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Study offers new hope for people with disabling Dupuytren's disease

Researchers at the Kennedy Institute and Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, working with clinicians at NHS Lothian, have found that injection of the anti-TNF drug adalimumab into Dupuytren's disease nodules results in the reduction of the cell characteristics responsible for progression of Dupuytren's disease.

9 Jul 2018

Study: Oxidative stress can be used against tumors to treat cancer

Oxidative stress can help tumors thrive, but one way novel cancer treatments work is by pushing levels to the point where it instead helps them die, scientists report.

21 Jun 2018

Study: Rheumatoid Arthritis patients with depression have increased risk of disease flare

Research from the Department of Inflammation Biology, School of Immunology & Microbial Sciences has shown there is an increased risk of disease flare in Rheumatoid Arthritis patients who suffer from depression.

19 Jun 2018

Combination of NSAIDs and TNF inhibitors linked to reduced radiographic progression in AS patients

Celecoxib combined with TNF inhibitors was associated with the greatest reduction in radiographic progression.

14 Jun 2018

Synthetic cannabis use may increase risk of heart attack and stroke

The warning follows their treatment of a 25 year old prison inmate who had no family history of heart disease or traditional cardiovascular risk factors, and who was left with a permanent disability.

8 Jun 2018

Researchers report on the sweet side of snake venom toxins

A bite from a lancehead snake can be fatal. Species in the family, found throughout Central and South America, have venom that can disrupt blood clotting and cause hemorrhage, strokes and kidney failure.

4 Jun 2018

Researcher develops nanoparticle-based tags to detect viruses and cancer with high sensitivity

How can we detect cancer and viruses with high sensitivity? Physical chemist Laura Fabris-;an associate professor in the Materials Science and Engineering Department at Rutgers, the State University of New Jersey, and principal investigator of the Fabris NanoBio Group-;is addressing this very question.

22 May 2018

Study: Psoriasis patients taking Humira show no change in aortic inflammation

An antibody used to treat the skin disease psoriasis and other chronic autoimmune diseases such as rheumatoid arthritis and inflammatory bowel disease has no effect on aortic inflammation – a key marker of future risk of major cardiovascular events – unlike other antibodies that target different aspects of the immune system.

18 May 2018

Expectant mothers may use RA drugs without increased health risks to unborn babies

A new study led by a team at the Research Institute of the MUHC in Montreal has revealed that pregnant women with rheumatoid arthritis may be able to use certain RA drugs without possible increased health risks to their unborn babies.

17 May 2018

Key metabolites shed by gut bacteria can help protect from inflammation, study finds

Researchers at Tufts University have elucidated a mechanism by which the "good" bacteria that reside in our gastrointestinal tract can help protect us from inflammation, and how their disruption (dysbiosis) can increase the susceptibility of the liver to more harmful forms of disease.

4 May 2018

New results reinforce COPAXONE 40 mg/mL as safe and effective for RMS patients

Teva Pharmaceutical Industries Ltd., today announced up to 7-year efficacy, safety and tolerability results from the Glatiramer Acetate Low-Frequency Administration (GALA) open-label extension study of COPAXONE (glatiramer acetate injection) 40 mg/mL administered subcutaneously three-times-a-week for the treatment of relapsing forms of multiple sclerosis (RMS).

28 Apr 2018

Common therapy options for psoriasis can help reduce coronary plaque, study shows

Late-breaking clinical science shows common therapy options for psoriasis (PSO)-a chronic inflammatory skin disease-can help reduce coronary plaque. The authors found that not only do the treatments reduce the volume of the plaque, but also the plaque becomes less inflammatory over time harboring fewer characteristics prone to rupture and cause a heart attack.

26 Apr 2018

Anti-TNF medications appear to be safe for use during pregnancy, study shows

Anti-tumor necrosis factor medications are effective in controlling chronic inflammatory diseases, but some physicians recommend that their patients discontinue them during pregnancy.

5 Apr 2018

Scientists discover new family of promising silver-based anti-cancer drugs

A new family of very promising silver-based anti-cancer drugs has been discovered by researchers in South Africa. The most promising silver thiocyanate phosphine complex among these, called UJ3 for short, has been successfully tested in rats and in human cancer cells in the laboratory.

26 Mar 2018

Levels of inflammatory biomarkers could predict effectiveness of ECT for people with depression

People with major depression that has not been well controlled by medications and who have a biomarker in their blood indicating a higher level of inflammation may benefit more than people with less inflammation from electroconvulsive therapy to ease symptoms of their depression, according to a new UCLA study.

6 Mar 2018

Researchers discover that activation of specific enzyme may help suppress tumor metastasis

To stop the spread of cancer, cancer cells must die. Unfortunately, many types of cancer cells seem to use innate mechanisms that block cancer cell death, therefore allowing the cancer to metastasize.

19 Feb 2018

Scientists discover adult endothelial stem cells capable of generating fully functional blood vessels

The proper function of blood vessels is essential to life: blood vessels are responsible for transporting oxygen-rich red blood cells, nutrients, and immune cells throughout the body, to name just a few functions. Defects in blood vessels can correspondingly lead to a variety of life-threatening diseases.

15 Feb 2018