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New laboratory study shows certain protein particles multiply, spread from one cell to another

In diseases like Alzheimer's and Parkinson's endogenous proteins accumulate in the brain, eventually leading to the death of nerve cells. These deposits, which consist of abnormally formed proteins, are supposed to migrate between interconnected areas of the brain, thereby contributing to the development of the illness.

28 Mar 2013

Scientists discover new mechanism that regulates replication of insulin-producing beta cells in pancreas

Bringing scientists a step closer to new treatments for diabetes, researchers at the University of Pittsburgh School of Medicine and The Mount Sinai Medical Center have discovered a novel mechanism that regulates the replication of insulin-producing beta cells in the pancreas.

27 Mar 2013

Study: Gene therapy can boost heart muscle function

In an animal study, researchers at the University of Washington show that it is possible to use gene therapy to boost heart muscle function. The finding suggests that it might be possible to use this approach to treat patients whose hearts have been weakened by heart attacks and other heart conditions.

27 Mar 2013

Left and right sides of heart develop differently, research shows

Viewed from the outside, our body looks completely symmetrical. However, most internal organs - including the heart - are formed asymmetrically.

27 Mar 2013

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

Early diagnosis is critical in treating Lyme disease. However, nearly one quarter of Lyme disease patients are initially misdiagnosed because currently available serological tests have poor sensitivity and specificity during the early stages of infection.

27 Mar 2013

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Researchers at Moffitt Cancer Center and colleagues at the University of South Florida have developed a small molecule that inhibits STAT3, a protein that causes cancer.

26 Mar 2013

Eating behavior could act as defense mechanism against infections and autoimmune disorders

Neurons that control hunger in the central nervous system also regulate immune cell functions, implicating eating behavior as a defense against infections and autoimmune disease development, Yale School of Medicine researchers have found in a new study published in the Proceedings of the National Academy of Sciences (PNAS).

26 Mar 2013

A new strategy to prevent herpes virus infections

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered a novel strategy for preventing infections due to the highly common herpes simplex viruses, the microbes responsible for causing genital herpes (herpes simplex virus 2) and cold sores (herpes simplex virus 1).

26 Mar 2013

Two studies shed light on molecular biology of three blood disorders

Two studies led by investigators at Weill Cornell Medical College shed light on the molecular biology of three blood disorders, leading to novel strategies to treat these diseases.

26 Mar 2013

BioCryst starts BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

BioCryst Pharmaceuticals, Inc. announced the initiation of a Phase 1 clinical trial to evaluate the safety, pharmacokinetics and pharmacodynamics of orally-administered BCX4161 in healthy volunteers.

25 Mar 2013

Newly discovered molecule could form the basis of anti-malaria drugs

An international study, involving researchers from Griffith University's Eskitis Institute, has discovered a molecule which could form the basis of powerful new anti-malaria drugs.

25 Mar 2013

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

The over-the-counter anti-inflammatory drug naproxen may also exhibit antiviral activity against influenza A virus, according to a team of French scientists. The finding, the result of a structure-based investigation, is published online ahead of print in the journal Antimicrobial Agents and Chemotherapy.

25 Mar 2013

Protein with key job in muscle function moonlights in nucleus to help regulate genes

A key building block of life, actin is one of the most abundant and highly conserved proteins in eukaryotic cells.

25 Mar 2013

Study reveals role of SNX27 protein in brain function

What is it about the extra chromosome inherited in Down syndrome-chromosome 21-that alters brain and body development? Researchers at Sanford-Burnham Medical Research Institute have new evidence that points to a protein called sorting nexin 27, or SNX27.

25 Mar 2013

LMU researchers identify microRNA that offers promising target for new therapies

Atherosclerosis, an inflammatory reaction, is at the root of the most common forms of cardiovascular disease. Researchers at Ludwig-Maximilians-Universitaet in Munich have now identified a microRNA that plays a prominent role in the process, and offers a promising target for new therapies.

25 Mar 2013

Researchers study how nerve cells repair themselves after injury

One molecule makes nerve cells grow longer. Another one makes them grow branches. These new experimental manipulations have taken researchers a step closer to understanding how nerve cells are repaired at their farthest reaches after injury.

25 Mar 2013

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Collaborating scientists from Nationwide Children's Hospital, Baylor Institute for Immunology Research, and Mount Sinai School of Medicine have identified an important mechanism for stimulating protective immune responses following seasonal influenza vaccinations.

25 Mar 2013

Epizyme receives patent for drug candidate for genetically defined type of non-Hodgkin lymphomas

Epizyme, Inc., a clinical stage biopharmaceutical company creating innovative personalized therapeutics for patients with genetically defined cancers, announced today that it has received a Notice of Issuance from the U.S. Patent and Trademark Office for its patent application entitled "ARYL-OR HETEROARYL-SUBSTITUTED BENZENE COMPOUNDS", U.S. Patent No.: 8,410,088.

24 Mar 2013

MU researchers redefine key regulatory process in defective protein responsible for cystic fibrosis

A little more than a year after the FDA approved Kalydeco (Vx-770), the first drug of its kind to treat the underlying cause of cystic fibrosis, University of Missouri researchers believe they have found exactly how this drug works and how to improve its effectiveness in the future.

22 Mar 2013

Findings provide structural basis for development of drugs to fight enterovirus 71 infection

New research findings may help scientists design drugs to treat a virus infection that causes potentially fatal brain swelling and paralysis in children.

22 Mar 2013

Molecule News and Research

New laboratory study shows certain protein particles multiply, spread from one cell to another

Scientists discover new mechanism that regulates replication of insulin-producing beta cells in pancreas

Study: Gene therapy can boost heart muscle function

Left and right sides of heart develop differently, research shows

Penn researchers develop nanotechnology-inspired technique for diagnosing Lyme disease

STAT3 protein's ability to cause malignancy is suppressed when neutralized by S31-1757

Eating behavior could act as defense mechanism against infections and autoimmune disorders

A new strategy to prevent herpes virus infections

Two studies shed light on molecular biology of three blood disorders

BioCryst starts BCX4161 Phase 1 clinical trial for treatment of hereditary angioedema

Newly discovered molecule could form the basis of anti-malaria drugs

Anti-inflammatory drug naproxen may exhibit antiviral activity against influenza A virus

Protein with key job in muscle function moonlights in nucleus to help regulate genes

Study reveals role of SNX27 protein in brain function

LMU researchers identify microRNA that offers promising target for new therapies

Researchers study how nerve cells repair themselves after injury

Study shows certain T cells are stimulated to provide protective antibody responses with flu vaccines

Epizyme receives patent for drug candidate for genetically defined type of non-Hodgkin lymphomas

MU researchers redefine key regulatory process in defective protein responsible for cystic fibrosis

Findings provide structural basis for development of drugs to fight enterovirus 71 infection

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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