Oligonucleotides News and Research

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Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. Automated synthesizers allow the synthesis of oligonucleotides up to 160 to 200 bases.
Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Single-patient pilot study shows the ability of antisense oligonucleotide to suppress mutant ALS gene

Exploring the impact of DNA nanoswitches in RNA purification

Exploring the impact of DNA nanoswitches in RNA purification

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

Telomeric DNA damage response may increase susceptibility of elderly people to COVID-19

Study involving a rat model offers potential treatment for Alexander disease

Study involving a rat model offers potential treatment for Alexander disease

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

Nucleoside modifications suppress the potential of RNA to activate dendritic cells

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

Plasmonic sensing of isothermally amplified nucleic acids and single-molecule detection of SARS-CoV-2

Design of mRNA vaccines to combat COVID-19

Design of mRNA vaccines to combat COVID-19

The role of nanomaterials during the COVID-19 pandemic

The role of nanomaterials during the COVID-19 pandemic

Aptamers for Targeting SARS-CoV-2 Proteins

Aptamers for Targeting SARS-CoV-2 Proteins

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

Researchers find a way to turn SARS-CoV-2’s virulence mechanism against itself

Antisense oligonucleotides engineered to inhibit SARS-CoV-2

Antisense oligonucleotides engineered to inhibit SARS-CoV-2

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Innovative therapeutic platform for blood-to-brain delivery of antisense oligonucleotide therapy

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

Potential new treatment for mast cell cancers reduces tumor size and prevents organ infiltration

Diagnosis of viral infections using micro and nanoscale technologies

Diagnosis of viral infections using micro and nanoscale technologies

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

Researchers discover titanium oxide nanoparticle that recognizes SARS-CoV-2’s non-structural protein 1

Polyuridine sequence of mouse coronavirus can be targeted to prevent host cell death

Polyuridine sequence of mouse coronavirus can be targeted to prevent host cell death

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

Could novel biosensors facilitate SARS-CoV-2 antiviral drug research?

SARS-CoV-2 interacts with unusual RNA structures in human cells

SARS-CoV-2 interacts with unusual RNA structures in human cells

Neutralizing aptamers block SARS-CoV-2 infection in vitro

Neutralizing aptamers block SARS-CoV-2 infection in vitro

Uncovering cellular mechanism related to gene silencing therapies

Uncovering cellular mechanism related to gene silencing therapies