Oligonucleotides News and Research

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Oligonucleotides are short sequences of nucleotides (RNA or DNA), typically with twenty or fewer bases. Automated synthesizers allow the synthesis of oligonucleotides up to 160 to 200 bases.
Inhibition of SARS-CoV-2 with antisense oligonucleotides

Inhibition of SARS-CoV-2 with antisense oligonucleotides

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

Serum protein shows therapeutic value against severe COVID-19-like features in mouse model

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

RNA-based therapeutic approach holds promise as potential cure for hereditary diseases

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

FDA approves new treatment option for patients with rare Duchenne muscular dystrophy mutation

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

Large-scale analysis of Alport syndrome reveals the effectiveness of existing treatments

Picomolar inhibitors to SARS-CoV-2 proteins

Picomolar inhibitors to SARS-CoV-2 proteins

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Researchers develop new therapeutic approach to treat CLN3 Batten disease

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Study: L-Grb2 has therapeutic efficacy in preclinical models of ovarian and uterine cancer

Experimental drug for rare ALS shows promise in early clinical trial

Experimental drug for rare ALS shows promise in early clinical trial

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

Researchers develop a potential treatment approach for Pelizaeus-Merzbacher disease

Researchers develop a potential treatment approach for Pelizaeus-Merzbacher disease

Researchers develop potential new therapy for common form of muscular dystrophy

Researchers develop potential new therapy for common form of muscular dystrophy

New therapeutic approach for Parkinson’s and other neurodegenerative diseases

New therapeutic approach for Parkinson’s and other neurodegenerative diseases

Tumor cell–based vaccine may prevent relapse of mantle cell lymphoma

Tumor cell–based vaccine may prevent relapse of mantle cell lymphoma

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

Mapping RNA sequences of therapeutic value in the SARS-CoV-2 genome

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

AFFiRiS announces preclinical results of monoclonal antibody mAB C6-17 in Huntington's

IDT opens new manufacturing facility to expand capacity of COVID-19 products

IDT opens new manufacturing facility to expand capacity of COVID-19 products

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Scientists gain new insight into the pathological mechanisms behind two neurodegenerative diseases

Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

Horizon Discovery and Pharmahungary report positive early-stage results for novel micro-RNA therapeutic for ischemic heart diseases

New partnership aims to explore, cultivate innovations in cell and gene therapy

New partnership aims to explore, cultivate innovations in cell and gene therapy