A Microbicide is any substance or process that kills germs (bacteria, viruses, and other microorganisms that can cause infection and disease). Also called germicide.
In a symposium session on Monday at the XIX International AIDS Conference in Washington, D.C., politicians and public health experts joined Bill & Melinda Gates Foundation Co-Chair Bill Gates for a discussion about improving effectiveness and efficiency in the HIV/AIDS response, the Washington Post reports.
A large clinical trial testing the long-term safety and effectiveness of a new approach for preventing HIV in women - a vaginal ring used once a month - is now underway in Africa, researchers announced today at the XIX International AIDS Conference (AIDS 2012).
A new Lancet Series published to coincide with the AIDS2012 meeting highlights a population where the HIV epidemic is growing in countries of all incomes: men who have sex with men (MSM). The first paper in the Series charts the epidemiology of HIV among MSM, and is by Professor Chris Beyrer, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA, and colleagues.
GlobalPost's "Global Pulse" blog features an interview with Zeda Rosenberg, CEO of the International Partnership for Microbicides (IPM), in which she discusses a study of a vaginal ring containing the antiretroviral (ARV) dapivirine.
While immediate postexposure treatment for suspected HIV is critical, pre-exposure preventive treatment is a newer method that may be effective for people in high-risk groups, states a review of evidence published in CMAJ (Canadian Medical Association Journal).
The House Appropriations Committee is scheduled to mark up the FY 2013 State and Foreign Operations appropriations bill on Thursday, The Hill's "Global Affairs" blog reports.
A change in the formulation of tenofovir gel, an anti-HIV gel developed for vaginal use, may make it safer to use in the rectum, suggests a study published online this week in the Journal of Antimicrobial Chemotherapy. In laboratory tests of rectal tissue, researchers from the Microbicide Trials Network (MTN) found that the reformulated gel was less harmful to the lining of the rectum than the original vaginal formulation, and just as effective in protecting cells against HIV.
In public comments submitted this week, a group of 14 leading HIV/AIDS and health organizations stated their support for Food and Drug Administration (FDA) approval of emtricitabine/ tenofovir disoproxil fumarate (TDF/FTC or Truvada) as pre-exposure prophylaxis (PrEP) to prevent HIV infection in adult men and women.
The conclusion of the 2012 International Microbicides Conference, a gathering of researchers, advocates and funders in the HIV prevention field, wrapped up three days of discussion focused on access to prevention technologies, adherence in clinical trials, innovative financing, dual prevention technologies and new methods of preventing rectal transmission of HIV.
This year's International Microbicides Conference, held this week in Sydney, "will be the last of its kind" because "from 2014 onwards, it is planned, a single biennial conference on all aspects of HIV prevention will be held," according to an aidsmap news story.
"Although the research for new HIV prevention technologies has indeed made some progress, ... a formidable way lies ahead to find enough money to finish the research and to make 'from discovery to delivery' a reality for those in need of protecting themselves from HIV," CNS/Scoop.co.nz reports.
Are women willing to use a vaginal gel to protect themselves against HIV infection? Researchers at The Miriam Hospital say that is the million dollar question when it comes to developing products known as microbicides that can prevent the sexual transmission of HIV.
"Three decades after the full onset of the global HIV tragedy, science appears to finally be developing preventative measures, including microbicides that would thwart infections in the first place, according to individuals at" the biennial International Microbicides Conference in Sydney, the Asia Sentinel writes.
"More than three years after reporting the primary results of HPTN 035, one of the last trials of the so-called first generation microbicides, researchers from the National Institutes of Health-funded Microbicide Trials Network (MTN) reported two new sets of findings gleaned" from the study data at the International Microbicides Conference in Sydney on Tuesday, an MTN press release states.
An HIV prevention trial that pre-dates the shift to antiretroviral (ARV)-based approaches is nonetheless helping to answer some of the most relevant and topical questions the field is facing today.
Researchers, activists and funders are meeting this week in Sydney to discuss the state of HIV prevention research. The biennial International Microbicides Conference, which was opened on Sunday evening by the Honorable Tanya Plibersek MP, Australian Minster of Health, is taking place amid renewed optimism about development and delivery of new HIV prevention options with the potential for ending the AIDS epidemic, including anti-retroviral based microbicides and pre-exposure prophylaxis.
The biennial International Microbicides Conference is the premier gathering for those working on new approaches to HIV prevention and this year's conference in Sydney, Australia will place a strong emphasis on the role of community in both research and implementation of scientific findings. The conference will take place from April 15-18 at the Sydney Exhibition and Conference Centre located on the Darling Harbour waterfront.
AllAfrica.com examines efforts by African researchers to develop a female-controlled HIV prevention method, writing, "Scientists searching for a gel or vaccine that can prevent HIV infection ride a rollercoaster of hope and disappointment." The article profiles efforts by researchers from the Centre for the AIDS Program of Research in South Africa (Caprisa) to find a microbicide gel to protect women from HIV infection.
Starpharma today announced that it has received final written agreement from the FDA on the design of its Phase 3 clinical studies of VivaGel® for the treatment of bacterial vaginosis (BV) under the FDA’s Special Protocol Assessment (SPA) scheme.
Researchers involved with a multi-armed clinical trial designed to evaluate different antiretroviral (ARV) interventions for HIV prevention on Friday announced the arm testing a vaginal gel had been stopped because it was not working, the New York Times reports.