Neuralgia News and Research

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Neuralgia is pain in one or more nerves that occurs without stimulation of pain receptor (nociceptor) cells. Neuralgia pain is produced by a change in neurological structure or function rather than by the excitation of pain receptors that causes nociceptive pain.

Important first step towards designing new therapies for shingles

A team of scientists at the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health (NIH), has identified a human protein that helps varicella-zoster virus, the cause of chickenpox and shingles, spread from cell to cell within the body.

20 Oct 2006

Treatment with intravenous and oral antiviral medications may help relieve nerve pain related to shingles

A small trial suggests that treatment with intravenous and oral antiviral medications may reduce the nerve pain that occurs following shingles, according to a study posted online today that will appear in the July 2006 print issue of Archives of Neurology.

9 May 2006

Obtaining and documenting informed patient consent prior to surgery

Obtaining and documenting informed patient consent prior to surgery is of vital importance, but both the process and documentation of consent can be inadequate.

3 May 2006

Computer program lets people with Trigeminal neuralgia diagnose themselves

Trigeminal neuralgia, or TN, is a disorder affecting the areas of the face where the trigeminal nerve's branches are distributed, including the lips, eyes, nose, scalp, forehead, and upper and lower jaws.

13 Apr 2006

Reduction in small-fiber nerves may underlie complex regional pain syndrome-I

Researchers at Massachusetts General Hospital (MGH) have found the first evidence of a physical abnormality underlying the chronic pain condition called reflex sympathetic dystrophy or complex regional pain syndrome-I (CRPS-I).

13 Feb 2006

Botox injections relieve severe facial pain

According to a doctor in Brazil the excruciating pain associated with inflammation of the trigeminal nerve of the head and face can be substantially relieved by injections of botulinum toxin A.

25 Oct 2005

Botulinum toxin successfully treats trigeminal neuralgia

There is another use for botulinum toxin which has brought relief to some who suffer from migraines and eye spasms. Botulinum toxin can also successfully treat intense facial pain called trigeminal neuralgia, according to a study published in the October 25, 2005, issue of Neurology

24 Oct 2005

Gamma Knife Stereotactic Radiosurgery (GKRS) is an effective treatment for trigeminal neuralgia

"This has proven to be a safe, effective treatment for trigeminal neuralgia patients, without the potential facial paralysis and long-term recovery experienced with conventional surgery," said Volker Stieber, M.D., co-director of the Gamma Knife Program at Wake Forest Baptist.

19 Oct 2005

Neurological complication may result from rapid withdrawal from pregabalin

A report in the July Annals of Neurology describes a serious adverse event experienced by a participant in a clinical trial that may raise a new caution about the use of antiepileptic drugs for conditions other than epilepsy.

6 Jul 2005

Stronger version of chickenpox vaccine cuts incidence and severity of shingles in older adults

In one of the largest adult vaccine clinical trials ever, researchers have found that an experimental vaccine against shingles (zoster vaccine) prevented about half of cases of shingles--a painful nerve and skin infection--and dramatically reduced its severity and complications in vaccinated persons who got the disease. The findings appear in the June 2 issue of The New England Journal of Medicine.

1 Jun 2005

Drug that reduces the pain of fibromyalgia and improves sleep

A study of a drug that reduces the pain of fibromyalgia and improves sleep is published by a University of Kentucky physician in the peer-reviewed journal, Arthritis & Rheumatism.

12 Apr 2005

Chronic pain treatments more effective when taken together

People suffering from chronic, debilitating pain caused by nerve damage or disease report better pain relief at lower doses of a combined drug treatment than from either drug administered individually, a new Queen’s study funded by the Canadian Institutes of Health Research (CIHR) shows.

3 Apr 2005

Patch therapy provides similar pain relief as oral medications for patients with osteoarthritis (OA) knee pain

Researchers from the Altoona Arthritis and Osteoporosis Center have announced that data presented at the 24th Annual Scientific Meeting of the American Pain Society suggest that patch therapy provides similar pain relief as oral medications for patients with osteoarthritis (OA) knee pain.

3 Apr 2005

Need for greater understanding of shingles

Results from a recent international survey reveal that most people are aware of herpes zoster -- more commonly known as shingles -- but do not truly understand the complexity of the condition or the potential impact it has on their overall health.

23 Feb 2005

Guideline evaluates treatments for postherpetic neuralgia

A new guideline from the American Academy of Neurology evaluates treatments for postherpetic neuralgia. The guideline is published in the September 28 issue of Neurology, the scientific journal of the American Academy of Neurology.

28 Sep 2004

Low-dose infusion of ketamine completely relieves pain of complex regional pain syndrome

Limited, low-dose infusions of a widely used anesthetic drug may relieve the often intolerable and debilitating pain of Complex Regional Pain Syndrome (CRPS), a Penn State Milton S. Hershey Medical Center researcher found.

23 Sep 2004

Indicators identify shingles patients who have an increased risk of developing persistent pain

Researchers have recently confirmed a set of indicators that, alone and in combination, identify shingles patients who have an increased risk of developing persistent pain after the shingles rash heals. Results and implications of their study will be presented in the May 11 issue of Neurology, the scientific journal of the American Academy of Neurology.

10 May 2004

Studies show pregabalin does not affect male reproductivity or interfere with oral contraceptives

Two studies presented today at the American Academy of Neurology (AAN) 56th Annual Meeting show that pregabalin, when used as an add-on treatment for epilepsy, does not affect male reproductive function or interfere with the effectiveness of oral contraceptives.

29 Apr 2004