Metabolic Disease News and Research

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Researchers identify a single protein that balances sugar and fat metabolism in the liver

Keeping everything running smoothly inside the human body is a tricky business that involves a multitude of checks and balances to make sure that an exquisite equilibrium is maintained.

2 Nov 2021

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

A group of researchers from various institutes in the USA addressed the limitations of BAT therapy by transplanting a low dose of brown adipocytes (BAs) without Matrigel to determine if this could alleviate high-fat diet-induced OB, metabolic symptoms, and T2DM in mice.

18 Oct 2021

High fat diet exacerbates Alzheimer's disease in mouse model

Research has shown that individuals who have diabetes are more prone to develop dementia. Although people are widely aware of diabetes, owing to its common occurrence, they are less aware of prediabetes. Similar to diabetes, prediabetes is also associated with impaired glucose tolerance. However, unlike diabetes, patients with prediabetes show a slight increase in insulin and fasting blood glucose rather than hyperglycemia.

7 Oct 2021

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Researchers at Johns Hopkins Medicine have found that a drug first developed to treat Alzheimer's disease, schizophrenia and sickle cell disease reduces obesity and fatty liver in mice and improves their heart function — without changes in food intake or daily activity.

7 Oct 2021

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

A study published in the journal Clinical Nutrition provides new knowledge on the health effects of a diet rich in nuts.

7 Oct 2021

Managing metabolic disease through time-restricted eating

In this interview, News-Medical speaks to Dr. Satchin Panda about his latest research into time-restricted eating and how it can be used to manage metabolic diseases.

5 Oct 2021

Standing is associated with better insulin sensitivity and metabolic health

Insulin is a key hormone in energy metabolism and blood sugar regulation. Normal insulin function in the body may be disturbed by e.g. overweight, leading to decreased insulin sensitivity and increased risk of developing type 2 diabetes and cardiovascular diseases.

12 Sep 2021

Age and sex affect the outcomes of time-restricted eating

Time-restricted eating (TRE), a dietary regimen that restricts eating to specific hours, has garnered increased attention in weight-loss circles.

17 Aug 2021

Women incur significant out-of-pocket expenses for managing diabetes, finds study

Women with diabetes incur significant out-of-pocket expenses to manage their health, with the costs rising the longer they have the disease, a new study has found.

17 Aug 2021

Study finds novel approach to attenuate mitochondrial dysfunction that drives diet-induced obesity

A team of University of California, Irvine, scientists have discovered a novel pharmacological approach to attenuate the mitochondrial dysfunction that drives diet-induced obesity.

12 Aug 2021

Surplus sugar may cause our cellular powerplants to become less efficient, finds study

The average American eats roughly 22 teaspoons of added sugar a day -; more than three times the recommended amount for women and more than double the recommended amount for men.

3 Aug 2021

Simple method to assess the risk of vascular inflammation for diabetes patients

A team of international scientists from Nanyang Technological University, Singapore (NTU Singapore), Tan Tock Seng Hospital (TTSH) in Singapore, and the Massachusetts Institute of Technology (MIT) has developed a simple method of extracting tiny biological particles from a person's blood and use them as biomarkers to assess the health of their blood vessels.

27 Jul 2021

Detailed performance evaluation of the uEXPLORER total-body PET/CT scanner

A performance evaluation of the uEXPLORER total-body PET/CT scanner showed that it exhibits ultra-high sensitivity that supports excellent spatial resolution and image quality.

8 Jul 2021

Western diet increases COVID-19 severity in a hamster model

Researchers have shown that a Western diet may affect viral replication, disease severity, and immune protection following infection with SARS-CoV-2.

21 Jun 2021

Change in diet and circadian clock can impact healthy fat tissue, finds study

Changing your eating habits or altering your circadian clock can impact healthy fat tissue throughout your lifespan, according to a preclinical study published today in Nature by researchers with The University of Texas Health Science Center at Houston.

15 Jun 2021

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Researchers have developed a new approach to gene therapy that leans on the common pain reliever acetaminophen to force a variety of genetic diseases into remission.

14 Jun 2021

Virginia Tech researcher receives $2.2 million to advance study on small 'fat burning' molecules

The liver is the most resilient organ in the human body. It can remove toxins from the bloodstream, recycle red blood cells, maintain sugar levels, and it can even regenerate itself. But, when a large amount of fat builds up in the liver, it becomes too inflamed to perform its crucial duties.

14 Jun 2021

Study confirms the importance of low-protein, high-carbohydrate diet

Researchers at the University of Sydney's Charles Perkins Centre conducted the largest ever study of nutrient interactions by examining the health of mice on 33 different diets containing various combinations of protein to carbs, and different sources of carbohydrate.

8 Jun 2021

Simple dietary supplement ameliorates schizophrenic traits in mice

A simple dietary supplement reduces behavioral symptoms in mice with a genetic mutation that causes schizophrenia.

19 Apr 2021

Study: Gut microbiome can predict changes in Type 2 diabetes related glucose regulation

A study carried out by researchers from the Institute of Genomics, University of Tartu revealed that human gut microbiome can be used to predict changes in Type 2 diabetes related glucose regulation up to four years ahead.

1 Mar 2021

Metabolic Disease News and Research

Researchers identify a single protein that balances sugar and fat metabolism in the liver

Engineered 3D scaffolds of human brown adipose tissue as a new therapeutic strategy for obesity and diabetes

High fat diet exacerbates Alzheimer's disease in mouse model

Existing drug reduces obesity and fatty liver in mice without changes in food intake or daily activity

Study sheds light on the beneficial effects of peanut consumption in young and healthy people

Managing metabolic disease through time-restricted eating

Standing is associated with better insulin sensitivity and metabolic health

Age and sex affect the outcomes of time-restricted eating

Women incur significant out-of-pocket expenses for managing diabetes, finds study

Study finds novel approach to attenuate mitochondrial dysfunction that drives diet-induced obesity

Surplus sugar may cause our cellular powerplants to become less efficient, finds study

Simple method to assess the risk of vascular inflammation for diabetes patients

Detailed performance evaluation of the uEXPLORER total-body PET/CT scanner

Western diet increases COVID-19 severity in a hamster model

Change in diet and circadian clock can impact healthy fat tissue, finds study

New approach to gene therapy uses common pain reliever to fight against genetic diseases

Virginia Tech researcher receives $2.2 million to advance study on small 'fat burning' molecules

Study confirms the importance of low-protein, high-carbohydrate diet

Simple dietary supplement ameliorates schizophrenic traits in mice

Study: Gut microbiome can predict changes in Type 2 diabetes related glucose regulation

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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