Myocarditis News and Research

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In medicine (cardiology), myocarditis is inflammation of heart muscle (myocardium). It resembles a heart attack but coronary arteries are not blocked.

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Emergency physicians seek to correct myths, misinformation surrounding 'dry drowning'

Parents have been reading-;and sharing-;alarming reports of children who died or nearly died due to "dry drowning" over the past year. However, the use of that incorrect, nonmedical term has contributed to confusion about the true dangers of drowning in children and led to serious and fatal conditions being ignored after a "dry drowning" diagnosis was made, according to a special report in the June issue of Emergency Medicine News, published in the Lippincott portfolio by Wolters Kluwer.

7 Jun 2018

Opdivo plus low-dose Yervoy shows promising results in treating renal cell carcinoma patients

Bristol-Myers Squibb Company today announced patient-reported outcomes data from the Phase 3 CheckMate -214 trial in intermediate- and poor-risk patients with advanced renal cell carcinoma treated with the Immuno-Oncology combination Opdivo plus low-dose Yervoy versus sunitinib over a two-year follow-up period.

1 Jun 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

New technologies help seniors age in place — and not feel alone

Nancy Delano, 80, of Denver has no plans to slow down anytime soon. She still drives to movies, plays and dinners out with friends. A retired elder care nurse who lives alone, she also knows that "when you reach a certain age, emergencies can happen fast." So, when her son, Tom Rogers, talked to her about installing a remote monitoring system, she didn't hesitate.

12 Mar 2018

Scientists discover new treatment approach to curb severe myocarditis

The outcome of viral myocarditis is closely associated with the immune response of the affected individual. An inhibitor of the immunoproteasome, a protein degradation complex in immunocompetent cells, reduces the extent of the inflammation and thus also the damage to the heart during myocarditis.

22 Feb 2018

First-ever treatment for Merkel cell carcinoma receives approval in Japan

Merck KGaA, Darmstadt, Germany, and Pfizer Inc. today announced that the Japanese Ministry of Health, Labor, and Welfare (MHLW) has approved BAVENCIO (avelumab, genetically recombinant Injection 200mg/mL for intravenous use) as the first and only treatment indicated for curatively unresectable Merkel cell carcinoma (MCC), a rare and aggressive cancer, in Japan.

27 Sep 2017

Biologic substance APOSEC shows promise for healing dermal wounds

APOSEC is a substance obtained from white blood corpuscles and was developed by a research group led by thoracic surgeon Hendrik Jan Ankersmit, Head of the Christian Doppler Laboratory for Cardiac and Thoracic Diagnosis and Regeneration at MedUni Vienna.

3 Aug 2017

Study finds that immune factors have cardioproliferative effects

In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction. However, the inability to proliferate is not true for all animals, and even in mammals, cardiomyocyte proliferation is known.

30 May 2017

Study shows how immune cells drive heart damage in mice

A new study in mice reveals that eosinophils, a type of disease-fighting white blood cell, appear to be at least partly responsible for the progression of heart muscle inflammation to heart failure in mice.

16 Mar 2017

Zika virus may also cause serious cardiovascular complications, research shows

Zika also may have serious effects on the heart, new research shows in the first study to report cardiovascular complications related to this virus, according to data being presented at the American College of Cardiology's 66th Annual Scientific Session.

10 Mar 2017

Immune checkpoint cancer therapies may cause rare cardiac side effects linked to unexpected immune response

Combination therapy utilizing two approved immunotherapy drugs for cancer treatment may cause rare and sometimes fatal cardiac side effects linked to an unexpected immune response.

4 Nov 2016

VTT researchers develop new mobile device that helps prevent cerebral infarctions

VTT Technical Research Centre of Finland has developed a mobile app and thumb-size device that help to prevent cerebral infarctions at an early stage, during asymptomatic atrial fibrillation.

19 Sep 2016

Genetic testing worthwhile in sudden cardiac death

Genetic testing and family screening help to provide explanations for sudden cardiac death in children and young adults, shows a population-based study.

24 Jun 2016

Common viruses could produce mild to lethal cardiac injury

A review article has been published in the journal Current Pharmaceutical Design which provides an overview of therecent literature discussing the different clinical forms of heart disease resulting from virus infections including the prognosis, and current therapies.

2 Apr 2016

Distinctive gene 'signature' may lead to new way to diagnose Lyme disease

Researchers at UC San Francisco and Johns Hopkins may have found a new way to diagnose Lyme disease, based on a distinctive gene "signature" they discovered in white blood cells of patients infected with the tick-borne bacteria.

12 Feb 2016

Mylan releases Clozapine Orally Disintegrating Tablets in U.S.

Mylan N.V. today announced the U.S. launch of Clozapine Orally Disintegrating Tablets, 25 mg and 100 mg, the generic version of Jazz Pharmaceutical's FazaClo.

24 Nov 2015

Experts call on U.S. and Mexican governments to reduce risk of Chagas disease

Chagas disease -- the third most common parasitic infection in the world -- affects approximately 7.5 million people, mostly in Latin America. To help reduce outbreaks of this disease in their countries, the United States and Mexican governments should implement a range of programs as well as fund research for the development of Chagas vaccines and treatments, according to a new policy brief by tropical-disease and science policy experts at Rice University's Baker Institute for Public Policy.

3 Nov 2015

European cardiomyopathies registry shows higher than expected use of defibrillators, genetic testing

The most representative snapshot of real world practice in cardiomyopathies in Europe has shown a higher than expected use of defibrillators and genetic testing. The baseline results of the ESC's EORP Cardiomyopathy Registry Pilot are presented for the first time today at ESC Congress 2015.

2 Sep 2015

Research: HD-IL2 can be effective in mRCC patients pre-treated with VEGF-targeted agents

High-dose interleukin-2 can be effective in selected metastatic renal cell cancer patients pre-treated with VEGF-targeted agents, reveals research presented today at the ESMO Symposium on Immuno-Oncology in Geneva, Switzerland.

24 Nov 2014