Nephrectomy News and Research

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Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

17 Apr 2024

Immunotherapy drug extends overall survival in kidney cancer patients after surgery

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

27 Jan 2024

Donating a kidney can be safe for people living with HIV, study shows

Based on findings from a study published today in the journal The Lancet Regional Health - Americas, researchers at Johns Hopkins Medicine and three collaborating medical institutions suggest that people living with the human immunodeficiency virus (HIV) who donate a kidney to other people living with HIV (PLWH) have a low risk of developing end-stage kidney disease (ESKD) or other kidney problems in the years following the donation.

24 Jul 2023

Study shows encouraging results for robotic IVC thrombectomy

Kidney cancer is not always confined to the kidney. In advanced cases, this cancer invades the body's biggest vein, the inferior vena cava (IVC), which carries blood out of the kidneys back to the heart.

19 Aug 2022

Taking everolimus post-surgery can improve outcomes in patients with high-risk renal cell carcinoma

In a study of patients with high-risk renal cell carcinoma, those who took the drug everolimus daily for up to one year after surgery lived longer without their disease returning (recurrence-free survival, or RFS) than those who did not take everolimus, although the results narrowly missed the clinical trial's prespecified level for statistical significance.

4 Jun 2022

Risk of major complications for living kidney donors is minimal, study confirms

The risk of major complications for people who donate a kidney via laparoscopic surgery is minimal. That is the conclusion of a 20-year Mayo Clinic study of more than 3,000 living kidney donors.

25 Apr 2022

Direct effect of SARS-CoV-2 on the kidney

Researchers infected human-induced pluripotent-stem-cell (iPSC)-derived kidney organoids with SARS-CoV-2 to study the virus's direct effect on the kidney.

18 Jan 2022

Impact of acute kidney injury associated gene expression in human kidney cells

A new study attempts to perform a comparative single-cell census of human kidneys employing samples from individuals suffering from acute kidney injury and controls without the condition.

20 Dec 2021

RENAL nephrometry score may help predict which patients are suitable for nephron-sparing surgery

For most children with renal masses, the standard of care has long been to remove the entire affected kidney- which is the protocol for Wilms tumor, the most common kidney cancer in children.

6 Dec 2021

Researchers explore the impact of venous thromboembolism during surgery for renal cell carcinoma

Venous thromboembolism (VTE) refers to blood clots in the veins, which is a serious yet preventable medical condition and is often seen with advanced cancers.

14 Sep 2021

Study explores impact of surgical delay for renal cell carcinoma during COVID-19 pandemic

During the peak of the COVID-19 pandemic, several elective surgeries for renal cell carcinoma, the most common type of kidney cancer, were delayed with unknown impact on outcomes for patients.

12 Feb 2021

ACE inhibition in kidney could influence pathogenesis of SARS-CoV-2

The dynamics of angiotensin-converting enzyme 2 (ACE2) expression in the kidney could have implications for the infectivity and pathogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), say researchers.

24 Jun 2020

Living kidney donors have greater risk of developing hypertension

Compared with non-donors, living kidney donors face a higher risk of developing hypertension, which may have negative effects on their kidney function.

20 Sep 2019

Machine learning may augment diagnostics of kidney disease

Two new studies reveal that modern machine learning--a branch of artificial intelligence in which systems learn from data, identify patterns, and make decisions--may augment traditional diagnostics of kidney disease. The findings appear in an upcoming issue of JASN.

6 Sep 2019

New pain management program sends 92% cancer surgery patients home with no opioids

A specialized pain management program for patients who underwent robotic surgery for urologic cancers resulted in just eight percent going home with narcotics after discharge, compared to 100 percent who would have received them without this enhanced recovery protocol.

23 May 2019

Non-surgical management found to be feasible option for penetrating kidney trauma

Trauma is the sixth leading cause of death worldwide, and recent studies suggest that 16 percent of renal trauma occurs from a penetrating injury, such as a gunshot wound, stabbing or piercing injury from a car accident.

16 Jul 2018

Robotic partial nephrectomy offers better outcomes for patients with early kidney cancer

For patients with early kidney cancer, removing part of the kidney instead of the whole kidney is often a preferred treatment because the procedure can effectively remove tumors while preserving kidney function.

11 Jul 2018

Practicing with fake organs helps surgeon to perform complex cancer surgery

Anthony Camnetar remembers the first time he was told that he had von Hippel-Lindau syndrome, a rare genetic disorder.

7 Jun 2018

FDA approves first adjuvant treatment to reduce risk of kidney cancer recurrence

The U.S. Food and Drug Administration today approved Sutent (sunitinib malate) for the adjuvant treatment of adult patients who are at a high risk of kidney cancer (renal cell carcinoma) returning after a kidney has been removed (nephrectomy).

17 Nov 2017

Review of kidney cancer incidence in California signals end of a trend

A review of kidney cancer in California from 1988 through 2013 by the UC Davis Institute for Population Health Improvement has concluded that the high incidence of small tumors and early-stage disease observed in California from 1988 until about 2009 has declined and stabilized in recent years, signaling the end of a trend.

18 Aug 2017