Neurodegenerative Disease News and Research

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Scientists find disparities in regulation of transposons between humans and non-human primate cells

Researchers at the Salk Institute for Biological Studies have, for the first time, taken chimpanzee and bonobo skin cells and turned them into induced pluripotent stem cells, a type of cell that has the ability to form any other cell or tissue in the body.

24 Oct 2013

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

he major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the unsolved mysteries of AD is how ApoE4 causes the risk for the incurable, neurodegenerative disease.

22 Oct 2013

Screening tool shows promise for Parkinson’s sleep disturbance

Researchers have developed a sleep questionnaire for screening the range of sleep disturbances experienced by patients with Parkinson’s disease.

21 Oct 2013

New approach could help identify specific gene mutations linked to increased disease risk

Researchers at the University of California, San Diego School of Medicine have developed a new way to parse and understand how special proteins called "master regulators" read the genome, and consequently turn genes on and off.

13 Oct 2013

U.S. Research Will "Pay Dearly" For Shutdown, ASCB Warns

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9 Oct 2013

Study points to new pathways, targets for novel therapies to treat neurodegenerative diseases

Scientists at the Montreal Neurological Institute and Hospital-The Neuro, McGill University, have made important discoveries about a cellular process that occurs during normal brain development and may play an important role in neurodegenerative diseases.

9 Oct 2013

Scientists identify new drug for inherited form of cancer with no known cure

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure.

3 Oct 2013

Three UC Irvine scientists receive prestigious 2013 NIH New Innovator Awards

UC Irvine scientists Aaron Esser-Kahn, Sunil Gandhi and Ali Mortazavi have been named recipients of the prestigious 2013 National Institutes of Health Director's New Innovator Awards.

1 Oct 2013

Biochemists discover promising vitamin D-based treatment that halts or reverse MS

A diagnosis of multiple sclerosis (MS) is a hard lot. Patients typically get the diagnosis around age 30 after experiencing a series of neurological problems such as blurry vision, wobbly gait or a numb foot. From there, this neurodegenerative disease follows an unforgiving course.

1 Oct 2013

Biochemists discover promising vitamin D-based treatment that can halt MS

A diagnosis of multiple sclerosis is a hard lot. Patients typically get the diagnosis around age 30 after experiencing a series of neurological problems such as blurry vision, wobbly gait or a numb foot. From there, this neurodegenerative disease follows an unforgiving course.

29 Sep 2013

MGH researchers identify rare gene mutations that appear to cause late-onset AD

Massachusetts General Hospital (MGH) researchers have identified and validated two rare gene mutations that appear to cause the common form of Alzheimer's disease (AD) that strikes after the age of 60.

25 Sep 2013

Blood lipid marker may help predict risk for Parkinson's disease

A genetic mutation, known as GBA, that leads to early onset of Parkinson's disease and severe cognitive impairment (in about 4 to 7 percent of all patients with the disease) also alters how specific lipids, ceramides and glucosylceramides are metabolized. Mayo Clinic researchers have found that Parkinson's patients who do not carry the genetic mutation also have higher levels of these lipids in the blood. Further, those who had Parkinson's and high blood levels were also more likely to have cognitive impairment and dementia.

19 Sep 2013

Levels of certain fats in cerebral spinal fluid can predict patients with HIV, say scientists

Johns Hopkins scientists have found that levels of certain fats found in cerebral spinal fluid can predict which patients with HIV are more likely to become intellectually impaired.

12 Sep 2013

World's leading scientists to explore health benefits of Hydrogen Sulfide at conference

A gas associated with the smell of rotten of eggs is now being proven to have widespread health benefits. Hydrogen Sulfide is widely known as a poisonous and corrosive substance, but now a mounting body of evidence suggests it could be used in a wide range of treatments for some of the biggest health problems of our time. A conference hosted by the University of Exeter will bring together world-leading scientists to explore the emerging possibilities.

5 Sep 2013

Prana's PBT2 drug recognised as one of the most promising treatments under development

Prana Biotechnology, a leading global developer of first-in-class treatments for neurodegenerative disease, is pleased to announce Elsevier Business Intelligence has named clinical drug PBT2 as one of the Top 10 Neuroscience Projects to Watch.

3 Sep 2013

'Quest to Cure MSA in Honor of Rex Griswold' drives in-depth genomic investigation of rare nerve disorder

Rex Griswold, Vice President of Sales for Nestl- Waters North America, was a driving force at the company for more than two decades until Multiple System Atrophy (MSA) suddenly struck him.

31 Aug 2013

Blood test provides tool essential to trials of therapies for Huntington's disease

An assay designed to measure normal and abnormal forms of the huntingtin protein - the mutated form of which causes Huntington's disease - was successful in detecting levels of the mutant protein in a large multicenter study of individuals at risk for the devastating neurological disorder.

30 Aug 2013

Researchers identify possible treatment strategy for ALS and other neurodegenerative disorders

Researchers have tied mutations in a gene that causes amyotrophic lateral sclerosis and other neurodegenerative disorders to the toxic buildup of certain proteins and related molecules in cells, including neurons. The research, published recently in the scientific journal Cell, offers a new approach for developing treatments against these devastating diseases.

29 Aug 2013

Comprehensive test of biomarkers have prognostic and diagnostic value in Parkinson's disease

Perelman School of Medicine researchers at the University of Pennsylvania report the first biomarker results reported from the Parkinson's Progression Markers Initiative (PPMI), showing that a comprehensive test of protein biomarkers in spinal fluid have prognostic and diagnostic value in early stages of Parkinson's disease.

27 Aug 2013

Scientists identify specific type of receptor that may aid in treatment of AD, Parkinson’s disease

Scientists at Washington University School of Medicine in St. Louis have found a way that corrupted, disease-causing proteins spread in the brain, potentially contributing to Alzheimer's disease, Parkinson's disease and other brain-damaging disorders.

26 Aug 2013