Neuropharmacology News and Research

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Study identifies brain energy metabolism dysfunction in neuropsychiatric disorders

A global collaborative research group comprising 131 researchers from 105 laboratories across seven countries announces a groundbreaking research paper submitted to eLife.

26 Mar 2024

DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

Researchers from North Carolina State University have developed a new generation of high-performance DNA aptamers and highly accurate drug sensors for cocaine and other opioids.

5 Mar 2024

Delta opioid receptor agonist reduces anxiety-like behavior in mice

Anxiety-related disorders can have a profound impact on the mental health and quality of life of affected individuals.

22 Feb 2024

Scientists discover how oxytocin influences memory in animals

Oxytocin (OXT) is a hormone that is known for its effects on psychological well-being and emotional bonding in animals.

13 Feb 2024

Cannabis and alcohol co-use disrupts brain development and impairs memory

The increased legalization of cannabis over the past several years can potentially increase its co-use with alcohol. Concerningly, very few studies have looked at the effects of these two drugs when used in combination.

30 Nov 2023

Researchers develop innovative treatment option for therapy-resistant epilepsy

Neuroscientist Professor Sonja Bröer from Freie Universität Berlin is involved in the development of an innovative treatment option for therapy-resistant epilepsy.

6 Oct 2023

Experimental insomnia treatment may help prevent opioid relapse

A good night's sleep has many proven health benefits, and a new Scripps Research study suggests one more: preventing opioid relapse.

6 Sep 2023

Binge drinking during adolescence leads to long-lasting brain changes, research suggests

Heavy alcohol consumption may cause permanent dysregulation of neurons, or brain cells, in adolescents, according to a new study in mice.

9 Jun 2023

First-in-class drug shows promise as a safe and effective treatment for cannabis use disorder

A first-in-class drug engineered to selectively inhibit the signaling pathway of the cannabinoid receptor shows promise as a safe and effective treatment for cannabis use disorder (CUD), a condition where a person is unable to control their cannabis use, even though it's causing problems in their lives.

8 Jun 2023

Study shows the power of gamma enhancement as potential approach for countering depression

Led by researchers from NYU Grossman School of Medicine and Hungary's University of Szeged, a new study in mice and rats found that restoring certain signals in a brain region that processes smells countered depression.

9 May 2023

VR imaging system illuminates functional brain network dynamics in autism model

An international research collaboration has developed a VR imaging system that can measure a wide range of neural activity in the cortices of mice during active behavior.

28 Mar 2023

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

In a recent study published in the journal Neuropharmacology, researchers in Pisa, Italy, explored how gut microbiota can influence neuroplasticity.

20 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Water enriched with hydrogen molecules improves symptomatology of neuropathic pain in animal models

In an article published in the journal Antioxidants, researchers from the Hospital de la Santa Creu i Sant Pau Research Institute (IIB Sant Pau) and the Universitat Autònoma de Barcelona demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances.

13 Dec 2022

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. Regarding juvenile Parkinson, which represents the of all Parkison's cases, the disease begins before 40 years old.

8 Nov 2022

Researchers discover neuronal mechanism involved in the learning of maternal behavior

Various conditions such as postpartum depression or postpartum psychosis can lead to an alteration in maternal behavior and disrupt the mother-child bonding process.

8 Nov 2022

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Alzheimer's disease (AD), characterized by an accumulation of β-amyloid protein (Aβ) in brain tissue, is a leading cause of dementia.

24 Oct 2022

Chemical compounds in coffee beans may help lighten the effects of morning nicotine cravings

For some smokers, the first cigarette of the day is just not as satisfying without a cup of coffee. That could be more than just a morning habit: Chemical compounds in roasted coffee beans may help lighten the effects of morning nicotine cravings, University of Florida researchers have found.

17 Aug 2022

Gait analysis in animals: Treadmill versus non treadmill system

This interview will look into talking about different systems used for analyzing gait in animals, in treadmill versus non-treadmill systems.

From Noldus Information Technology 8 Aug 2022

IU researchers evaluate the efficacy of a failed clinical trial drug for Alzheimer's using rigorous pipeline

Most drugs developed to treat Alzheimer's disease have for years been ineffective in clinical trials. Researchers from Indiana University School of Medicine recently evaluated the efficacy of a failed clinical trial drug using their rigorous pipeline.

25 Jul 2022