Metabolic Disorders News and Research

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Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Researchers described tree-based scan statistics for pediatric long COVID-19.

16 Dec 2022

Type 2 diabetes patients older than 45 have increased MS risk after anti-hyperglycemic exposure

A new University of Arizona Health Sciences study found that people older than 45 whose Type 2 diabetes was treated with anti-hyperglycemic medications had an increased risk of multiple sclerosis, particularly among women, while anti-hyperglycemic exposure in people younger than 45 reduced that risk.

20 Nov 2022

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

A small group of brain cells linked in a circuit is responsible for setting off whole-brain seizures in a rare form of epilepsy affected by blood sugar levels, a study led by UT Southwestern researchers suggests. The finding, published in Science Translational Medicine, could lead to new treatments for other metabolic disorders in the brain, the authors said.

17 Nov 2022

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Scientists have used a proteomics approach to identify a three-protein signature in the blood that can improve detection of isolated impaired glucose tolerance, a form of prediabetes.

10 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

In this interview, we speak to Victor Wong, Chief Scientific Officer at Core Life Analytics, about their StratoMineRTM product and how it helps researchers to rapidly process their data.

From Core Life Analytics 3 Nov 2022

Researchers develop point-of-care device to facilitate monitoring of hereditary and hepatic metabolic disorders

Ammonium is a biomarker used to diagnose a series of rare hereditary metabolic disorders, such as the primary disorders of the urea cycle and different organic acidemias, as well as other metabolic and environmental conditions affecting the liver's function, which can cause a secondary dysfunction of the urea cycle.

3 Nov 2022

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Two of the world's leading authorities on bariatric and metabolic surgery have issued new evidence-based clinical guidelines that among a slew of recommendations expand patient eligibility for weight-loss surgery and endorse metabolic surgery for patients with type 2 diabetes beginning at a body mass index (BMI) of 30, a measure of body fat based on a person's height and weight and one of several important screening criteria for surgery.

21 Oct 2022

Singapore researchers identify protein that transports degraded membrane lipids out of lysosomes

Researchers at Duke-NUS Medical School and colleagues in Singapore have identified a protein that transports degraded membrane lipids out of lysosomes, cellular organelles that are the breakdown factories of cells.

27 Sep 2022

Clinical practice recommendations provide evidence-based clinical guidelines on the management of erectile dysfunction in Australia

New clinical guidelines from the USANZ and the AChSHM for the RACP could help manage erectile dysfunction better "amid saturation advertising of online men's health platforms."

20 Sep 2022

Study establishes a direct link between disruption of circadian clocks and lipid changes in diabetics

A team from Geneva, Switzerland, shows that the disruption of lipid temporal profiles in type 2 diabetes stiffens the membrane of pancreatic endocrine cells, which could alter their function.

19 Sep 2022

Nutritional approaches targeting gut microbiome could improve brain disorders

A new review published in the Clinical Nutrition and Metabolic Care journal focused on studies that utilized the dietary gut microbiota–target interventions to improve mental health conditions. It also discussed some suggestions for developing more robust and informative interventions for diet–microbiome studies.

15 Sep 2022

Neisseria species are linked to worsening bronchiectasis in patients, study shows

A team of international scientists led by the Nanyang Technological University, Singapore (NTU Singapore) has discovered that Neisseria - a genus of bacteria that lives in the human body - is not as harmless as previously thought, and can cause infections in patients with bronchiectasis, asthma, and chronic obstructive pulmonary disease (COPD).

14 Sep 2022

Metabolic Disorders News and Research

Data mining approaches for the detection of signals associated with pediatric post-acute sequelae of COVID-19

Type 2 diabetes patients older than 45 have increased MS risk after anti-hyperglycemic exposure

Inhibitory neuron dysfunction emerges as a modulable mechanism of hyperexcitability

Proteomics approach helps identify protein signatures that can improve detection of prediabetes

Environmental toxicants contribute to obesity and metabolic disease

Circadian disruption induces weight gain through changes in gut microbiota

Accelerating Scientific Discoveries through Advanced Data Analysis Platforms

Researchers develop point-of-care device to facilitate monitoring of hereditary and hepatic metabolic disorders

New evidence-based clinical guidelines expand patient eligibility for metabolic and bariatric surgery

Singapore researchers identify protein that transports degraded membrane lipids out of lysosomes

Clinical practice recommendations provide evidence-based clinical guidelines on the management of erectile dysfunction in Australia

Study establishes a direct link between disruption of circadian clocks and lipid changes in diabetics

Nutritional approaches targeting gut microbiome could improve brain disorders

Neisseria species are linked to worsening bronchiectasis in patients, study shows

Scientists identify two distinct subtypes of obesity

Extreme heat events may increase risk of hypo- and hyperglycemia–related emergencies

Study reveals two distinct types of obesity with physiological and molecular differences

Study reveals gut-brain circuits drive cravings for fatty foods

Recent literature reports on the role of the gut microbiome on human health and its effect on diseases

Young people likely to have increased cholesterol, high BMI, and reduced physical stamina post Covid

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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