Neurogenesis News and Research

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Neurogenesis (birth of neurons) is the process by which neurons are generated. Most active during pre-natal development, neurogenesis is responsible for populating the growing brain.

Environmental stressors linked to fetal brain development challenges

Review article in the journal Antioxidants explores the impact of environmental factors on fetal and neonatal brain development, emphasizing the role of inflammation and oxidative stress from maternal stressors.

15 Apr 2024

Poverty and low socioeconomic status affect cognitive development, mental health

What determines mental health, school performance, and even cognitive development? A new review in De Gruyter's Reviews in the Neurosciences suggests that poverty and low socioeconomic status (SES) are key contributory factors.

15 Apr 2024

Genetic link between PTSD and Alzheimer's debunked in veterans study

Study reveals that the genetic risk factor for Alzheimer’s disease, APOE ε4, does not increase PTSD risk among combat veterans, challenging the previously suggested link between PTSD and future dementia.

7 Apr 2024

Mitochondrial fusion critical for adult neurogenesis and brain circuit refinement

Nerve cells (neurons) are amongst the most complex cell types in our body. They achieve this complexity during development by extending ramified branches called dendrites and axons and establishing thousands of synapses to form intricate networks.

5 Apr 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Vitamin D shows promise in targeting aging's biological mechanisms, study finds

What is currently known about the potential effect of vitamin D (VitD) on modulating some hallmarks of aging.

26 Mar 2024

Review suggests the middle-aged brain could provide a window into future cognitive health

The middle-aged brain could provide a window into future cognitive health, researchers write in a review publishing March 19 in the journal Trends in Neurosciences.

19 Mar 2024

Even low levels of leisure-time physical activity can prevent stroke in the long term

Recently, scientists conducted a systematic review and metaanalysis to understand better whether different levels of leisure-time physical activity (LTPA) prevent stroke.

6 Mar 2024

Prenatal exposure to nicotine could increase risk of behavioral disorders in newborns, study finds

Although several studies have linked smoking during pregnancy with neurodevelopmental disorders, the results of behavioral experiments in mice prenatally exposed to nicotine have been inconsistent.

5 Mar 2024

COVID-19's lasting impact on smell and brain health unveiled

Study reviews the impact of COVID-19 on olfactory dysfunction and its link to neurocognitive disorders, highlighting MRI findings and potential treatments for smell loss.

12 Feb 2024

Can mushrooms improve your memory?

The associations between mushroom intake and cognitive performance.

29 Jan 2024

Long-term expansion and self-organization of human fetal brain organoids

Researchers establish fetal brain organoids as a versatile platform for brain cancer modeling.

12 Jan 2024

UW-Madison technology unveils autism gene's impact on early brain structure

Technology developed at the University of Wisconsin–Madison to grow "rosettes" of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

20 Dec 2023

Brainoware: A breakthrough AI approach using brain organoids for advanced computation

Study in Nature Electronics introduces "Brainoware," an innovative AI hardware approach using brain organoid neural networks for complex tasks like speech recognition and nonlinear dynamic predictions, demonstrating significant potential in AI development.

12 Dec 2023

Tat-heat shock protein 10 could rejuvenate aging brains

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 22, entitled, "Tat-heat shock protein 10 ameliorates age-related phenotypes by facilitating neuronal plasticity and reducing age-related genes in the hippocampus."

12 Dec 2023

Long-term physical activity can prevent obesity-induced cognitive decline

Obesity is a major risk factor for cardiovascular metabolic diseases and neurodegenerative diseases such as dementia.

30 Nov 2023

Genetic mutation in OXR1 gene linked to brain development issues

Study investigates the effects of a loss-of-function mutation in the OXR1 gene on neurodevelopment and cellular functions in the human brain. The research shows that OXR1 deficiency impairs neural differentiation, increases sensitivity to oxidative stress, and alters histone methylation, impacting brain development and potentially contributing to neurological disorders.

27 Nov 2023

Stem-cell-derived brain cells hold promise for Alzheimer's, Parkinson's research

Researchers at the University of Wisconsin–Madison have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer's and Parkinson's diseases and used the discovery to grow the neurons from stem cells for the first time.

17 Nov 2023

Study reveals early role of SYNGAP1 gene in brain development

The gene SYNGAP1, the variants of which are top risk factors for Autism Spectrum Disorder (ASD), has previously unappreciated effects on the developing brain, according to a new study published in Nature Neuroscience.

9 Nov 2023

TIMP2 protein identified as key player in brain plasticity and memory

Researchers explored the molecular and cellular processes regulated by tissue inhibitor of metalloproteinases-2 (TIMP2) in the extracellular matrix (ECM) of the adult brain hippocampus.

6 Nov 2023