Mood Disorder News and Research

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Urban dwellers at greater risk of mental illness: Study

A new study shows that living in a city increases the risk of developing a mental disorder, including depression and schizophrenia, compared to people who live in non-urban areas. The findings of the has implications for around half of the world's population who live in cities.

23 Jun 2011

Adjusting life goals can help family caregivers prevent depressive symptoms: Study

Caring for a family member with a mental illness can be a taxing experience marked by personal sacrifices and psychological problems.

21 May 2011

New study reveals a novel gene linked with major depression

A new study reveals a novel gene associated with major depression. The research, published by Cell Press in the April 28 issue of the journal Neuron, suggests a previously unrecognized mechanism for major depression and may guide future therapeutic strategies for this debilitating mood disorder.

28 Apr 2011

New study provides fascinating insight into genetic basis of bipolar disorder

A new study provides fascinating insight into the genetic basis of bipolar disorder, a highly heritable mood disorder characterized by recurrent episodes of mania and depression.

3 Mar 2011

Neuralstem announces initiation of NSI-189 Phase Ia trial for major depressive disorder

Neuralstem, Inc. announced that the first subject was dosed yesterday in a Phase Ia trial to evaluate the safety of its drug, NSI-189, which is being developed for the treatment of major depressive disorder and other psychiatric indications. NSI-189 is the lead compound in Neuralstem's neurogenerative small molecule drug platform. This phase of the trial is in healthy volunteers and seeks to determine the maximum tolerated single dose.

2 Mar 2011

NIMH awards Case Western Reserve $7.8M renewal grant to study manic symptoms in children

The Department of Psychiatry at Case Western Reserve University School of Medicine has received a $7.8 million renewal grant from the National Institute of Mental Health (NIMH) for the long-term study of manic symptoms in children.

21 Jan 2011

MGH Bipolar CHOICE trial to evaluate effectiveness of new medications compared to lithium

The Massachusetts General Hospital (MGH) Bipolar Clinic and Research Program with the Bipolar Trials Network is launching Bipolar CHOICE, a 10-site nationwide trial evaluating the real-world advantages and disadvantages of quetiapine, a widely prescribed second generation antipsychotic mood stabilizing medication, compared to lithium, the gold standard mood stabilizer, for the treatment of outpatients with bipolar disorder.

21 Jan 2011

UH, Case Western University commence clinical trial for bipolar disorder

The Mood Disorders Program at Case Western Reserve University School of Medicine and University Hospitals Case Medical Center, along with the Bipolar Trials Network, is launching Bipolar CHOICE.

12 Jan 2011

Stigma remains over Major Depressive Disorder

Despite there being 39.1 million people suffering from major depressive disorder (MDD) across the seven major markets, only one third of patients will seek help from a physician, finds latest research from independent analyst Datamonitor.

11 Jan 2011

Intentional foreign body ingestion results in over $2 million hospital costs: Study

A new study from Rhode Island Hospital found that 33 individuals were responsible for 305 cases of medical intervention to remove foreign bodies that were intentionally swallowed, resulting in more than $2 million in estimated hospital costs. The findings appear in the November issue of Clinical Gastroenterology and Hepatology.

1 Nov 2010

Canadians living with depression significantly underestimate others' perceptions about illness

A new national survey reveals a vast gap between how Canadians living with depression view their condition, compared to how it is viewed in reality by the general population, possibly preventing them from seeking the best treatment and care. Most Canadians with depression feel their illness is not perceived by the public as a medical condition or a serious illness (81 per cent) when in fact less than five per cent of the general population actually has that view. In fact, the majority of Canadians (72 per cent) recognize depression as both serious and treatable.

29 Sep 2010

Depression and anxiety disorders common in loved ones of breast cancer patients: Study

Earlier studies have shown that women living with breast cancer are at a risk of depression but new studies have shown that their partners are at a similar risk. The study looked at more than a million men enrolled in a nationwide Danish health registry followed for 13 years.

28 Sep 2010

Depression in children and teens need to be treated early

Depression in children and teenagers can be very debilitating and can have a lifelong impact. Parents who suspect their child, even their youngster, might be depressed should seek help right away rather than simply hope their child will eventually "grow out of it."

14 Sep 2010

23rd ECNP Press conference on impact of circadian rhythms on human brain

All humans are synchronised to the rhythmic light-dark changes that occur on a daily basis. Rhythms in physiological and biochemical processes and behavioural patterns persist in the absence of all external 24-hour signals from the physical environment, with a period that is close to 24 hours

30 Aug 2010

Students with ADHD less likely to finish high school graduation: Study

Teens with attention-deficit/hyperactivity disorder - the most common childhood psychiatric condition in the United States - are less likely to finish high school on time than students with other mental-health disorders that often are considered more serious, a large national study by researchers at the UC Davis School of Medicine has found. The study found that nearly one third of students with ADHD, twice the proportion as students with no psychiatric disorder, either drop out or delay high school graduation.

28 Jul 2010

New hope for patients with drug-resistant depression

New research shows that a unique strain of laboratory mice characterized at Penn State University has behavioral, hormonal, and neurochemical characteristics that are similar to those of human patients with drug-resistant forms of depression.

30 Jun 2010

New book gives hope to women and families who are in difficult stages of anorexia treatment

Women and families struggling with an eating disorder or another addiction should never lose sight of the need to sustain the spirit, according to a new book by Jena Morrow, an author in recovery after more than 20 years with anorexia nervosa. Morrow, a behavioral health specialist at Timberline Knolls Residential Treatment Center, details a battle with anorexia that begins in early childhood in Hollow: An Unpolished Tale, recently released by Moody Publishers.

17 Jun 2010

Patterns consolidate features of older theories, may help diagnosis of psychiatric disorders

In a study appearing in the journal PLoS ONE, Massachusetts General Hospital scientists describe finding mathematical patterns underlying the way individuals unconsciously distribute their preferences regarding approaching or avoiding objects in their environment.

27 May 2010

Mood and anxiety disorders associated with poor health outcomes

Rates of mood and anxiety disorders appear to decline with age but the conditions remain common in older adults, especially women, according to a report in the May issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

4 May 2010

Distinct gender differences underlying risks for abuse of prescription pain drugs: Study

There are distinct gender differences underlying the risks for abuse of prescription pain drugs, according to a Harvard study published in The Journal of Pain, the peer review journal of the American Pain Society, www.ampainsoc.org and www.jpain.org.

28 Apr 2010