Oligonucleotides News and Research

RSS
Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. Automated synthesizers allow the synthesis of oligonucleotides up to 160 to 200 bases.
How and when do de novo SARS-CoV-2 spike mutations emerge?

How and when do de novo SARS-CoV-2 spike mutations emerge?

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

Scientists explore guanine-specific pocket in SARS-CoV-2 nucleocapsid protein of therapeutic value against multiple coronaviruses

DNA may act as nutritional source for E. coli

DNA may act as nutritional source for E. coli

Novel nanoligomer approach to treat severe COVID-19

Novel nanoligomer approach to treat severe COVID-19

First open-source program can improve detection and tracking of pathogenic DNA sequences

First open-source program can improve detection and tracking of pathogenic DNA sequences

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

New model rapidly scans the genome of cancer cells and identifies mutations that drive tumor growth

Interactive web portal details the extent of splicing events in noncoding sequences

Interactive web portal details the extent of splicing events in noncoding sequences

The promise of RNA medicine is targeted and personalized

The promise of RNA medicine is targeted and personalized

New initiative focuses on patients with the rarest of gene mutations to develop personalized ALS therapies

New initiative focuses on patients with the rarest of gene mutations to develop personalized ALS therapies

New insights could lead to better treatments for Dravet syndrome and related conditions

New insights could lead to better treatments for Dravet syndrome and related conditions

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

Potential diagnostic method for identifying human health-relevant nucleic acids utilizing FokI-assisted digestion of DNA duplexes and DNA/RNA hybrids

RNA interference triggers that target SARS-CoV-2 genome

RNA interference triggers that target SARS-CoV-2 genome

Scientists create a biobank of 87 triple-negative breast cancer organoids

Scientists create a biobank of 87 triple-negative breast cancer organoids

A summary of SARS-CoV-2 RNA-protein interactome studies

A summary of SARS-CoV-2 RNA-protein interactome studies

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

CASCADE biosensor found to be effective in naked-eye SARS-CoV-2 RNA detection

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

Study evaluates colorimetric sensors for SARS-CoV-2 detection using gold nanoparticles

Assessment of oligonucleotides as COVID-19 treatment

Assessment of oligonucleotides as COVID-19 treatment

Current and future perspectives of mRNA technology

Current and future perspectives of mRNA technology

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Codiak's publication highlights the ability of exoASO-STAT6 to selectively target tumor-associated macrophages

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread

Researchers find a way to interfere with the energy pathway that promotes liver cancer spread