Monoclonal Antibody News and Research

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Monoclonal antibodies (MAbs) are produced from a single B cell clone and can bind to a single type of antigen binding site. MAbs are homogenous antibodies that cannot form lattices with monomeric proteins as they can bind to only a single epitope on the antigen. Developed in the 1970s, MAbs can be produced against any given substance. Thus they can be used to detect and purify any substance of interest. This has made MAbs a powerful tool of molecular biology, biochemistry, and medicine.
Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Study finds increased risk of mortality in people with cold agglutinin disease in five years after diagnosis

Study finds increased risk of mortality in people with cold agglutinin disease in five years after diagnosis

Innovative drugs and new European treatment guidelines refine, improve MS therapy

Innovative drugs and new European treatment guidelines refine, improve MS therapy

Canakinumab reduces gout rate by more than half in atherosclerosis patients, study shows

Canakinumab reduces gout rate by more than half in atherosclerosis patients, study shows

Regeneron collaborates with Zoetis to research antibody therapies for animals

Regeneron collaborates with Zoetis to research antibody therapies for animals

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

Phase I trial shows safety of investigational drug in treating chronic lymphocytic leukemia

OSU biologist describes 'restoration ecology' approach toward patient health

OSU biologist describes 'restoration ecology' approach toward patient health

Researchers reveal potent new mechanism of action for treatment of IBD

Researchers reveal potent new mechanism of action for treatment of IBD

NIH commences first-in-human trial evaluating experimental treatment for Ebola

NIH commences first-in-human trial evaluating experimental treatment for Ebola

Comparative Analysis of a Complex Monoclonal Antibody

Comparative Analysis of a Complex Monoclonal Antibody

UAB-led clinical trial intends to find innovative treatment for multiple myeloma patients

UAB-led clinical trial intends to find innovative treatment for multiple myeloma patients

Study identifies new biomarker for early lung cancer diagnosis

Study identifies new biomarker for early lung cancer diagnosis

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

Ocular oncologists link immunotherapy with potentially vision-robbing side effect

New treatment option appears promising for patients with glucocorticoid-induced osteoporosis

New treatment option appears promising for patients with glucocorticoid-induced osteoporosis

New drug for migraine in the pipeline

New drug for migraine in the pipeline

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

PCSK9 inhibitor reduces cardiovascular events in ACS patients with high cholesterol

Innovative antibody delivery method could offer effective way to combat Ebola infection

Innovative antibody delivery method could offer effective way to combat Ebola infection

Highly sensitive ELISA method for analysis of CET in plasma samples

Highly sensitive ELISA method for analysis of CET in plasma samples

AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

AbbVie and Voyager Therapeutics collaborate to develop new treatments for tauopathies

Extending dosing intervals makes common multiple sclerosis drug safer to use

Extending dosing intervals makes common multiple sclerosis drug safer to use