Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

In a first for USC Stem Cell scientists, the laboratory of Giorgia Quadrato, an assistant professor of stem cell biology and regenerative medicine, has pioneered a novel human brain organoid model that generates all the major cell types of the cerebellum, a hindbrain region predominantly made up of two cell types necessary for movement, cognition, and emotion: granule cells and Purkinje neurons.

4 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

Imbalances in folic acid and vitamin B12 can alter brain development in mice

Folate is a B vitamin and a necessary nutrient to prevent neural tube defects, such as spina bifida. Folic acid, a synthetic form of folate, has been added to vitamins, breakfast cereals and other products in the U.S. and more than 80 other countries to ensure pregnant women get adequate amounts.

4 Jan 2024

How immune cells shape our earliest breaths

Study profiles the development of immune cells in human lungs during embryonic and fetal stages, revealing their influence on epithelial cell fate and lung development.

1 Jan 2024

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

26 Dec 2023

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Non-human primates (NHPs) have a high degree of similarity to humans compared to other animal models.

22 Dec 2023

Study reveals how measles virus mutates and spreads in the human brain

Mayo Clinic researchers mapped how the measles virus mutated and spread in the brain of a person who succumbed to a rare, lethal brain disease.

21 Dec 2023

UW-Madison technology unveils autism gene's impact on early brain structure

Technology developed at the University of Wisconsin–Madison to grow "rosettes" of brain and spinal tissue gives scientists new ways to study the growing human brain, including a recent study of how genetic mutations linked to autism affect early stages of human brain development.

20 Dec 2023

Patient-specific muscle models pave way for personalized neuromuscular therapies

Scientists have so far identified around 800 different neuromuscular diseases. These conditions are caused by problems in the way muscle cells, motor neurons and peripheral cells interact.

19 Dec 2023

Exploring instruments for assay development and optimization

In this interview, Michael Nilsson, the Assistant Director of Liquid Handling at FORMULATRIX , talks to News Medical about simplifying assay development and optimization and the different instruments that can be used to minimize cost.

From FORMULATRIX 19 Dec 2023

Experts from leading institutions launch Pandemic Research Alliance for collaborative virus defense

World-renowned professors from six leading institutions in four countries launched the Pandemic Research Alliance (PRA) today (4 December) to drive concerted research into respiratory viruses from animals to humans, improved surveillance, and new solutions to better manage the next pandemic.

17 Dec 2023

Waseda researchers unravel secrets of building better brain organoids with blood vessels

Researchers at Waseda University led by Assistant Professor Kosuke Kataoka, have uncovered crucial insights into brain organoids’ development.

15 Dec 2023

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

A new LMU-led DFG Research Unit is developing innovative approaches for treating retinal diseases.

15 Dec 2023

QUT scientists discover promising treatment for fatal endometrial cancer

QUT scientists have discovered a promising new therapy for a deadly type of endometrial cancer that has a poor prognosis if the cancer spreads or returns after initial treatment, a plight that affects 15-20 per cent of endometrial cancer patients.

15 Dec 2023

Researchers unveil new way to sensitize resistant tumors to treatment

Resistance to therapies is one of the obstacles to overcome in cancer treatments. Understanding the mechanisms of this resistance is essential to design strategies that favor tumor cell death.

14 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Brainoware: A breakthrough AI approach using brain organoids for advanced computation

Study in Nature Electronics introduces "Brainoware," an innovative AI hardware approach using brain organoid neural networks for complex tasks like speech recognition and nonlinear dynamic predictions, demonstrating significant potential in AI development.

12 Dec 2023

Organoids News and Research

Further Reading

USC scientists develop first all-human brain organoids model of the cerebellum with functional neurons

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

Imbalances in folic acid and vitamin B12 can alter brain development in mice

How immune cells shape our earliest breaths

New drug screening system helps uncover promising target for pancreatic cancer treatments

Monkey stem cells made easy: New method unveils xeno-free, efficient culture system

Study reveals how measles virus mutates and spreads in the human brain

UW-Madison technology unveils autism gene's impact on early brain structure

Patient-specific muscle models pave way for personalized neuromuscular therapies

Exploring instruments for assay development and optimization

Experts from leading institutions launch Pandemic Research Alliance for collaborative virus defense

Waseda researchers unravel secrets of building better brain organoids with blood vessels

New LMU-led DFG Research Unit eyes innovative gene therapies for retinal diseases

QUT scientists discover promising treatment for fatal endometrial cancer

Researchers unveil new way to sensitize resistant tumors to treatment

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Brainoware: A breakthrough AI approach using brain organoids for advanced computation

New organoid model could revolutionize neuroendocrine tumor research

Breakthrough in pancreatic cancer treatment: Inhibiting specific enzymes slows tumor progression

Fused pancreatic cancer organoid system captures tumor heterogeneity and drug resistance

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

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