel protein vaccine, mRNA vaccine or placebo.

12 Dec 2023

UVA atlas unveils cellular blueprint of atherosclerosis

University of Virginia School of Medicine researchers have created an "atlas of atherosclerosis" that reveals, at the level of individual cells, critical processes responsible for forming the harmful plaque buildup that causes heart attacks, strokes and coronary artery disease.

12 Dec 2023

New study unlocks hope for immunotherapy in metastatic prostate cancer

Immunotherapy has been disappointing as a prostate cancer treatment, but a new Columbia study suggests that the powerful treatments have potential when the disease starts to spread.

12 Dec 2023

Research reimagined: Online platform empowers patients and professionals to set rare disease priorities

Patients with rare diseases have traditionally been the subjects of medical research. However, in recent years, their role has begun to shift from 'research participants' to 'experts with a lived experience', with some being involved in study planning, design and interpretation.

11 Dec 2023

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

The Malaghan Institute of Medical Research in collaboration with Wellington Zhaotai Therapies Limited today announced results of its phase 1 dose escalation trial of a new third-generation anti-CD19 chimeric antigen receptor (CAR) T-cell therapy to be presented at the American Society of Hematology (ASH) Annual Meeting in San Diego on 11 December, 3pm.

11 Dec 2023

UMSOM receives $29 million research award to improve health outcomes in people who inject opioid drugs

University of Maryland School of Medicine Dean Mark T. Gladwin, MD, announced today that the school will receive a $29 million research award over four years from the National Institutes of Health to lead a multicenter trial that aims to improve health outcomes in people who inject opioid drugs and are hospitalized with infectious complications of their drug use.

11 Dec 2023

Research uncovers potential treatment target for rare, genetic type of epilepsy

Researchers at the Francis Crick Institute, UCL and MSD have identified a potential treatment target for a genetic type of epilepsy.

11 Dec 2023

Medical Research News and Research

Single-cell RNA sequencing generates comprehensive atlas of zebrafish development

New discovery could expand the possibilities for medical use of Botox

$9M awarded to study HIV and substance use at intersection of vulnerable populations

Urgent need for action as vaping spreads through social media

UMSOM secures $7.3 million DARPA funding to better optimize the triage of patients during mass casualty events

UCL researchers develop new gene therapy to cure severe childhood epilepsy

NIAID study identifies critical T-cell function missing in prior HIV vaccine candidates

The impact of racism on mental health disparities experienced by Black people in the United States

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Deep learning reveals hidden patterns in adolescent mental health

People with very irregular sleep patterns may have higher dementia risk

Weill Cornell Medicine joins PICI network for collaborative cancer research effort

Protective genetic variant shields Black Americans from kidney disease risk

RBD-focused vaccines may offer broader protection against emerging COVID-19 variants

UVA atlas unveils cellular blueprint of atherosclerosis

New study unlocks hope for immunotherapy in metastatic prostate cancer

Research reimagined: Online platform empowers patients and professionals to set rare disease priorities

Double punch for B-cell lymphomas: CAR T-cell innovation boosts efficacy, cuts toxicity

UMSOM receives $29 million research award to improve health outcomes in people who inject opioid drugs

Research uncovers potential treatment target for rare, genetic type of epilepsy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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