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Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The authors of the current study looked at the potential for an increased risk of parkinsonism following a bout of SARS-CoV-2 infection through accepted post-viral mechanisms.

20 May 2022

The enigma of post-acute infection syndromes

In a recent review published in the journal Nature Medicine, researchers summarized known literature findings of the unexplained post-acute infection syndromes (PAISs).

20 May 2022

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

SARS-CoV-2 infection could increase the risk of brain degeneration seen in Parkinson's disease

Brain fog, headaches, insomnia are some of the neurological symptoms doctors have observed in COVID-19 patients.

18 May 2022

COVID-19-induced non-cell-autonomous anosmia

Researchers reported that SARS-CoV-2-induced anosmia was based on non-cell-independent processes.

11 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

An international research group led by Professor Toru Takumi (Senior Visiting Scientist, RIKEN Center for Biosystems Dynamics Research) and Researcher Chia-wen Lin at Kobe University Graduate School of Medicine has shown that idiopathic autism is caused by epigenetic abnormalities in hematopoietic cells during fetal development, which results in immune dysregulation in the brain and gut.

2 May 2022

Researchers discover more needles in the haystack in the quest to unravel Alzheimer’s disease

21 million. That's the number of genetic variations in the human genome that researchers are sifting to identify patterns predisposing people to Alzheimer's disease.

20 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons -; more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Alzheimer's disease (AD), the most common type of dementia, progressively impairs memory, concentration and the ability to learn new things and accomplish everyday activities.

19 Apr 2022

Immune cell responses to bacteria affect intrinsic excitability of neuronal subtypes differently

A new study reports that immune cell responses to bacteria affect the intrinsic excitability of rat neuronal subtypes differently.

19 Apr 2022

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Inhibiting an important signaling pathway in brain-resident immune cells may calm brain inflammation and thereby slow the disease process in Alzheimer's and some other neurodegenerative diseases, suggests a study by Weill Cornell Medicine investigators.

14 Apr 2022

Innovative imaging technique may pave the way for better understanding and treatment of spinal cord injury

A research team led by scientists from the Hong Kong University of Science and Technology has developed an innovative technology for in vivo imaging of the important biological processes involved in the injury and repair of spinal cords, paving the way for a better understanding of the pathology and potential treatment of spinal cord injury (SCI).

12 Apr 2022

Microglia News and Research

Study explores if prior infection with SARS-CoV-2 increased sensitivity to a mitochondrial toxin known to induce parkinsonism

The enigma of post-acute infection syndromes

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

SARS-CoV-2 infection could increase the risk of brain degeneration seen in Parkinson's disease

COVID-19-induced non-cell-autonomous anosmia

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

Epigenetic abnormalities in hematopoietic cells during fetal development cause idiopathic autism

Researchers discover more needles in the haystack in the quest to unravel Alzheimer’s disease

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Type I interferon found to be major driver of memory, cognitive loss in Alzheimer's disease mouse model

Immune cell responses to bacteria affect intrinsic excitability of neuronal subtypes differently

Inhibiting key signaling pathway in immune cells may slow down Alzheimer's disease

Innovative imaging technique may pave the way for better understanding and treatment of spinal cord injury

Researchers discover over 40 new genetic markers for Alzheimer’s disease

Scientists describe use of PCR in detecting SARS-CoV-2 in paraffine-embedded tissues

Niacin limits Alzheimer's disease progression in animal model

Neutrophils found to initiate COVID-19-associated olfactory epithelial damage in hamsters

Huddersfield researchers demonstrate how coronavirus activates the brain's immune response

Alzheimer’s disease protein helps skin cancer cells thrive when they metastasize to the brain

Pain neuron-derived peptide protects mice from endotoxic death by enhancing brain ATP production

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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