Neurodegenerative Disorder News and Research

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Researchers develop new method for studying age-related brain disorders

Researchers at Lund University in Sweden have developed a new method for studying age-related brain disorders.

17 Aug 2022

New AI technology may aid in the discovery of therapeutic agents for neurodegenerative disorders

A research group from Nagoya University in Japan has developed an artificial intelligence for analyzing cell images that uses machine learning to predict the therapeutic effect of drugs.

25 Jul 2022

Study shows how tau protein, critical to Alzheimer's, turns from normal to diseased state

Alzheimer’s disease, the most common form of dementia, currently has no cure or effective therapy, in part due to gaps in our understanding of how the progressive neurodegenerative disorder arises in the brain.

8 Jul 2022

Gene defect underlying Krabbe disease causes degeneration of neurons directly, study finds

The gene defect underlying Krabbe disease causes degeneration of neurons directly, independent of its effects on other cell types, according to a new study publishing July 5th in the open-access journal PLOS Biology by Daesung Shin of the University at Buffalo, U.S. and colleagues.

5 Jul 2022

Elevated cerebrospinal fluid biomarkers of neuroinflammation in NeuroCOVID patients

A new research paper studied several biomarkers associated with neuronal injury, neuroinflammation, and neurodegeneration in NeuroCOVID adults who experienced a CNS syndrome during acute SARS-CoV-2 infection.

4 Jul 2022

Study uncovers new gene that increases Alzheimer's disease risk in women

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S. Scientists have discovered some genetic variants that increase the risk for developing Alzheimer's; the most well-known of these for people over the age of 65 is the APOE ε4 allele.

30 Jun 2022

Researchers discover two important novel aspects of APOE4 gene in Alzheimer's patients

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia, affecting more than 5.8 million individuals in the U.S.

23 Jun 2022

Study: Glaucoma diagnosis not associated with steeper rates of cognitive decline

Previous studies have looked for links between glaucoma-;a neurodegenerative disorder that's the leading cause of irreversible blindness-;and cognitive function, but they've generated mixed results.

22 Jun 2022

‘Sting’ protein’s response to clean up damaged brain cells may accelerate Parkinson’s disease progression

In studies with mouse and human tissue, as well as live mice, Johns Hopkins Medicine researchers report that a snag in the normal process of cleaning up broken DNA in brain cells may hasten the progression of Parkinson's disease.

19 May 2022

Cannabidiol for Parkinson's disease symptom management

Scientists have published a review study in the Journal for Nurse Practitioners that has focussed on various aspects of the use of cannabidiol in Parkinson's.

17 May 2022

Incorporating views of patients with Parkinson's disease in clinical research proven effective

Although there is a growing trend to involve patients in clinical research, specific guiding principles for engaging individuals with Parkinson's disease have not been established.

11 May 2022

Little-known protein found to play a role in common neurodegenerative disorder

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

20 Apr 2022

Researchers find possible window of opportunity to target astrocyte abnormalities during ALS treatment

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder that affects as many as 30,000 people in the United States, with 5,000 new cases diagnosed each year. It weakens muscles over time, impacting physical function and ultimately leading to death.

29 Mar 2022

Novel optobiological system may shine light on protein aggregation in Parkinson's disease

A novel system to control protein aggregation in a model of Parkinson's disease may answer longstanding questions about how the disease begins and spreads, according to a new study published March 9th in the open-access journal PLOS Biology by Abid Oueslati of Laval University, Quebec, Canada, and colleagues.

23 Mar 2022

Researchers identify a gene that could prevent Parkinson’s disease

Parkinson's disease is a neurodegenerative disorder characterized by the destruction of a specific population of neurons: the dopaminergic neurons.

17 Mar 2022

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

The diagnosis of Parkinson's disease (PD) is currently based on consensus clinical criteria. A novel study reported in the Journal of Parkinson's Disease has found that the presence of neuronal deposits of the biomarker phosphorylated alpha-synuclein (p-syn) in the brain and the skin of patients with PD distinguishes them from individuals with symptoms of parkinsonism due to the accumulation of another protein, tau.

15 Mar 2022

Researchers identify motor neuron toxin associated with ALS

An international team of investigators has discovered that an inorganic polyphosphate released by nerve cells known as astrocytes in people with amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) contributes to the motor neuron death that is the signature of these diseases.

10 Mar 2022

Artificially intelligent olfactory system may diagnose Parkinson’s disease at an early stage

A couple of years ago, a woman named Joy Milne made headlines when scientists discovered that she could "smell" Parkinson's disease (PD) on people with the neurodegenerative disorder.

23 Feb 2022

New insights into why women develop Alzheimer's symptoms earlier and exhibit faster memory decline

A joint study by Nanyang Technological University, Singapore and National University of Singapore (NUS) scientists has examined why, in mice, female brains are more predisposed to Alzheimer's disease and other neurodegenerative diseases.

16 Feb 2022

Progression of Alzheimer's disease is linked to oxidative brain damage, research confirms

Increased oxidative damage is linked to neurodegenerative disorders such as Alzheimer's disease (AD). Even though the pathophysiology of AD has been widely investigated, the likely relationship between mitochondrial dysfunction and the disease remains largely unknown.

14 Feb 2022