Oligonucleotides News and Research

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Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. Automated synthesizers allow the synthesis of oligonucleotides up to 160 to 200 bases.
Awards for contributions to analytical chemistry and applied spectroscopy announced by Pittcon

Awards for contributions to analytical chemistry and applied spectroscopy announced by Pittcon

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

CRISPR-Gold corrects gene mutations in mice with Duchenne muscular dystrophy

DNA sensor systems provide highly sensitive monitoring of cancer-related enzyme activity

DNA sensor systems provide highly sensitive monitoring of cancer-related enzyme activity

Genevac’s new web page illustrates advantages of evaporative sample preparation for mass spectrometry

Genevac’s new web page illustrates advantages of evaporative sample preparation for mass spectrometry

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Positive CHMP opinion recognizes efficacy of Biogen’s SPINRAZA for treatment of spinal muscular atrophy

Targeted treatment slows progression of two degenerative brain diseases in mice

Targeted treatment slows progression of two degenerative brain diseases in mice

Using spherical nucleic acids to track and treat disease

Using spherical nucleic acids to track and treat disease

MIT researchers develop new machine to rapidly produce customized peptides

MIT researchers develop new machine to rapidly produce customized peptides

Designer compound may be effective tool for tackling tau-related disorders

Designer compound may be effective tool for tackling tau-related disorders

Research unravels molecular mechanisms of antisense oligonucleotides

Research unravels molecular mechanisms of antisense oligonucleotides

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

CSHL researcher-inventor hails FDA approval of new SMA drug

CSHL researcher-inventor hails FDA approval of new SMA drug

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Ionis announces FDA approval of first SMA drug in the U.S for pediatric and adult patients

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

Turning off 'fat-specific protein 27' improves blood sugar levels, reduces body fat in animal model

Study offers promise for therapeutic management of fetal and congenital genetic diseases in utero

Study offers promise for therapeutic management of fetal and congenital genetic diseases in utero

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

Scientists find way to boost efficiency with which CRISPR-Cas9 cuts and disables genes

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Overcoming gene silencing barriers to target neurological conditions: an interview with Dr Errol de Souza

Novel conjugate therapy shows promise in destroying ALL cells with few side effects

Novel conjugate therapy shows promise in destroying ALL cells with few side effects

Promising new therapeutic target could lead to better prognosis of spinal muscular atrophy

Promising new therapeutic target could lead to better prognosis of spinal muscular atrophy

Duke to lead early-stage clinical trials for promising new neurological therapies

Duke to lead early-stage clinical trials for promising new neurological therapies