Methionine News and Research

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Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

A new study describes mutations found in the SARS-CoV-2 BA.1 variant in Hong Kong and New Zealand.

20 Mar 2022

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

In a recent study posted to the medRxiv* preprint server, researchers evaluated if folic acid or methotrexate use impacts the risk of coronavirus disease 2019 (COVID-19) diagnosis or associated mortality in the United Kingdom (UK).

15 Feb 2022

RNA capping mechanism of SARS-CoV-2 unveiled

In a recent study posted to the bioRxiv* preprint server, researchers elucidated the mechanism of ribonucleic acid (RNA) capping in severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2).

14 Feb 2022

Discovery may lead to new treatment approach for people with alcohol-associated liver disease

Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease.

14 Feb 2022

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

Eating more meat, having less of certain bacteria in the gut, and more of certain immune cells in the blood, all link with multiple sclerosis, reports a team of researchers led by UConn Health and Washington University School of Medicine.

27 Jan 2022

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Researchers examine the role of human sirtuin 5 (SIRT5) in SARS-CoV-2 infection.

10 Jan 2022

Exploring the importance of selenium in COVID-19 patients

In a new study, researchers reviewed research on the role that selenium could play in protecting individuals against coronavirus disease 2019.

29 Dec 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

SARS-CoV-2 infection regulates protein arginylation

A new study explores the role of arginylation during SARS-CoV-2 infection.

9 Nov 2021

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

Worms don't wiggle when they have Alzheimer's disease. Yet something helped worms with the disease hold onto their wiggle in Professor Jessica Tanis's lab at the University of Delaware.

29 Sep 2021

Novel natural compounds may help treat COVID-19, study suggests

A new study in the journal Chemistry Europe reports two natural compounds identified by virtual screening and computational modeling as having great promise for the development of drugs against SARS-CoV-2.

24 May 2021

Research opens up the possibility of dietary therapy for cancer

A research group at the RIKEN Center for Biosystems Dynamics Research (BDR) has discovered molecular events that determine whether cancer cells live or die. With this knowledge, they found that reduced consumption of a specific protein building block prevents the growth of cells that become cancerous.

27 Apr 2021

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

A chemical modification of RNA that can be influenced by diet appears to play a key role in polycystic kidney disease, an inherited disorder that is the fourth leading cause of kidney failure in the U.S., UT Southwestern researchers report in a new study.

13 Apr 2021

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

Beyond vaccination, the broad-spectrum antiviral medication remdesivir has robust clinical evidence and is known as the best antiviral treatment to reduce severe COVID-19 infection in hospitalized patients. Research led by John F.X. Diffley of the Chromosome Replication Laboratory suggests a potential therapeutic target for treatment development is the viral RNA cap methyltransferases, essential for viral protein translation and immune evasion.

13 Apr 2021

Screening for SARS-CoV-2 non-structural protein 14 inhibitors

In a paper recently uploaded to the preprint server bioRxiv* by Diffley et al. (April 8th, 2021), inhibitors of one essential SARS-CoV-2 non-structural protein are explored, with four compounds, in particular, identified as potential antiviral leads that exhibit synergistic effects with antiviral drug remdesivir.

12 Apr 2021

Discovery of cryptic pocket in SARS-CoV-2 may lead to pan-coronavirus therapies

A new research paper published in the Biophysical Journal describes a novel binding pocket used by a viral non-structural protein (nsp) to form an activated complex with its partner nsp. In so doing, it may have revealed a common target that may be useful in the development of a broad-spectrum antiviral drug against all coronaviruses.

1 Apr 2021

Methionine News and Research

Omicron BA.1.1 and BA.2 subvariants with new mutations in New Zealand and Hong Kong

Study suggests folic acid supplementation linked to increased risk for COVID-19 diagnosis

RNA capping mechanism of SARS-CoV-2 unveiled

Discovery may lead to new treatment approach for people with alcohol-associated liver disease

Research teases out connection between diet, immune response, gut bacteria and multiple sclerosis

SARS-CoV-2 levels decrease when human SIRT5 is deleted or inhibited

Exploring the importance of selenium in COVID-19 patients

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

SARS-CoV-2 infection regulates protein arginylation

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

Novel natural compounds may help treat COVID-19, study suggests

Research opens up the possibility of dietary therapy for cancer

Chemical modification of RNA appears to play a critical role in inherited kidney disorder

Inhibition of nsp14 methyltransferase as a potential antiviral target for SARS-CoV-2

Screening for SARS-CoV-2 non-structural protein 14 inhibitors

Discovery of cryptic pocket in SARS-CoV-2 may lead to pan-coronavirus therapies

Mice study provides insight into the beneficial effects of selenium supplementation

The role of RNA capping of SARS-CoV-2 in immunity evasion

A genetic variant of TMPRSS2 may confer protection against severe COVID-19

Study reveals mechanisms behind sensitivity of multiple myeloma cells to EZH2 inhibition

Achieving and maintaining ISO 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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