Oral Cancer News and Research

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Oral cancer is the sixth most common type of cancer worldwide and in the U.S., one person dies every hour from the disease. According to American Cancer Society data, nearly as many women will be diagnosed with oral cancer as with cervical cancer this year. The key to reducing the impact of this disease is early detection.

Researchers find mechanism that explains differences in skin’s responsiveness to heat, mechanical stimuli

Researchers at the Bluestone Center for Clinical Research at the New York University College of Dentistry (NYU Dentistry) have identified a novel molecular mechanism which explains why dark-skinned and light-skinned people respond differently to heat and mechanical stimulation.

6 Sep 2017

Research paves way for new drugs that may prevent tumor repopulation after radiation therapy

Whenever an organism is damaged, the cells surrounding the wound receive signals to proliferate more intensely so as to regenerate the injured tissue.

26 Aug 2017

NYU researcher to study biological differences between men and women in oral cancer pain

Nicole Scheff, PhD, a postdoctoral fellow in the laboratory of Dr. Brian L. Schmidt, director of the NYU Bluestone Center for Clinical Research and the NYU Oral Cancer Center, both located at New York University College of Dentistry, has received a two-year, $120,000-plus F32 grant from the National Institute of Dental and Craniofacial Research.

10 Jul 2017

Cells key to blood vessel formation can also produce tumors and enable their spread

While it's widely held that tumors can produce blood vessels to support their growth, scientists now have evidence that cells key to blood vessel formation can also produce tumors and enable their spread.

20 Jun 2017

Case Western Reserve University researchers aim to treat oral complications of HIV

While advances in HIV treatment have dramatically improved patient lifespans and quality of life, nagging side effects remain; among the most common is chronic inflammation--essentially, when an immune system imbalance causes the body to attack itself.

6 Apr 2017

UNMC seeking patients with lymphoma to evaluate two-drug oral therapy

The University of Nebraska Medical Center is seeking 24 patients to enroll in a Phase 2a study to evaluate the safety and efficacy of two oral cancer drugs for patients with diffuse large B-cell lymphoma who have relapsed or are resistant to other traditional therapies.

9 Dec 2016

Study shows involvement of lipid metabolism in tumour metastasis

A study headed by Salvador Aznar Benitah, ICREA researcher at the Institute for Research in Biomedicine, and published today in Nature identifies metastasis-initiating cells through a specific marker, namely the protein CD36.

7 Dec 2016

Mouth cancer rates increase by 68% in the UK over last two decades

A NEW Cancer Research UK analysis reveals that rates of mouth (oral) cancer have jumped by 68 per cent in the UK over the last 20 years, today (Friday).

24 Nov 2016

University of Warwick to conduct research in Pakistan for better diagnosis, treatment of oral cancer

One of the deadliest and most prevalent cancers in the Indo-Pakistan region could be treated more effectively, thanks to a new research project being undertaken at the University of Warwick, in collaboration with University Hospitals Coventry and Warwickshire NHS Trust and the Shaukat Khanum Memorial Cancer Hospital & Research Centre in Pakistan.

6 Oct 2016

Study highlights impact of cognitive functions on oral cancer treatment

The development of oral cancer drugs as a modality therapy over the last decade has highlighted the problem of non-adherence. Only cancer drugs that are taken can actually work.

4 Oct 2016

NYU dentists receive grant to test whether non-viral gene delivery can effectively treat oral cancer pain

The National Institute of Dental and Craniofacial Research, part of the National Institutes of Health, has awarded Drs. Brian Schmidt and Seiichi Yamano a $1.2M (3-year) grant to test whether their non-viral gene delivery method can effectively and safely treat oral cancer pain.

28 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

Scientists discover reliable marker to spot CAFs in oral cancer tissues

For the first time, researchers have identified a reliable marker (PDGFRβ) to detect carcinoma-associated fibroblasts (cells within the tumor that encourage growth and metastasis) (CAFs) in oral cancer tissues. With this discovery, anti-PDGFRβ treatment could soon be combined with existing tumor treatments to provide a more effective cancer therapy.

11 May 2016

New oral cancer drugs getting more expensive over time, study shows

New cancer drugs taken in pill form have become dramatically more expensive in their first year on the market compared with drugs launched 15 years ago, a University of North Carolina at Chapel Hill study has found. The findings call into question the sustainability of a system that sets high prices at market entry in addition to rapidly increasing those prices over time.

30 Apr 2016

Study sheds light on role of RNA editing in cancer

A new study provides insight on the potential role played by RNA (ribonucleic acid) editing in cancer. The findings, which appear online in the journal Scientific Reports, may further our understanding of an emerging mechanism implicated in tumor initiation and progression, and may thus lead to the development of better treatment options in the future.

18 Mar 2016

Molecular basis for tongue cancer progression: an interview with Dr Simona Principe

Head and neck cancers (HNC) are the sixth most common cancers worldwide, with approximately 600,000 new cases diagnosed every year.

From Beckman Coulter Life Sciences - Centrifugation 17 Mar 2016

This No Smoking Day think of your oral health and kick the habit

Europe’s largest dental treatment provider, mydentist, is calling on smokers across the UK to quit on No Smoking Day for the good of their oral health.

24 Feb 2016

Scientists identify potential marker for recurring HPV-positive oropharyngeal cancer

A look-back analysis of HPV infection antibodies in patients treated for oropharyngeal (mouth and throat) cancers linked to HPV infection suggests at least one of the antibodies could be useful in identifying those at risk for a recurrence of the cancer, say scientists at The Johns Hopkins University.

7 Feb 2016

Researchers partner to help personalize cancer care

Researchers at the University of Iowa College of Dentistry are partnering with a private company to develop computer simulations that can help personalize cancer care by predicting how a patient will respond to a drug treatment.

7 Dec 2015

New tool could help identify patients most likely to benefit from chemoprevention

A team of scientists, led by researchers at University of California, San Diego Moores Cancer Center and The University of Texas MD Anderson Cancer Center, report that a genetic biomarker called loss of heterozygosity or LOH is able to predict which patients with premalignant mouth lesions are at highest risk of developing oral cancer.

6 Nov 2015