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Genetic mutation that helps regulate high blood pressure is a cause of inherited kidney disease

The discovery provides insight into a protein, renin, that is important in blood pressure regulation, and reveals the cause of one type of inherited kidney disease occurring in adults and children, said co-investigator Anthony Bleyer, M.D., professor of internal medicine-nephrology at the School of Medicine.

19 Aug 2009

New data show nanotechnology-related activities in every U.S. state

Every state can now lay claim to the nanotechnology revolution. Data released today by the Project on Emerging Nanotechnologies (PEN) highlights more than 1,200 companies, universities, government laboratories, and other organizations across all 50 U.S. states and in the District of Columbia that are involved in nanotechnology research, development, and commercialization. This number is up 50 percent from the 800 organizations identified just two years ago.

19 Aug 2009

Kolltan Pharmaceuticals raises additional $5 million to close Series A financing

Kolltan Pharmaceuticals, Inc. announced today that it has raised an additional $5 million to close its Series A preferred stock financing at $40 million. Participants in the Series A financing, originally announced in January 2009, include Purdue Pharma, L.P., HBM BioCapital L.P., the Pritzker/Vlock family, and other substantial private life science investors.

19 Aug 2009

Solta Medical launches new Thermage Comfort Pulse Technology system

Solta Medical, Inc. (Nasdaq: SLTM) today announced the launch of its new Thermage CPT(TM) system, representing a significant leap forward in skin tightening and body contouring technology. The Thermage CPT system incorporates proprietary Comfort Pulse Technology(TM) in every aspect of the system including a new ergonomic vibrating hand piece and scientifically advanced Face Tip 3.0 and Body Tip 16.0 treatment tips.

19 Aug 2009

IVF treatment not to be combined with alternative therapies

Women who are desperately trying to get pregnant might want to avoid complementary and alternative medicine. The common belief is that it won't hurt to try alternative fertility treatments before reverting to in vitro fertilization (IVF). But a new study from Denmark finds that the success of IVF treatment is 30% lower among women who have used alternative medicine.

19 Aug 2009

Young innovators Andrea Armani and Ellis Meng to feature in Technology Review magazine's 2009 TR35 list

The University of Southern California today announced that two faculty members from the USC Viterbi School of Engineering have been recognized by Technology Review magazine as some of the world's top innovators under the age of 35. Andrea Armani, Assistant Professor of Chemical Engineering and Materials Science, and Ellis Meng, Assistant Professor of Biomedical Engineering, will both appear on the prestigious 2009 TR35 list.

19 Aug 2009

New understanding on meningitis cause

A specific protein on the surface of a common bacterial pathogen allows the bacteria to leave the bloodstream and enter the brain, initiating the deadly infection known as meningitis. The new finding, which may guide development of improved vaccines to protect those most vulnerable, including young infants and the elderly, is now available online in the Journal of Experimental Medicine.

19 Aug 2009

Discovery of key factor that stimulates brain cancer cells to spread

Researchers funded by the National Institutes of Health have found that the activity of a protein in brain cells helps stimulate the spread of an aggressive brain cancer called glioblastoma multiforme (GBM). In a move toward therapy, the researchers showed that a small designer protein can block this activity and reduce the spreading of GBM cells grown in the laboratory.

19 Aug 2009

Low-dose estrogen effective for metastatic breast cancer

When estrogen-lowering drugs no longer control metastatic breast cancer, the opposite strategy might work. Raising estrogen levels benefited 30 percent of women whose metastatic breast cancer no longer responded to standard anti-estrogen treatment, according to research conducted at Washington University School of Medicine in St. Louis and collaborating institutions.

19 Aug 2009

Texas Public Policy Foundation says health plans would cause more harm than good

The health care reform plans pending in the U.S. Congress would cause more harm than good, according to a study released today by the Texas Public Policy Foundation.

19 Aug 2009

Bloomberg reports on HIV-treatment failure in China; New York Times examines ARV shortage in Romania

An analysis of 48,785 HIV-positive patients enrolled in China's National Free Antiretroviral Treatment Program over a five-year period revealed that "[h]alf of China's AIDS patients stopped responding to treatment over five years and didn't have access to the back-up drugs available in developed nations," according to an Annals of Internal Medicine study, Bloomberg reports.

19 Aug 2009

Nonsurgical, quick and accurate test for diagnosing endometriosis discovered

A quick and accurate test for endometriosis that does not require surgery has been developed by researchers from Australia, Jordan and Belgium, according to new research published online today (Wednesday 19 August) in Europe's leading reproductive medicine journal Human Reproduction.

19 Aug 2009

Study shows lower short-term mortality rates in patients hospitalized for AMI

From 1995 to 2006, hospital 30-day death rates decreased significantly for Medicare patients hospitalized for a heart attack, as did the variation in the rate between hospitals, according to a study in the August 19 issue of JAMA.

19 Aug 2009

Cost of physician reimbursement for diabetic leg amputations misconstrued

The cost of doctors performing lower-limb amputations for people with diabetes has been misconstrued during recent health care reform discussions, according to the American Podiatric Medical Association (APMA).

19 Aug 2009

New software programs improve the cancer biomarker identification process

caCORRECT and omniBioMarker programs earn silver-level compatibility certification from NIH/National Cancer Institute's cancer Bioinformatics Grid

19 Aug 2009

Cyanide toxicity in smoke inhalation victims

"If commercial flying had as many civilian fatalities as those relating to smoke and fire, there would be a public revolt," said Rob Schnepp, CPTC president and assistant chief of special operations for the Alameda County Fire Department in California. "The numbers aren't going down, and this tells me that we aren't addressing the problem adequately.

18 Aug 2009

Weight training reduces lymphedema symptoms after breast cancer surgery

Breast cancer survivors who lift weights are less likely than their non-weightlifting peers to experience worsening symptoms of lymphedema, the arm- and hand-swelling condition that plagues many women following surgery for their disease, according to new University of Pennsylvania School of Medicine research published in the August 13 issue of the New England Journal of Medicine.

18 Aug 2009

Video-game playing and health risks

While video gaming is generally perceived as a pastime for children and young adults, research shows that the average age of players in the United States is 35.

18 Aug 2009

Disrupting the DNA-repair process

Scientists at Dana-Farber Cancer Institute have uncovered the mechanism behind a promising new approach to cancer treatment: damaging cancer cells' DNA with potent drugs while simultaneously preventing the cells from repairing themselves.

18 Aug 2009

Novel genome-analysis strategy to speed search for gene-disease links

University of Washington (UW) researchers have successfully developed a novel genome-analysis strategy for more rapid, lower cost discovery of possible gene-disease links. By saving time and lowering expenses, the approach makes it feasible for scientists to search for disease-causing genes in people with the same inherited disorder but without any family ties to each other.

18 Aug 2009