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Study identifies new genetic variant associated with ARDS

An international study in which Javier Belda, Professor of Surgery at the University of Valencia and Incliva researcher, participated, has identified a new genetic variant associated with Acute Respiratory Distress Syndrome.

28 Jan 2019

Researchers discover how cancer cells avoid genetic meltdown

A team of scientists have shed light on how cancer cell populations avoid genetic meltdown, despite the rapid accumulation of harmful mutations.

15 Jan 2019

Novel technique detects new strains of microbes in human fecal microbiota after obesity surgery

Using a unique bioinformatics technique developed at the University of Alabama at Birmingham, UAB researchers have detected the emergence of new strains of microbes in the human fecal microbiota after obesity surgery.

9 Jan 2019

PAC1R mutation in children with autism may be linked to severity of social problems

A mutation of the gene PAC1R may be linked to the severity of social deficits experienced by kids with autism spectrum disorder, finds a study from a multi-institutional research team led by Children's faculty.

8 Jan 2019

Nature-based antibiotic molecules for treatment of infections

New developments in antimicrobial peptides (AMPs) with antibiofilm properties are rapidly materializing.

2 Jan 2019

Multi-database electronic research finds link between gene polymorphisms with zinc status

Zinc is one of the essential components in the diet of all living organisms. It is the second most abundant biological trace element after iron.

28 Dec 2018

Targeting thymidylate biosynthesis in kinetoplastid and apicomplexan protozoans

Kinetoplastid and apicomplexan parasites include protozoans which are responsible for human diseases, and cause a serious impact on human health and the socioeconomic growth of developing countries. Chemotherapy is the main option to control these pathogenic organisms.

27 Dec 2018

Genetic marker, predictor of early relapse in common childhood cancer discovered

Nova Southeastern University researchers recently discovered that by testing the level of NER (nucleotide excision repair) gene expression, pediatric oncologists can determine the likelihood of early relapse (less than three years) in their acute lymphoblastic leukemia patients.

14 Dec 2018

Researchers create new approach to classify patients with Alzheimer's disease

Researchers studying Alzheimer's disease have created an approach to classify patients with Alzheimer's disease, a finding that may open the door for personalized treatments.

5 Dec 2018

New York State approves NYGC's Whole Genome and Transcriptome Sequencing for oncology

The New York Genome Center has received approval from the New York State Department of Health to offer whole genome and RNA transcriptome sequencing in its Clinical Laboratory Evaluation Program-certified laboratory.

29 Nov 2018

Discovery could be used to prevent viral infection and autoimmunity

Researchers have discovered that chemical changes to mRNA regulate the production of interferon beta, and hope to exploit this in new treatments.

27 Nov 2018

Research may pave way for development of potent weapons against cancer

Despite significant advances in cancer research, the disease continues to exact a devastating toll. Because cancer is a disease of the body's own cells, which mutate and develop under evolutionary pressure, conventional treatments like chemotherapy and radiation often leave behind a residue of resistant cells that go on to expand and wreak havoc.

27 Nov 2018

International study of ADHD at genomic scale

An international study, focused on the analysis of the genome of more than 50,000 people worldwide, has identified twelve specific fragments of DNA related to the vulnerability of the attention deficit hyperactivity disorder.

26 Nov 2018

New method enhances efficiency and accuracy of single cell RNA sequencing

In the era of personalized medicine, scientists are using new genetic and genomic insights to help them determine the best treatment for a given patient. In the case of cancer, the first step toward these treatments is an investigation into how tumor cells behave in an effort to figure out the best drugs to use to attack them.

22 Nov 2018

About 300 million bits of DNA are missing from basic reference genome, report scientists

For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of "baseline" reference and human species representation for comparing genetic variety among groups of people.

20 Nov 2018

Non-coding genetic variant plays key role in endothelial function and disease incidence

Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 people in the United States.

15 Nov 2018

Speed and error rate of DNA synthesis influenced by DNA structure

The speed and error rate of DNA synthesis is influenced by the three-dimensional structure of the DNA. Using "third-generation" genome-wide DNA sequencing data, a team of researchers from Penn State and the Czech Academy of Sciences showed that sequences with the potential to form unusual DNA conformations, which are frequently associated with cancer and neurological diseases, can in fact slow down or speed up the DNA synthesis process and cause more or fewer sequencing errors.

14 Nov 2018