Metabolic Disorders News and Research

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COVID-19 pandemic provides a wake-up call to control air pollution

A new commentary published online in the Annals of the American Thoracic Society provides an exhaustive examination of published research that discusses whether air pollution may be linked to worse COVID-19 outcomes.

7 Apr 2021

Exercise during pregnancy can disrupt the vicious cycle of parents-to-child transmission of diseases

Exercise during pregnancy may let mothers significantly reduce their children's chances of developing diabetes and other metabolic diseases later in life, new research suggests.

15 Mar 2021

Study reveals novel approach to reduce the risk of thrombosis by using IgM antibodies

Thrombotic occlusion of blood vessels, which leads to myocardial infarctions, strokes and venous thromboembolisms, is the major cause of death in the western hemisphere.

9 Mar 2021

SARS-CoV-2 escapes host immune responses by modulating dendritic cell maturation

A team of scientists from Italy and the USA has recently explored the maturation pattern of conventional dendritic cells (cDCs) during SARS-CoV-2 infection.

5 Mar 2021

SARS-CoV-2 can evade immune response by T-killer cells through mutations

The body's immune response plays a crucial role in the course of a SARS-CoV-2 infection. In addition to antibodies, the so-called T-killer cells, are also responsible for detecting viruses in the body and eliminating them.

5 Mar 2021

Newly identified biomarker could predict response to immune checkpoint inhibitors

A team of Roswell Park Comprehensive Cancer Center researchers has identified a new biomarker that could predict response to immune checkpoint inhibitors (ICI) shortly after patients with non-small cell lung cancer (NSCLC) initiate therapy.

3 Mar 2021

Combination of therapies may benefit patients with mitochondrial respiratory chain disorders

Researchers from the Mitochondrial Medicine Frontier Program at Children's Hospital of Philadelphia (CHOP) have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

Study demonstrates the novel agonistic effect of curcumin on lipid transcription

Curcumin is a polyphenol compound produced by plants of the Curcuma longa species and has been reported to have many physiological activities, which include anti-oxidation, anti-inflammatory, anti-cancer, and anti-amyloid properties.

27 Feb 2021

Canadian pilot study uses gene therapy to successfully treat patients with Fabry disease

Results of a world-first Canadian pilot study on patients treated with gene therapy for Fabry disease show that the treatment is working and safe.

25 Feb 2021

3D microscopy sheds light on the body’s immune response to obesity

Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood.

18 Feb 2021

Exercise during pregnancy may help mitigate negative effects of parental obesity in children

New research in mice suggests that exercising during pregnancy may help prevent children- especially boys- from developing health problems related to their parents' obesity. The study is published ahead of print in the Journal of Applied Physiology.

11 Feb 2021

Study: Neuron structures are dissimilar between the brain areas in every individual

It was reported that the volume of the brain areas such as the superior temporal gyrus and anterior cingulate cortex reduces in schizophrenia but a precise change of three-dimensional structure of neuron has remained unclear.

11 Feb 2021

GLS1 inhibitor selectively eliminates senescent cells, ameliorates age-associated disorders

Senescent cells accumulate in organs during aging, promote tissue dysfunction, and cause numerous aging-related diseases like cancer. The cells arise through a process called "cellular senescence," a permanent cell cycle arrest resulting from multiple stresses.

5 Feb 2021

Differences in immune response to SARS-CoV-2 determine disease severity, study finds

Researchers investigate host responses to SARS-CoV-2, respiratory syncytial virus (RSV), and influenza virus (IV) in the nasal mucosa in children and adults.

2 Feb 2021

New data shows that mINDY gene is involved in blood pressure regulation

Authors from the German Center for Diabetes Research (DZD) presented data showing that the longevity gene mammalian Indy (mINDY) is involved in blood pressure regulation in the Journal of Clinical Investigation (JCI) insight.

27 Jan 2021

Researchers discover direct link between placental function and future metabolic disorders

Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease.

22 Jan 2021

New model explains controversies over saturated fats and heart disease risk

In science, sometimes a new perspective can turn our interpretation of the data upside-down, and necessitate a paradigm shift.

22 Jan 2021

New technology helps study muscle biology more clearly

Exercising regularly is one of the best defenses against metabolic diseases, such as obesity and diabetes - but why? It's a question that scientists are still struggling to answer. While exercising changes the molecular behavior of muscles, it's not well understood how these molecular changes improve metabolic health.

13 Jan 2021

New type of flour improved the glycemic response of people eating white bread

Researchers from the Quadram Institute and King's College London have shown that replacing wheat flour with a new ingredient derived from chickpeas improved the glycemic response of people eating white bread.

11 Jan 2021

New UCLA-developed device transfers mitochondria into 100,000 or more recipient cells

Scientists from the UCLA Jonsson Comprehensive Cancer Center have developed a simple, high-throughput method for transferring isolated mitochondria and their associated mitochondrial DNA into mammalian cells.

29 Dec 2020