Neuropharmacology News and Research

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Investigating how gut microbiota affect neuroplasticity and neurodevelopment

In a recent study published in the journal Neuropharmacology, researchers in Pisa, Italy, explored how gut microbiota can influence neuroplasticity.

20 Mar 2023

Discovery could lead to effective treatments for acute alcohol intoxication

A shot of a liver-produced hormone called FGF21 sobered up mice that had passed out from alcohol, allowing them to regain consciousness and coordination much faster than those that didn't receive this treatment, UT Southwestern researchers report in a new study.

8 Mar 2023

Water enriched with hydrogen molecules improves symptomatology of neuropathic pain in animal models

In an article published in the journal Antioxidants, researchers from the Hospital de la Santa Creu i Sant Pau Research Institute (IIB Sant Pau) and the Universitat Autònoma de Barcelona demonstrate in animal models that water enriched with hydrogen molecules (H2) improves the symptomatology of neuropathic pain and related emotional disturbances.

13 Dec 2022

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Parkinson's disease affects 3% of population over 65 years old, and the average age of onset is 60. Regarding juvenile Parkinson, which represents the of all Parkison's cases, the disease begins before 40 years old.

8 Nov 2022

Researchers discover neuronal mechanism involved in the learning of maternal behavior

Various conditions such as postpartum depression or postpartum psychosis can lead to an alteration in maternal behavior and disrupt the mother-child bonding process.

8 Nov 2022

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Alzheimer's disease (AD), characterized by an accumulation of β-amyloid protein (Aβ) in brain tissue, is a leading cause of dementia.

24 Oct 2022

Chemical compounds in coffee beans may help lighten the effects of morning nicotine cravings

For some smokers, the first cigarette of the day is just not as satisfying without a cup of coffee. That could be more than just a morning habit: Chemical compounds in roasted coffee beans may help lighten the effects of morning nicotine cravings, University of Florida researchers have found.

17 Aug 2022

Gait analysis in animals: Treadmill versus non treadmill system

This interview will look into talking about different systems used for analyzing gait in animals, in treadmill versus non-treadmill systems.

From Noldus Information Technology 8 Aug 2022

IU researchers evaluate the efficacy of a failed clinical trial drug for Alzheimer's using rigorous pipeline

Most drugs developed to treat Alzheimer's disease have for years been ineffective in clinical trials. Researchers from Indiana University School of Medicine recently evaluated the efficacy of a failed clinical trial drug using their rigorous pipeline.

25 Jul 2022

Oligomeric molecular structure of the MOR-Gal1R complex revealed

A study published in the journal Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids.

22 Jul 2022

What does the Future Look Like for Patient Centricity within Clinical Trials?

In this interview, we speak to Dr. Paresh Malhotra about what the future holds for patient centricity within clinical trials, and the benefits for this focus.

7 Mar 2022

Researchers study how brain deficits associated with HIV and cocaine addiction might add up

Researchers with the Del Monte Institute for Neuroscience at the University of Rochester are studying how the brain puts the 'brakes' on behavior. That may be different in individuals recovering from cocaine addiction and who are also HIV-positive.

21 Dec 2021

UTSW study points to a new way to fight parasitic nematode diseases

Combining two agents to block a parasitic worm's life cycle boosted survival from a potentially deadly tropical disease to 85% in animal models, far better than either treatment alone, according to a proof-of-concept study led by UT Southwestern Medical Center pharmacologists.

11 Dec 2021

Clinical drug research for the treatment of CNS and neurological disorders

Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders.

29 Nov 2021

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Mark Bear, Picower Professor of Neuroscience at MIT, recalls the "eureka moment" 20 years ago when he realized that a severe developmental brain disorder -;fragile X syndrome-;might be treated with drugs that inhibit a neurotransmitter receptor called mGluR5.

29 Sep 2021

Study reveals potential therapeutic target to tackle ADHD and impulsivity

A study published in the journal Pharmacological Research describes the existence of a complex built by dopamine and noradrenergic receptors that could be a therapeutic target of potential interest to tackle the attention deficit hyperactivity disorder (ADHD) and impulsivity.

23 Sep 2021

Neuropharmacology News and Research

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

Discovery could lead to effective treatments for acute alcohol intoxication

Water enriched with hydrogen molecules improves symptomatology of neuropathic pain in animal models

Researchers decipher key mechanism in the pathogenesis of juvenile Parkinson's

Researchers discover neuronal mechanism involved in the learning of maternal behavior

Novel oxytocin derivative can reverse Aβ25-35-induced cognitive impairment in mice

Chemical compounds in coffee beans may help lighten the effects of morning nicotine cravings

Gait analysis in animals: Treadmill versus non treadmill system

IU researchers evaluate the efficacy of a failed clinical trial drug for Alzheimer's using rigorous pipeline

Oligomeric molecular structure of the MOR-Gal1R complex revealed

What does the Future Look Like for Patient Centricity within Clinical Trials?

Researchers study how brain deficits associated with HIV and cocaine addiction might add up

UTSW study points to a new way to fight parasitic nematode diseases

Clinical drug research for the treatment of CNS and neurological disorders

Research points to new opportunities to prevent treatment resistance in fragile X syndrome

Study reveals potential therapeutic target to tackle ADHD and impulsivity

Long-term circadian rhythm disruption induces Alzheimer's-like pathology in rats

New technique identifies specific neural pathways involved in executive functions of the brain

Reconstituted mRNA Covid-19 vaccines can be safely transported

UCLA clinical trial shows efficacy of varenicline on heavy-drinking smokers

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Realizing the Importance of Medical Electronic Devices

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