Neurogenesis News and Research

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Neurogenesis (birth of neurons) is the process by which neurons are generated. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain.

Study searches for the origins of depressive symptoms in Huntington's disease

About 40% of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

Study sheds light on design of pharmacological strategies to treat depression in Huntington's disease

About 40 % of the affected patients with Huntington's disease -a neurodegenerative pathology- show depression symptoms, even in early stages before the apparition of the typical motor symptoms of the disease.

31 May 2019

New neurons continue to form in old age, even in people with Alzheimer's disease

In a new study from the University of Illinois at Chicago, researchers examining post-mortem brain tissue from people ages 79 to 99 found that new neurons continue to form well into old age.

25 May 2019

Three studies show how tumors hijack the immune system to develop radiotherapy resistance

More than a decade ago, radiation oncologists noticed a nifty phenomenon: Sometimes radiation used locally against a tumor could excite the immune system to attack cancer systemically throughout the body.

17 Apr 2019

Neuronal transport factor detects its target transcripts in more complex manner than previously thought

A team of scientists from Helmholtz Zentrum München and the University of Ulm has discovered that the neuronal transport factor Staufen2 scans and binds to its target transcripts in a much more complex manner than previously thought.

16 Apr 2019

Active lifestyle influences regenerative capacity of neurons after spinal cord injury

The influence of an active lifestyle on the regenerative capacity of the peripheral nervous system, that is, the set of cranial and spinal nerves that control motor and sensory functions, is described here for the first time, explains Ángel Barco, who has led the participation of the Institute of Neurosciences UMH-CSIC, in Alicante, in this international study.

11 Apr 2019

Single lineage of stem cells contributes to lifelong hippocampal neurogenesis in mice

Scientists once thought that mammals entered adulthood with all of the neurons they would ever have, but studies from the 60s found that new neurons are generated in certain parts of the adult brain and pioneering studies from the 90s helped identify their origins and function.

29 Mar 2019

Marijuana use during pregnancy may increase psychosis risk in offspring

Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life, suggests new research from Washington University in St. Louis.

28 Mar 2019

Discovery could lead to new drugs for pain conditions

If a particular protein is missing during the fetal stage, no neurons develop that convey pain, temperature and itch, a study from Karolinska Institutet in Sweden published in the journal Cell Reports shows. The discovery can eventually lead to new drugs for pain conditions.

27 Mar 2019

Brain can produce new cells even at the age of 90

For the first time, researchers have proven that the brain is capable of producing new nerve cells even at the age of 90 and above.

26 Mar 2019

Akna protein plays a key role in the regulation of neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine.

22 Feb 2019

Scientists uncover new mechanisms regulating neural stem cells

The use of stem cells to repair organs is one of the foremost goals of modern regenerative medicine. Scientists at Helmholtz Zentrum München and Ludwig Maximilian University of Munich have discovered that the protein Akna plays a key role in this process.

21 Feb 2019

New research shows adult neurogenesis does not persist in the human hippocampus

The generation of new neurons in the human hippocampus strongly decreases from childhood to almost undetectable levels in adults. It can therefore be stated that neurogenesis in the human hippocampus is almost non-existent, as opposed to what has been thought in recent decades.

29 Jan 2019

New lessons learned from adult neurogenesis debate

Since the 1960s, consensus about whether human adults generate new neurons with age has swayed back and forth from "yes, at least in some places in the brain" to "no, not at all."

25 Jan 2019

Neurons produced after a stroke fail to develop properly, research finds

Mice produce new neurons in the hippocampus following a stroke that fail to develop properly, finds new research published in JNeurosci. Intervening in the production of these cells may help to mitigate stroke-induced memory impairments.

From Society for Neuroscience 9 Jan 2019

Study provides new insight into generation of new neurons in adulthood

Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada, and Slovenia, have discovered a novel and unexpected function of nestin, the best known marker of neural stem cells.

3 Jan 2019

Study investigates why mammals' sense of smell deteriorates in old age

As mammals age, their sense of smell deteriorates. In a study published in the journal 'Cell Reports', an interdisciplinary research team at Helmholtz Zentrum München and the University Medical Centre Mainz investigated why this is the case.

19 Dec 2018

Novel approach gives new insights into formation of neurons in mammalian adult brain

A team of researchers at Baylor College of Medicine, the Texas Heart Institute and Texas Children's Hospital has developed a powerful new approach to understand the formation of new neurons in the mammalian adult brain.

5 Dec 2018

Expanding the knowledge about hippocampus to better understand cognitive deficits in MS

A recent article by a team of international experts on multiple sclerosis (MS) underscores the importance of expanding the knowledge base about the hippocampus in order to better understand the genesis of cognitive deficits and develop new treatment strategies.

17 Oct 2018

Researchers decode regulatory impact on neuronal survival of small non-coding RNA molecule

An interdisciplinary and international research group led by Dr. Volker Busskamp from the Center for Regenerative Therapies Dresden at the TU Dresden has decoded the regulatory impact on neuronal survival of a small non-coding RNA molecule, so-called miRNA, at the highest resolution to date.

4 Oct 2018