Neuroimmunology News and Research

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Researchers identify key regulators involved in genesis of multiple sclerosis lesions

By means of CRISPR screening, LMU researchers have provided the first ever comprehensive molecular characterization of T cell infiltration into the central nervous system of people with MS.

22 Sep 2023

N-acetylglucosamine reduces multiple inflammation and neurodegeneration markers in MS patients

UCI researchers have found that a simple sugar, N-acetylglucosamine, reduces multiple inflammation and neurodegeneration markers in people who suffer from multiple sclerosis (MS).

14 Sep 2023

Study finds evidence of SARS-CoV-2 exposure in many patients with postviral syndrome

Researchers investigated immunologic and clinical findings indicative of SARS-CoV-2 exposure among individuals with postviral syndrome.

29 Aug 2023

41% of people with post-viral syndrome had evidence of SARS-CoV-2 exposure

Millions of Americans were exposed to SARS-CoV-2, the virus that causes COVID-19, early in the pandemic but could not get diagnosed due to testing limitations.

23 Aug 2023

Researchers discover possible new biomarker of MS-like autoimmune disease

It has been known for several years that the diagnosis "multiple sclerosis" conceals a whole range of different illnesses, each requiring customized treatment. Researchers at the University of Basel and the University Hospital of Basel have now described a possible new MS-like disease and explained how to diagnose it.

8 Aug 2023

Study reveals biologically validated imaging-based evidence of medically induced myelin repair

A decade after UC San Francisco scientists identified an over-the-counter antihistamine as a treatment for multiple sclerosis, researchers have developed an approach to measure the drug's effectiveness in repairing the brain, making it possible to also assess future therapies for the devastating disorder.

13 Jun 2023

Immune system's ability to respond to spinal cord injuries diminishes with age, study suggests

New research suggests that the immune system's ability to respond to spinal cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

2 Jun 2023

Research finds more depressed patients with activated immune systems than previously estimated

New research from the Institute of Psychiatry, Psychology & Neuroscience (IoPPN) at King's College London has used an assessment of gene expression involved in the immune response to show that there could be more patients with MDD with activated immune systems than research has previously estimated.

30 May 2023

Immune system’s ability to respond to spinal cord injuries reduces with age, research suggests

New research suggests that the immune system’s ability to respond to spinal-cord injuries diminishes with age – and identifies potential avenues to improve that response and help patients heal.

25 May 2023

Importance of analyzing the impact of life stressors on those with MS

A Michigan Medicine-led study finds that stressors across the lifespan -; including poverty, abuse and divorce -; are associated with worsening health and functional outcomes for people with multiple sclerosis.

25 May 2023

People with Long COVID neurological symptoms found to have differences in immune cell profiles and autonomic dysfunction

Twelve people with persistent neurological symptoms after SARS-CoV-2 infection were intensely studied at the National Institutes of Health (NIH) and were found to have differences in their immune cell profiles and autonomic dysfunction.

5 May 2023

Sleep disorders contribute to cognitive dysfunction in women with multiple sclerosis

For women with multiple sclerosis who report cognitive dysfunction -; one of the most common and disabling symptoms of the disease -; sleep disorders such as insomnia and sleep apnea may contribute to the perceived decline, a Michigan Medicine study suggests.

21 Mar 2023

MS relapse risk not likely to increase after fertility treatments, study finds

There's good news for those with multiple sclerosis (MS). A new study has found that female participants were no more likely to have a flare-up of the disease after receiving fertility treatments than they were before their treatments.

16 Mar 2023

UK HealthCare neurologist helps to compile an essential list of MS medications

Together with Multiple Sclerosis (MS) experts, biostatisticians and clinicians from across the globe, a UK HealthCare neurologist has helped compile an essential list of MS medications for patients in resource-poor settings.

3 Mar 2023

Does COVID-19 accelerate the worsening of clinical disabilities in multiple sclerosis patients?

The researchers investigated the impact of coronavirus disease 2019 (COVID-19) on the progression of clinical disability in multiple sclerosis patients.

24 Feb 2023

CHLA launches first clinical trial for Down syndrome regression disorder with $5.3 million NIH grant

Children's Hospital Los Angeles has launched the first clinical trial for Down syndrome regression disorder (DSRD), a rare and debilitating condition that affects adolescents and young adults with Down syndrome.

23 Jan 2023

Unexpected declines in cognitive performance after epilepsy surgery

In severe epilepsies, surgical intervention is often the only remedy - usually with great success. While neuropsychological performance can recover in the long term after successful surgery, on rare occasions, unexpected declines in cognitive performance occur.

22 Nov 2022

Research reveals why stem cell transplants are so successful in MS patients

Blood stem cell transplantation is a radical but highly effective therapy for multiple sclerosis. A study led by the University of Zurich has now examined in detail the way in which the treatment curbs the autoimmune disease and how the immune system regenerates afterwards.

10 Nov 2022

Long-term effects of SARS-CoV-2 on the brain

More profoundly than previously believed, the virus that causes COVID-19, SARS-CoV-2, can impact the brain for months after infection.

9 Nov 2022

Researchers find an innovative approach to improve waste clearance from the brain

Alzheimer's, Parkinson's and many other neurodegenerative diseases are marked by damaging clusters of proteins in the brain. Scientists have expended enormous effort searching for ways to treat such conditions by clearing these toxic clusters but have had limited success.