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Nicotine rush hinges on sugar in neurons

As with other questions involving good sensations, the answer appears to be sugar.

23 Jul 2007

Koronis Pharmaceuticals issued U.S. patent for KP-1461 therapeutic in development for treatment of HIV

Koronis Pharmaceuticals, Inc. has announced the issuance of U.S. Patent No. 7,244,732 that discloses the composition of KP-1461 -- the Company's lead antiviral therapeutic currently in a Phase 2 trial for the treatment of human immunodeficiency virus (HIV) infection.

23 Jul 2007

Nanotechnology to test food quality

Researchers have created two tiny instruments capable of detecting a range of contaminants, from molecules to whole bacteria, in food and water, according to an article in the August issue of Microbiology Today.

23 Jul 2007

Protein synthesis without amino acids

Usually, the synthesis of short protein chains (polypeptides) begins with the production of their components, the amino acids.

20 Jul 2007

Lubert Stryer wins National Medal of Science

Neurobiologist Lubert Stryer, MD, of the Stanford University School of Medicine, will receive the nation's highest scientific honor, the National Medal of Science, for his achievements in a wide range of fields that included the development of a DNA chip used in genetics.

19 Jul 2007

Plumber protein uses different tools to turn on genes

St. Jude investigators have discovered how a single molecular "on switch" triggers gene activity that might cause effects ranging from learning and memory capabilities to glucose production in the liver.

18 Jul 2007

Preconditioning protects brain from stroke

Challenging brain tissue with a small noxious stimulus beforehand gives it a resilience that can lessen damage to blood vessels during a stroke, report researchers at Weill Cornell Medical College in New York City.

18 Jul 2007

New method for early disease diagnosis

Purdue University researchers worked with the Indiana University School of Medicine to establish a technique that provides a new approach for detecting a number of genetic disorders found in infants and young children.

18 Jul 2007

Heart patches that stimulate regeneration

When human hearts are injured, as during a heart attack, healthy tissue normally can't regrow.

18 Jul 2007

Grapefruit linked to increased risk for breast cancer

It seems unlikely but researchers in the United States say they have found that eating too much grapefruit could increase the risk of breast cancer.

17 Jul 2007

Insights into side effects of HIV protease inhibitors

UCLA scientists, along with collaborators from Purdue University, have demonstrated that HIV protease inhibitors, crucial drugs for HIV treatment block a cellular enzyme important for generating the structural scaffolding for the cell nucleus.

17 Jul 2007

Biota and MedImmune announce clinical trial for respiratory syncytial virus antiviral drug

Biota Holdings Limited and MedImmune Inc. today announced the start of a Phase Ia clinical trial for their respiratory syncytial virus (RSV) antiviral drug, BTA9881, with the goal of providing a treatment for RSV-infected infants and adults.

17 Jul 2007

Researchers identify new combination therapy that promotes cancer cell death

Researchers at the University of Pennsylvania School of Medicine identified a combination therapy as a way to sensitize resistant human cancer cells to a treatment currently being tested in clinical trials They propose that the therapy may help to selectively eliminate cancer cells while leaving healthy cells intact, providing a cancer treatment with fewer side effects.

17 Jul 2007

New hope for childhood cancer sufferers

Scientists investigating drug therapies for children with Acute Lymphoblastic Leukaemia (ALL) have presented new data demonstrating for the very first time that a small molecule called ABT-737 can increase the effectiveness of standard therapies.

17 Jul 2007

Researchers determine structure of protein from pathogen associated with cystic fibrosis

The structure of a novel protein in the bacterium that is the most persistent pathogen in cystic fibrosis (CF) patients has been solved.

16 Jul 2007

DNA' s double helix shape explained

Researchers at Duke University's Pratt School of Engineering have uncovered a missing link in scientists' understanding of the physical forces that give DNA its famous double helix shape.

13 Jul 2007

Eye lens and nose cells for smelling have same origin

A team of researchers at Umeå University in Sweden have discovered a unique mechanism by which the same signal molecule determines the formation of the both the lens of the eye and the olfactory cells of the nose.

13 Jul 2007

Next generation painkillers

Scientists studying one of nature's simplest organisms have helped to unravel the structure of a key molecule that controls pain in humans.

From The University of Manchester 12 Jul 2007

White blood cells are picky about sugar

Biology textbooks are blunt - neutrophils are mindless killers. These white blood cells patrol the body and guard against infection by bacteria and fungi, identifying and destroying any invaders that cross their path. But new evidence, which may lead to better drugs to fight deadly pathogens, indicates that neutrophils might actually distinguish among their targets.

11 Jul 2007

Catalyst Pharmaceutical Partners starts U.S. phase II trial of CPP-109 in patients with cocaine dependence

Catalyst Pharmaceutical Partners, Inc. a specialty pharmaceutical company that acquires or in-licenses, develops and commercializes prescription drugs for the treatment of drug addiction, today announced that it has initiated its randomized, double-blind, placebo-controlled U.S. Phase II clinical trial of CPP-109 in patients with cocaine dependence.

11 Jul 2007