Medicinal Chemistry News and Research

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New type of vaccine targets deadly tuberculosis

Australian medical researchers from the Centenary Institute and the University of Sydney have successfully developed and tested a new type of vaccine targeting tuberculosis (TB), the world's top infectious disease killer.

25 Aug 2019

Weak electron attraction helps hold together amyloid beta sheets found in Alzheimer's

The chemical interactions that give proteins their shape may be weaker and more numerous than previously recognized. These weak connections provide a new way for researchers to understand proteins that cause disease and help them gain insights into the fundamentals of chemistry.

24 Jul 2019

Researchers develop new compound to block therapeutic target in aggressive blood cancer

Researchers at the UNC Lineberger Comprehensive Cancer Center have discovered a hyperactive cell signal that contributes to tumor growth in an aggressive blood cancer.

23 Jul 2019

Researchers open the door to a new era of medicinal chemistry

Progress in the pharmaceutical industry depends largely on the achievements and advances in medicinal chemistry.

14 Jul 2019

Novel anticancer agents show promise to control tumor growth in nearly every cancer type

A gene called MYC has become one of the hottest targets for cancer researchers around the world. MYC is known to drive tumor growth in nearly all cancer types - but successfully targeting the gene has proven to be a challenge.

9 Jul 2019

New technology could improve surgical outcomes for cancer patients

A study led by researchers at RCSI's Department of Chemistry has the potential to help surgeons more accurately remove tumors and detect cancer in lymph nodes during surgery.

8 Jul 2019

Researchers develop technique to track proteins on the surfaces of endoplasmic reticulum in cells

Researchers from Kanazawa University on the development of a technique to closely track a specific protein on the surfaces of endoplasmic reticulum (ER) in cells. Their findings are published in Bioorganic and Medicinal Chemistry.

17 Jun 2019

Boehringer Ingelheim and University of Dundee extend collaboration to develop new cancer medicines

Following the success of their ongoing alliance, Boehringer Ingelheim and the University of Dundee extend their collaboration to develop new medicines that target and destroy key cancer causing proteins.

12 Jun 2019

Chemists build rich collection of natural product-like macrocycles for drug discovery

Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class.

12 Jun 2019

Scientific discovery may lead to a treatment for lupus

A team of scientists has uncovered the structure of a regulatory complex that is involved in the release of cytokines and can be inhibited to treat lupus.

31 May 2019

Marine natural compounds could be potential treatments for triple negative breast cancer

The oceans cover more than 70 percent of the earth's surface and provide a rich source of unique, bioactive natural products.

17 May 2019

Recombinant insulin could potentially address key concerns about the lifesaving drug

A researcher from the University of Houston has created a form of recombinant insulin that could potentially address some of the biggest concerns about the lifesaving drug, including its price.

16 May 2019

New drug minimizes damage after a heart attack by 60 percent

Scientists have found a potential new drug for treating the heart damage caused by a heart attack by targeting the way the heart reacts to stress.

From Domainex 25 Apr 2019

Researchers create new small molecules that may combat equine encephalitis viruses

Viruses without a preventative vaccine or treatment option pose a looming threat. But for viruses in this category that have already been weaponized and are recognized as human biothreats by the Centers for Disease Control and Prevention, it's a race to find a cure.

17 Apr 2019

GARDP forms multi-actor partnerships to discover new antibiotics

Multi-actor partnership tests natural products and compound libraries for antibacterial activity Discovery efforts will focus on World Health Organization's priority pathogens The Global Antibiotic Research and Development Partnership is partnering with Calibr, the Helmholtz Centre for Infection Research, in particular its location Helmholtz-Institute for Pharmaceutical Research Saarland, and the University of Queensland's Community for Open Antimicrobial Drug Discovery in its efforts to develop and ensure new antibiotics are globally available to all patients who need them.

11 Apr 2019

Researchers aim to identify potential new drugs for wide range of diseases using AI

A half dozen University of Connecticut researchers are now working to identify potential new drugs to treat a wide range of diseases and conditions through a unique partnership that offers access to cutting-edge artificial intelligence technology and screening compounds at no cost.

10 Apr 2019

Medicinal Chemistry News and Research

New type of vaccine targets deadly tuberculosis

Weak electron attraction helps hold together amyloid beta sheets found in Alzheimer's

Researchers develop new compound to block therapeutic target in aggressive blood cancer

Researchers open the door to a new era of medicinal chemistry

Novel anticancer agents show promise to control tumor growth in nearly every cancer type

New technology could improve surgical outcomes for cancer patients

Researchers develop technique to track proteins on the surfaces of endoplasmic reticulum in cells

Boehringer Ingelheim and University of Dundee extend collaboration to develop new cancer medicines

Chemists build rich collection of natural product-like macrocycles for drug discovery

Scientific discovery may lead to a treatment for lupus

Marine natural compounds could be potential treatments for triple negative breast cancer

Recombinant insulin could potentially address key concerns about the lifesaving drug

New drug minimizes damage after a heart attack by 60 percent

Researchers create new small molecules that may combat equine encephalitis viruses

GARDP forms multi-actor partnerships to discover new antibiotics

Researchers aim to identify potential new drugs for wide range of diseases using AI

Researchers isolate compound that kills drug-resistant fungi from ant microbiota

New class of molecules could someday become basis for Zika-specific therapeutic

Promising new way to thwart tricky Mtb pathogen

Enamine and Lundbeck announce expansion of drug discovery collaboration

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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