Neuro oncology News and Research

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Researchers identify common molecular alteration in glioblastoma

Glioblastoma is the most aggressive manifestation of brain tumours. Due to its high invasive capacity and uncontrolled, infiltrating growth, it is particularly difficult to manage. Currently, the treatment for this disease consists of a combination of surgery (when possible), radiation and chemotherapy.

22 Feb 2016

West Cancer Center introduces promising new treatment method for brain cancer patients

Brain Cancer patients in the Mid-South now have a promising new treatment method at West Cancer Center. Optune™, a portable device using low intensity electric fields to inhibit cancer cell replication causing death of cancer cells, is the first FDA-approved therapy in more than a decade to show a significant extension in overall survival rates for newly diagnosed adult Glioblastoma Multiforme (GBM) patients.

11 Feb 2016

MYB-QKI fusion gene that drives pediatric low-grade gliomas poses a triple threat

Oncology researchers have discovered that an abnormal fused gene that drives pediatric brain tumors poses a triple threat, operating simultaneously through three distinct biological mechanisms—the first such example in cancer biology.

2 Feb 2016

New nanotechnology approach could transform gliomas from death sentence into treatable condition

An MRI contrast agent that can pass through the blood-brain barrier will allow doctors to detect deadly brain tumors called gliomas earlier, say Penn State College of Medicine researchers. This ability opens the door to make this fatal cancer treatable.

18 Dec 2015

Experimental drugs that modify cell metabolism also halt tumor growth

Experimental drugs that alter cell metabolism also halted tumor growth and extended survival in mice with cancers linked to changes in the same gene, according to a new study led by researchers at NYU Langone Medical Center, its Laura and Isaac Perlmutter Cancer Center and Massachusetts General Hospital.

15 Dec 2015

Gene may play role in protecting breast cancer patients from developing chemobrain

A team of researchers from the National University of Singapore has established that variation of a gene may have a role in protecting cancer patients from developing chemotherapy-induced cognitive impairment, commonly known as 'chemofog' or 'chemobrain'.

9 Dec 2015

TGen: PPF drug could help treat patients with deadly brain cancer

In a significant breakthrough, the Translational Genomics Research Institute has identified a drug, propentofylline or PPF, that could help treat patients with deadly brain cancer.

13 Nov 2015

Rabbit virus can be paired with existing drug to deliver more potent punch to brain tumor cells

A rabbit virus currently being developed for cancer therapy can be paired with one of several existing drugs to deliver a more potent punch to a deadly type of brain tumor cell, researchers have found.

7 Oct 2015

Innovative vaccine therapy shows promise against glioblastoma brain tumors

An innovative vaccine therapy developed at Roswell Park Cancer Institute is being tested in a multisite clinical trial involving 50 patients with newly diagnosed glioblastoma brain tumors. The phase II study, now accruing patients at both Roswell Park and the Cleveland Clinic, will assess the effectiveness of the SurVaxM vaccine in combination with standard chemotherapy as treatment for this often-fatal cancer.

10 Sep 2015

Brain tumor is not always the death sentence

Only half of brain cancers actually start in the brain. The rest - as in the case of former president Jimmy Carter - are metastatic tumors from cancer that originated elsewhere in the body.

29 Aug 2015

BET inhibitors can cause molecular changes in neurons, lead to memory loss in mice

Cancer researchers are constantly in search of more-effective and less-toxic approaches to stopping the disease, and have recently launched clinical trials testing a new class of drugs called BET inhibitors. These therapies act on a group of proteins that help regulate the expression of many genes, some of which play a role in cancer.

25 Aug 2015

MGH study reveals effects of combined radiation and chemotherapy on the brain tissue of glioblastoma patients

A study from Massachusetts General Hospital Cancer Center researchers - the first to examine the effects of combined radiation and chemotherapy on the healthy brain tissue of glioblastoma patients - reveals not only specific structural changes within patients' brains but also that the effect of cancer therapy on the normal brain appears to be progressive and continues even after radiation therapy has ceased.

18 Aug 2015

Regulation of tumor microenvironment may offer alternate method for cancer treatment

Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.

18 Aug 2015

California Initiative to Advance Precision Medicine selects two demonstration projects

Two demonstration projects that aim to yield quick results for patients have been selected by the new California Initiative to Advance Precision Medicine, a public-private effort launched by Governor Edmund G. Brown Jr.

4 Aug 2015

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

DNA double-strand breaks (DSBs) are the worst possible form of genetic malfunction that can cause cancer and resistance to therapy. New information published this week reveals more about why this occurs and how these breaks can be repaired.

4 Aug 2015

Researchers make significant progress in improving survival of adult patients with low-grade gliomas

Using clinical data collected over the past decade through a U.S. cancer registry, researchers at the University of California, San Diego School of Medicine demonstrated that significant strides have been made in improving the survival of adult patients with low-grade gliomas, a slow-growing yet deadly form of primary brain cancer.

2 Jul 2015

Scientists find new way of classifying brain cancers

Not all brain cancers are the same but together they represent a deadly disease that has been difficult to identify and treat. Scientists at multiple institutions have found a new way of classifying brain cancers that could very well change how the illness is diagnosed and treated.

11 Jun 2015

Scientists and clinicians from across the UK come together to address treatment of brain tumors

In an exciting step forward to finding a cure for brain tumours, which kill more children and adults under the age of 40 than any other cancer, the national charity Brain Tumour Research brought together a group of leading brain tumour scientists and clinicians to help accelerate vital research into this devastating disease.

11 Jun 2015

New approach to classifying brain tumors could lead to significant improvements in diagnosis, treatment

A Case Comprehensive Cancer Center brain surgeon and neurosurgery professor is among the primary authors of a new approach to classifying tumors that could lead to significant improvements in their diagnosis and treatment. The research and recommendations appear online June 10 in The New England Journal of Medicine.

11 Jun 2015

Experts examine latest evidence-based medicine in treating metastatic brain and spinal cancer

Experts from around the country will join faculty experts from the University of Louisville's James Graham Brown Cancer Center, a part of KentuckyOne Health, to look at the latest evidence-based medicine in treating metastatic cancer of the central nervous system.

11 Jun 2015

Neuro oncology News and Research

Researchers identify common molecular alteration in glioblastoma

West Cancer Center introduces promising new treatment method for brain cancer patients

MYB-QKI fusion gene that drives pediatric low-grade gliomas poses a triple threat

New nanotechnology approach could transform gliomas from death sentence into treatable condition

Experimental drugs that modify cell metabolism also halt tumor growth

Gene may play role in protecting breast cancer patients from developing chemobrain

TGen: PPF drug could help treat patients with deadly brain cancer

Rabbit virus can be paired with existing drug to deliver more potent punch to brain tumor cells

Innovative vaccine therapy shows promise against glioblastoma brain tumors

Brain tumor is not always the death sentence

BET inhibitors can cause molecular changes in neurons, lead to memory loss in mice

MGH study reveals effects of combined radiation and chemotherapy on the brain tissue of glioblastoma patients

Regulation of tumor microenvironment may offer alternate method for cancer treatment

California Initiative to Advance Precision Medicine selects two demonstration projects

MD Anderson scientists reveal role of metabolic enzyme fumarase in DNA repair

Researchers make significant progress in improving survival of adult patients with low-grade gliomas

Scientists find new way of classifying brain cancers

Scientists and clinicians from across the UK come together to address treatment of brain tumors

New approach to classifying brain tumors could lead to significant improvements in diagnosis, treatment

Experts examine latest evidence-based medicine in treating metastatic brain and spinal cancer

Cancer Research eBook

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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