Metabolite News and Research

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Metabolites are the intermediates and products of metabolism. The term ''metabolite'' is usually restricted to small molecules.

Sphere Medical introduces new functionality to Proxima platform for efficient critical care patient monitoring

Sphere Medical, an innovative company in critical care monitoring and diagnostics equipment, announces the introduction of new functionality to its Proxima™ bedside blood gas, electrolyte and metabolite analyser.

22 Mar 2017

Bruker Nano Surfaces to hold webinar on label-free FLIM-based metabolite imaging

Bruker Nano Surfaces will hold a webinar on ‘In Vivo Visualization of Stromal Macrophages via Label-free FLIM-based Metabolite Imaging’ on March 29, 2017 at 8am PST / 11am EST / 3pm GMT.

From Bruker Nano Surfaces and Metrology 20 Mar 2017

Fat cells take over production of uridine from liver during fasting

How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks.

17 Mar 2017

First physiological test opens door to early diagnosis of autism

An algorithm based on levels of metabolites found in a blood sample can accurately predict whether a child is on the Autism spectrum of disorder (ASD), based upon a recent study.

16 Mar 2017

Low levels of allopregnanolone hormone may predict risk of postpartum depression

In a small-scale study of women with previously diagnosed mood disorders, Johns Hopkins researchers report that lower levels of the hormone allopregnanolone in the second trimester of pregnancy were associated with an increased chance of developing postpartum depression in women already known to be at risk for the disorder.

14 Mar 2017

UAlberta research could open door to new therapies for diabetes patients

Jason Dyck has long believed in the beneficial properties of resveratrol--a powerful antioxidant produced by some plants to protect against environmental stresses.

9 Mar 2017

UVA researchers use probiotic bacteria in yogurt to reverse depression symptoms

Researchers at the University of Virginia School of Medicine have reversed depression symptoms in mice by feeding them Lactobacillus, a probiotic bacteria found in live-cultures yogurt.

9 Mar 2017

Research provides insights on how pathogens escape process of autophagy

Our immune system has various ways to deal with threats from the outside like pathogens. One of the defence mechanisms is a process called autophagy.

3 Mar 2017

NR could potentially prevent chemotherapy-induced peripheral neuropathy in cancer patients

A new study in rats suggests that nicotinamide riboside (NR), a form of vitamin B3, may be useful for treating or preventing nerve pain (neuropathy) caused by chemotherapy drugs.

24 Feb 2017

World's largest GWAS on proteomics uncovers molecular mechanisms of complex diseases

The Helmholtz Zentrum München has published results of the largest genome-wide association study on proteomics to date.

16 Feb 2017

Study provides new insight into causes of rare metabolic disorder

Just before Rare Disease Day 2017, a study from the Monell Center and collaborating institutions provides new insight into the causes of trimethylaminura, a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish.

14 Feb 2017

Scientists discover reason behind mosquitoes’ attraction towards people with malaria

Malaria mosquitoes prefer to feed -- and feed more -- on blood from people infected with malaria. Researchers from Stockholm University, the Swedish University of Agricultural Sciences and KTH Royal Institute of Technology have discovered why.

9 Feb 2017

Adjusting KYNA levels can have significant effects on schizophrenia-like behavior, mice study finds

A new study by University of Maryland School of Medicine researchers has found that in mice, adjusting levels of a compound called kynurenic acid can have significant effects on schizophrenia-like behavior. The study appeared in the latest issue of the journal Biological Psychiatry.

7 Feb 2017

Researchers identify new mechanism that protects from bacterial infections

An international team led by the University if Barcelona has identified a new antibacterial mechanism that protects macrophages - defense cells in the immune system- from the infection of the bacteria Salmonella enterica serovar Typhimurium, a pathogen associated with several gastrointestinal diseases.

2 Feb 2017

Researcher develops new method to accurately identify elusive molecules

Among the most important molecules in the living world are sugars or carbohydrates, which play a vital role in life processes. Sugars provide the main source of fuel for the body, protect muscles from damage and contribute to the immune response.

21 Dec 2016

Replacing missing gut bacteria could help treat children with rare autoimmune disease

Defects in the body's regulatory T cells (T reg cells) cause inflammation and autoimmune disease by altering the type of bacteria living in the gut, researchers from The University of Texas Health Science Center at Houston have discovered.

19 Dec 2016

Research unlocks potential new therapies for inflammatory diseases

Macrophages are frontline cells in our immune system. They detect microbial invaders and also tissue injury and then mount an appropriate response needed to clear the infection and repair the damaged tissue.

5 Dec 2016

Researchers identify metabolite that promotes epithelial-mesenchymal transition of colorectal cancer cells

Osaka University researchers revealed that the metabolite D-2-hydroxyglurate (D-2HG) promotes epithelial-mesenchymal transition of colorectal cancer cells, leading them to develop features of lower adherence to neighboring cells, increased invasiveness, and greater likelihood of metastatic spread.

1 Dec 2016

Researchers develop virtual liver model to better understand metabolism of non-prescription painkiller

Researchers at Indiana University's Biocomplexity Institute have developed a virtual model of the human liver to better understand how the organ metabolizes acetaminophen, a common non-prescription painkiller and fever-reducer used in over-the-counter drugs such as Tylenol.

29 Nov 2016

Metabolomics research at the Phenome Centre Birmingham

An interview with Professor Mark Viant, University of Birmingham, UK, Executive Director of Phenome Centre Birmingham and Director of the NERC Biomolecular Analysis Facility.

From Bruker BioSpin - NMR, EPR and Imaging 28 Nov 2016