Neurogenesis News and Research

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Neurogenesis (birth of neurons) is the process by which neurons are generated. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain.

Liver X receptor beta offers new hope in treating depression and anxiety

Liver X receptor beta (LXRβ) shows potential in reducing depression and anxiety by improving neurogenesis, reducing neuroinflammation, and enhancing cognitive and emotional function. More research on LXR agonists could reveal new treatments for mental health disorders.

8 Oct 2024

LXRβ emerges as a promising target for depression and anxiety treatments

In a state-of-the-art Bench to Bedside review published in the journal Brain Medicine (Genomic Press), researchers Dr. Xiaoyu Song and Professor Jan-Åke Gustafsson from the University of Houston and Karolinska Institutet (Sweden) shed light on the therapeutic potential of liver X receptor beta (LXRβ) in treating depression and anxiety.

4 Oct 2024

Leptin variations may influence brain health and dementia development

New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

18 Sep 2024

Study explores microglial response to chronic hyponatremia and rapid sodium correction

Low serum sodium concentrations in blood are called hyponatremia, a prevalent clinical electrolyte disorder.

18 Sep 2024

Scientists reveal how DNA methylation drives astrocytes to become stem cells, unlocking new potential for brain repair

Researchers have discovered that DNA methylation is crucial for reprogramming astrocytes into stem cells in the adult mouse brain, especially after ischemic injury, with potential implications for regenerative medicine.

6 Sep 2024

Brief periods of light-intensity exercise can boost children's cerebral blood flow

Cognitive functions, also known as intellectual functions, encompass thinking, understanding, memory, language, computation, and judgment, and are performed in the cerebrum.

26 Aug 2024

Maternal gut bacteria linked to changes in fetal brain metabolism

The impact of Bifidobacterium breve's presence in the maternal gut during pregnancy on fetal brain metabolism.

23 Aug 2024

Epigenetic reprogramming and hypothalamic changes in metabolic syndrome

Metabolic syndrome (MetS) is a multifaceted disorder that impacts approximately 20–25% of the global population.

30 Jul 2024

Is air pollutant exposure during pregnancy associated with infant cerebral palsy risk?

The association between prenatal exposure to ambient air pollution during the pregnancy and the risk of cerebral palsy in the infant.

12 Jul 2024

Animal model sheds light on the role understudied brain organ in repairing stroke damage

University of Cincinnati researchers have pioneered an animal model that sheds light on the role an understudied organ in the brain has in repairing damage caused by stroke.

9 Jul 2024

Understanding the role of vaccination in mitigating long COVID brain fog

Since the outset of the COVID-19 pandemic, 10 to 30 per cent of the general population has experienced some form of virus-induced cognitive impairment, including trouble concentrating, brain fog or memory loss.

27 Jun 2024

Restoring youthful TERT levels reverses aging phenotypes in preclinical models

Researchers at The University of Texas MD Anderson Cancer Center have demonstrated that therapeutically restoring 'youthful' levels of a specific subunit of the telomerase enzyme can significantly reduce the signs and symptoms of aging in preclinical models.

21 Jun 2024

New AARF-D award supports Temple researchers to explore synapse function in the aging brain

Late-life depression is a major risk factor for Alzheimer's disease, in particular because it accelerates progression from mild cognitive impairment to dementia.

12 Jun 2024

Curcumin nanoparticles show promise in treating neurodegenerative diseases

Review demonstrates curcumin's neuroprotective effects in neurodegenerative diseases, enhancing its potential through innovative nanoparticle formulations. This advancement could significantly improve treatments for diseases like Parkinson's, Alzheimer's, and Multiple Sclerosis.

6 Jun 2024

Novel catalog of gene-isoform variation unveiled in the developing human brain

A team led by researchers at UCLA and the University of Pennsylvania has produced a first-of-its kind catalog of gene-isoform variation in the developing human brain.

23 May 2024

Study demonstrates link between disrupted developmental dopamine signaling and ASD

Recent evidence suggests that dopamine plays a crucial role in neural development. In a novel study, investigators demonstrated the link between disrupted developmental dopamine signaling and autism spectrum disorder (ASD).

16 May 2024

Physical activity can be beneficial for cognitive development of children with ADHD

Attention Deficit Hyperactivity Disorder can impact many common childhood milestones and cognitive processes, such as decision-making, inhibitory control, language development, and goal-setting. Studies by University of Rhode Island kinesiology Assistant Professor Nicole Logan have shown that physical activity can be beneficial for the development of such cognitive processes, particularly in children who may have room to improve in those areas.