Mutation News and Research

RSS

APC enzyme may be effective for treating amyotrophic lateral sclerosis

A chemical cousin of a drug currently used to treat sepsis dramatically slows the progression of amyotrophic lateral sclerosis, better known as ALS or Lou Gehrig's disease, in mice. The results offer a bit of good news in efforts to develop a therapy to stop or slow the progression of a disease that generally kills its victims within just a few years.

26 Oct 2009

2009 Inspiration Gala raises $1.27 million for BC Cancer Foundation

The 2009 Inspiration Gala raised $1.27 million for the BC Cancer Foundation and colorectal cancer research at the BC Cancer Agency last night, as nearly 400 guests dined and donated during the emotion-filled, sold-out event.

24 Oct 2009

Follow healthy lifestyle to overturn genetic predisposition to heart disease

When it comes to heart disease, lifestyle usually trumps genetics, says noted genetic researcher Dr. Robert Hegele, Heart and Stroke Foundation of Canada Lecturer at the Canadian Cardiovascular Congress 2009.

23 Oct 2009

Adjuvanted and non-adjuvanted H1N1 vaccines safe for pregnant women, say Canadian experts

After discussion with the Public Health Agency of Canada, and based on the evidence for other adjuvanted vaccines as well as experience around the world to date with the adjuvanted H1N1 vaccine, Canadian experts say that both the adjuvanted and non-adjuvanted H1N1 vaccines are safe for pregnant women.

23 Oct 2009

Applied Biosystems announces the global availability of its 3500 Series Genetic Analyzer

Applied Biosystems, part of Life Technologies Corporation, today announced the global commercial availability of a new capillary electrophoresis (CE) sequencing system. The 3500 Series Genetic Analyzer builds on Applied Biosystems’ industry-leading CE sequencing systems, with state-of-the-art advancements, setting significant new standards for throughput, data quality and ease of use.

22 Oct 2009

SAEC to collaborate with HMORN to improve the safe use of drugs

The International Serious Adverse Events Consortium (SAEC) announced today it will collaborate with the HMO Research Network (HMORN) to improve the safe use of drugs by exploring why the genetic makeup of some individuals makes them more likely to experience serious drug-related adverse events (SAEs).

22 Oct 2009

£17,000 grant to university researcher for breast cancer research

A researcher at the University of Sheffield is set to investigate whether women with a mutation in a gene that prevents folate (vitamin B9) working effectively may be at increased risk of breast cancer.

21 Oct 2009

Women without HOXA13 gene mutation need not be subjected to X-rays

Hugh S. Taylor, M.D., professor in the Department of Obstetrics, Gynecology & Reproductive Sciences at Yale, and colleagues have found that women without mutations of the HOXA13 gene do not need to be subjected to x-rays and other tests for a rare condition called hand-foot genital syndrome. The research is presented at the American Society for Reproductive Medicine (ASRM) scientific meeting in Atlanta, Georgia, October 17-21.

20 Oct 2009

Scientists find mechanism that protects neurons from calcium overload

Tsuruta et al. find that a lipid kinase directs a voltage-gated calcium channel's degradation to save neurons from a lethal dose of overexcitement. The study appears in the October 19, 2009 issue of the Journal of Cell Biology (www.jcb.org).

20 Oct 2009

First high-throughput analysis of Salmonella Typhi gene

For the first time, researchers are able to look at the need for every gene in a bacterial cell in a single experiment. The new method will transform the study of gene activity and the search for weaknesses in bacterial armouries.

19 Oct 2009

Researchers find the genetic mutation that is linked with changes in brain development

For decades, scientists have thought the faulty neural wiring that predisposes individuals to behavioral disorders like autism and psychiatric diseases like schizophrenia must occur during development. Even so, no one has ever shown that a risk gene for the disease actually disrupts brain development.

19 Oct 2009

New chromosomal abnormality in acute lymphoblastic leukemia

Researchers identified a new chromosomal abnormality in acute lymphoblastic leukemia (ALL) that appears to work in concert with another mutation to give rise to cancer. This latest anomaly is particularly common in children with Down syndrome.

19 Oct 2009

DKC establishes link between genetic mutation affecting telomerase function and human disease

The human genetic disease dyskeratosis congenita (DKC) is an autosomal dominant disease that leads to abnormalities in tissues with a rapid cell turnover - the skin, nails, bone marrow, lungs and gut. Patients with DKC experience life-threatening symptoms. Bone marrow failure increases their risk of fatal infections and cancer. Many die before the age of 30 and management of the disease is limited to trying to treat its symptoms.

19 Oct 2009

Research study provides supportive evidence for using ATR inhibitors in cancer therapy

A study published in the October issue of Nature Genetics demonstrates that loss of the tumor-suppressor protein p53, coupled with elimination of the DNA-maintenance protein ATR, severely disrupts tissue maintenance in mice.

19 Oct 2009

Findings may yield new treatments for COPD

A genetic mutation found in four children born with multiple abnormalities may provide insight into potential treatments for newborn lung distress and chronic obstructive pulmonary disease (COPD).

19 Oct 2009

Slavica BioChem scientists reverse multidrug resistance in lung cancer using small molecules

HTDS - The issuer's Serbia based operating subsidiary Slavica BioChem www.slavicabiochem.com brings attention to its Mindup Bioresearch cancer project working on molecular origins of lung cancer: prospects for personalized prevention and therapy. On October 8 2009, the company posted a filing on Pink Sheets titled MindUp Cancer Project.

15 Oct 2009

Genetic mutation implicated in breast and ovarian cancers could also have a role in causing heart failure: Study

A genetic mutation implicated in breast and ovarian cancers could also have a role in causing heart failure, according to a new study reported at the 95th annual Clinical Congress of the American College of Surgeons.

15 Oct 2009

University of North Carolina awarded grant to continue research on rare disease-causing gene mutations

The University of North Carolina at Chapel Hill has been awarded a five-year, $6.2 million renewal grant to continue its work as part of the National Institutes of Health's Rare Diseases Clinical Research Network (RDCRN).

14 Oct 2009

Researchers discover compounds that show promise as novel treatments for AIDS

While studying an HIV protein that plays an essential role in AIDS progression, researchers at the University of Pittsburgh School of Medicine have discovered compounds that show promise as novel treatments for the disease.

14 Oct 2009

SCID infants who receive early bone marrow transplants are likely to have fewer complications

Mention the words "bubble boy" and many will recall David Vetter, the kid with big eyes and a thick thatch of dark hair who died 25 years ago after spending almost the entire 12 years of his life in a germ-free, plastic bubble. David was born with severe combined immune deficiency, or SCID, a condition that robbed him of an immune system.

14 Oct 2009

Mutation News and Research

APC enzyme may be effective for treating amyotrophic lateral sclerosis

2009 Inspiration Gala raises $1.27 million for BC Cancer Foundation

Follow healthy lifestyle to overturn genetic predisposition to heart disease

Adjuvanted and non-adjuvanted H1N1 vaccines safe for pregnant women, say Canadian experts

Applied Biosystems announces the global availability of its 3500 Series Genetic Analyzer

SAEC to collaborate with HMORN to improve the safe use of drugs

£17,000 grant to university researcher for breast cancer research

Women without HOXA13 gene mutation need not be subjected to X-rays

Scientists find mechanism that protects neurons from calcium overload

First high-throughput analysis of Salmonella Typhi gene

Researchers find the genetic mutation that is linked with changes in brain development

New chromosomal abnormality in acute lymphoblastic leukemia

DKC establishes link between genetic mutation affecting telomerase function and human disease

Research study provides supportive evidence for using ATR inhibitors in cancer therapy

Findings may yield new treatments for COPD

Slavica BioChem scientists reverse multidrug resistance in lung cancer using small molecules

Genetic mutation implicated in breast and ovarian cancers could also have a role in causing heart failure: Study

University of North Carolina awarded grant to continue research on rare disease-causing gene mutations

Researchers discover compounds that show promise as novel treatments for AIDS

SCID infants who receive early bone marrow transplants are likely to have fewer complications

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

Latest News