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Cipla, DNDi to develop ARV combination therapy for children with HIV/AIDS

On the eve of the XIX International AIDS Conference in Washington, DC, the Drugs for Neglected Diseases initiative (DNDi), a not-for-profit research and development (R&D) organization, announces a new collaboration with Indian drug manufacturer Cipla to develop and produce an improved first-line antiretroviral (ARV) combination therapy specifically adapted to meet the treatment needs of infants and toddlers living with HIV/AIDS.

21 Jul 2012

Maternal fat indicates birthweight

Measuring hip circumference during pregnancy may help to predict a child’s size at birth, report Canadian researchers.

20 Jul 2012

Scientists identify inhibitors of key enzyme involved in survival of malaria parasite

An international team of scientists, led by researchers from the Department of Pediatrics at the University of California, San Diego School of Medicine, have identified the first reported inhibitors of a key enzyme involved in survival of the parasite responsible for malaria. Their findings, which may provide the basis for anti-malarial drug development, are currently published in the online version of the Journal of Medicinal Chemistry.

20 Jul 2012

Roundup: Ore. issues new long-term care insurance claims rules; Fla. pushing ahead with prison care privatization

The Oregon Insurance Division receives about 100 complaints about long-term-care policies each year, mostly about delays or denials. But now the state's role is increasing, thanks to a law that went into effect this month. The Oregon law requires insurers to process long-term care claims within 30 days when they're not in dispute. It also allows outside review when an insurer decides a person isn't sufficiently disabled for long-term care.

19 Jul 2012

Polio eradication: an interview with Dr. Kathleen O’Reilly

Polio is a disease caused by a virus and results in paralysis, usually in the legs, of those affected. The paralysis is irreversible. In some extreme cases the virus spreads to the nerve cells of the brain reducing breathing capacity and this rarer form can be fatal.

16 Jul 2012

Johns Hopkins doctoral program graduate explores ways to control infectious diseases

Her passport is stamped with exotic locations: Myanmar, Tibet, South Africa, Vietnam, and Cambodia, as well as Baltimore, MD. But, when Carrie Tudor, PhD, MPH, RN, looks at it, she sees global battlefields in the fight against infectious disease. Her weapons: immunizations, programs to curb tuberculosis and HIV transmission, and a drive to carry on a rich tradition of public health nursing research.

16 Jul 2012

Scientists clone tannin gene in sorghum

They might be called a blessing or a curse -- tannins, which are present in certain sorghums, contain health-promoting antioxidant properties, but also provide a bitter taste and decreased protein digestibility. To better understand tannins, their role in sorghum and how they can be altered to improve sorghum's use as food and feed, a team of scientists led by Kansas State University and U.S. Department of Agriculture researchers, has cloned the tannin gene in sorghum.

14 Jul 2012

AOSSM to present ten research awards and seven grants during annual meeting in Baltimore

In order to recognize and encourage cutting-edge research in key areas of orthopaedic sports medicine, the American Orthopaedic Society for Sports Medicine (AOSSM) will present ten research awards and seven grants during its Annual Meeting, July 12-15 in Baltimore, MD. As a leader in orthopaedic sports medicine, AOSSM annually provides more than $350,000 to research initiatives and projects around the country.

12 Jul 2012

Mayo Clinic, 18 other leading research institutions urge Congress to maintain funding levels for NIH

Mayo Clinic and 18 other leading medical research institutions nationwide are urging congressional leaders to maintain current funding levels for the National Institutes of Health.

12 Jul 2012

New drug combination could offer hope to children with neuroblastoma

A new drug combination could offer hope to children with neuroblastoma - one of the deadliest forms of childhood cancer - by boosting the effectiveness of a promising new gene-targeted treatment.

12 Jul 2012

IntNSA, Wolters Kluwer partner to publish Journal of Addictions Nursing

Wolters Kluwer Health and International Nurses Society on Addictions (IntNSA) are pleased to announce a partnership agreement to publish Journal of Addictions Nursing (JAN), the official journal of IntNSA. Lippincott Williams & Wilkins (LWW), part of Wolters Kluwer Health, will be the publisher of record for Journal of Addictions Nursing (JAN), beginning with the October 2012 issue.

12 Jul 2012

Thrombopoietin mimetic offers aplastic anemia hope

Eltrombopag significantly improves blood counts in some patients with refractory severe aplastic anemia, suggests research published in The New England Journal of Medicine.

11 Jul 2012

HIV and AIDS treatment: An interview with Charles Flexner, MD

The best estimates at the moment reckon that there are about 25 million people infected with HIV. Most of those are in resource-limited settings, including sub-Saharan Africa, South East Asia and India.

11 Jul 2012

SRI International receives DoD grant to develop novel therapy for MS

The Department of Defense (DoD) has awarded SRI International a one-year grant to develop a novel therapy for multiple sclerosis (MS), an autoimmune nervous system disease that affects about 400,000 people in the United States and more than two million people worldwide. There is currently no cure for this disorder, which can impair vision and movement.

11 Jul 2012

Methylation provides signal of unique mix of leukocytes

When a person is sick, there is a tell-tale sign in their blood: a different mix of the various types of immune cells called leukocytes. A group of scientists at several institutions including Brown University has discovered a way to determine that mix from the DNA in archival or fresh blood samples, potentially providing a practical new technology not only for medical research but also for clinical diagnosis and treatment monitoring of ailments including some cancers.

10 Jul 2012

U-M to receive CTSA grant renewal in support of clinical and translational research

University of Michigan scientists and doctors do some of the most advanced medical research in the world. But much of it wouldn't be possible without the thousands of people a year who volunteer their time, health information, blood, saliva, DNA or other samples to help those researchers better understand diseases and improve health outcomes.

10 Jul 2012

Targeting double-stranded RNA dependent protein kinase could treat inflammation

Researchers at The Feinstein Institute for Medical Research have discovered that inflammation could be treated by targeting a molecule called the double-stranded RNA dependent protein kinase (PKR). These findings are published in the July issue of Nature.

9 Jul 2012

Scientists train visually impaired to perform fast and accurate movements using EyeMusic

Sensory substitution devices (SSDs) use sound or touch to help the visually impaired perceive the visual scene surrounding them. The ideal SSD would assist not only in sensing the environment but also in performing daily activities based on this input.

6 Jul 2012

Reprogramming asthma-promoting immune cells diminishes airway damage and inflammation

Reprogramming asthma-promoting immune cells in mice diminishes airway damage and inflammation, and could potentially lead to new treatments for people with asthma, researchers have found.

5 Jul 2012

Scientists reprogram amniotic fluid cells without introduction of extra genes

Stem cells found in amniotic fluid can be transformed into a more versatile state similar to embryonic stem cells, according to a study published today in the journal Molecular Therapy. Scientists from Imperial College London and the UCL Institute of Child Health succeeded in reprogramming amniotic fluid cells without having to introduce extra genes.

4 Jul 2012

Medical Research News and Research

Cipla, DNDi to develop ARV combination therapy for children with HIV/AIDS

Maternal fat indicates birthweight

Scientists identify inhibitors of key enzyme involved in survival of malaria parasite

Roundup: Ore. issues new long-term care insurance claims rules; Fla. pushing ahead with prison care privatization

Polio eradication: an interview with Dr. Kathleen O’Reilly

Johns Hopkins doctoral program graduate explores ways to control infectious diseases

Scientists clone tannin gene in sorghum

AOSSM to present ten research awards and seven grants during annual meeting in Baltimore

Mayo Clinic, 18 other leading research institutions urge Congress to maintain funding levels for NIH

New drug combination could offer hope to children with neuroblastoma

IntNSA, Wolters Kluwer partner to publish Journal of Addictions Nursing

Thrombopoietin mimetic offers aplastic anemia hope

HIV and AIDS treatment: An interview with Charles Flexner, MD

SRI International receives DoD grant to develop novel therapy for MS

Methylation provides signal of unique mix of leukocytes

U-M to receive CTSA grant renewal in support of clinical and translational research

Targeting double-stranded RNA dependent protein kinase could treat inflammation

Scientists train visually impaired to perform fast and accurate movements using EyeMusic

Reprogramming asthma-promoting immune cells diminishes airway damage and inflammation

Scientists reprogram amniotic fluid cells without introduction of extra genes

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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