Nanoparticle News and Research

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In nanotechnology, a particle is defined as a small object that behaves as a whole unit in terms of its transport and properties. It is further classified according to size: in terms of diameter, fine particles cover a range between 100 and 2500 nanometers, while ultrafine particles, on the other hand, are sized between 1 and 100 nanometers.

Nanoprobes with near-infrared persistent luminescence for in vivo imaging

In a new take on use of luminescent nanoparticles as cancer imaging probes, a team of investigators from several research institutes in Paris, France, has developed new metal-containing nanoparticles that emit light for several hours after they are initially excited.

14 Jun 2007

Trial shows nanoparticle-enabled thermal therapy safe for treating cancer

Several types of metal nanoparticles are capable of converting energy, such as that carried by near-infrared light or an oscillating magnetic field, into heat at a level high enough to kill tumors.

14 Jun 2007

Hybrid gold-dendrimer nanoparticles target and image tumors

Dendrimer nanoparticles, made of spherical, highly branched polymers, have shown promise as drug delivery vehicles capable of targeting tumors with large doses of anticancer drugs.

14 Jun 2007

Double-duty nanoparticles overcome drug resistance in tumors

Cancer cells, like bacteria, can develop resistance to drug therapy. In fact, research suggests strongly that multidrug resistant cancer cells that remain alive after chemotherapy are responsible for the reappearance of tumors and the poor prognosis for patients whose cancer recurs.

14 Jun 2007

New drug-delivery system using nanomaterials

Researchers at UCLA have successfully manipulated nanomaterials to create a new drug-delivery system that promises to solve the challenge of the poor water solubility of today's most promising anticancer drugs and thereby increase their effectiveness.

8 Jun 2007

Novel technologies show promise for future of gene transfer

Several new technologies that could significantly impact the future of gene transfer applications were presented at a conference at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

Nanoparticle delivery of insulin gene to fight juvenile diabetes developed

A safer method to deliver the insulin gene to diabetes patients using nanoparticles, was presented at the 10th Annual Meeting of the American Society of Gene Therapy (ASGT) in Seattle.

3 Jun 2007

MRI effective method for revealing anatomical details of soft tissues

Contrast agents can help to make these images even clearer and allow physiological processes to be followed in real time. Conventional gadolinium complexes currently used as MRI contrast agent cannot reveal anatomic structures.

1 Jun 2007

Targeted nanoparticles offer promising techniques for cancer treatment

Researchers in the laboratory of Mark E. Davis at the California Institute of Technology have been using small interfering RNA (siRNA), sometimes known as silencing RNA, to "silence" specific genes that are implicated in certain malignancies.

22 May 2007

Nanomedicine opens the way for nerve cell regeneration

The ability to regenerate nerve cells in the body could reduce the effects of trauma and disease in a dramatic way.

22 May 2007

Fluorescent nanoparticles open up new possibilities for cellular imaging

Scientists from the University of Twente, the Netherlands, have successfully exploited the optical properties of fluorescent nanoparticles to broaden the scope of single-cell microscopy.

9 May 2007

Nanoparticles for 'on-the-spot' virus detector

Chemical engineers from the University at Buffalo have collaborated with scientists from other institutions to solve a critical bottleneck in the transport and capture of virus nanoparticles, making possible a device that could rapidly sample and detect infectious biological agents, such as viruses.

4 May 2007

Nanoparticles found near plaque-filled arteries

Scientific evidence increasingly links arterial calcification to the presence of nanosized particles so small that some scientists question whether a nanoparticle can live and, if so, play a viable role in causing disease.

1 May 2007

Gold nanoparticles used as a simple "litmus test" for mercury

With gold nanoparticles, DNA and some smart chemistry as their tools, scientists at Northwestern University have developed a simple "litmus test" for mercury that eventually could be used for on-the-spot environmental monitoring of bodies of water, such as rivers, streams, lakes and oceans, to evaluate their safety as food and drinking water sources.

30 Apr 2007

Nanoparticle-based sensors sniff out and identify proteins

A team of scientists from the University of Massachusetts Amherst have created a kind of molecular nose that uses nanoparticle-based sensors to sniff out and identify proteins.

24 Apr 2007

Gold nanoparticles for early detection of cancer

By attaching gold nanoparticles - like tiny balls or rods- to cancer cells, earlier detection will be possible.

24 Apr 2007

BioForce Nanosciences sells Nano Enabler to Louisiana Tech

BioForce Nanosciences has announced the March sale of the Nano eNabler molecular printer to Louisiana Tech University in Ruston, Louisiana.

24 Apr 2007

Assessing exposure to airborne nanomaterials

New methods and tools for measuring exposure to airborne engineered nanomaterials will be required to protect the health of workers in nanotechnology-related jobs, estimated to total 10 million people by 2014, according to two occupational health experts writing in the inaugural issue of the journal Nanotoxicology.

18 Apr 2007

Nanoparticles could damage DNA and lead to cancer

Tissue studies indicate that nanoparticles, engineered materials about a billionth of a meter in size, could damage DNA and lead to cancer, according to research presented at the 2007 Annual Meeting of the American Association for Cancer Research.

18 Apr 2007

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

A cancer-suppressing gene has been successfully delivered into the tumors of stage 4 lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at The University of Texas M. D. Anderson Cancer Center.

18 Apr 2007

Nanoparticle News and Research

Further Reading

Nanoprobes with near-infrared persistent luminescence for in vivo imaging

Trial shows nanoparticle-enabled thermal therapy safe for treating cancer

Hybrid gold-dendrimer nanoparticles target and image tumors

Double-duty nanoparticles overcome drug resistance in tumors

New drug-delivery system using nanomaterials

Novel technologies show promise for future of gene transfer

Nanoparticle delivery of insulin gene to fight juvenile diabetes developed

MRI effective method for revealing anatomical details of soft tissues

Targeted nanoparticles offer promising techniques for cancer treatment

Nanomedicine opens the way for nerve cell regeneration

Fluorescent nanoparticles open up new possibilities for cellular imaging

Nanoparticles for 'on-the-spot' virus detector

Nanoparticles found near plaque-filled arteries

Gold nanoparticles used as a simple "litmus test" for mercury

Nanoparticle-based sensors sniff out and identify proteins

Gold nanoparticles for early detection of cancer

BioForce Nanosciences sells Nano Enabler to Louisiana Tech

Assessing exposure to airborne nanomaterials

Nanoparticles could damage DNA and lead to cancer

Nanoparticle delivery system delivers cancer-suppressing gene in M. D. Anderson trial

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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