Organoids News and Research

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Organoids are three-dimensional cell cultures from embryonic stem cells or induced pluripotent stem cells that model important features of whole organs.

INTEGRA Biosciences' vacuum aspiration systems help researchers solve the dog epigenome

Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative.

From INTEGRA Biosciences 30 Aug 2023

New kidney tissue model could help assess safety of immunotherapy drugs

A growing repertoire of cell and molecule-based immunotherapies is offering patients with indomitable cancers new hope by mobilizing their immune systems against tumor cells.

23 Aug 2023

Mitochondrial dysfunction may be a contributor to schizophrenia

Researchers at Rutgers and Emory University are gaining insights into how schizophrenia develops by studying the strongest-known genetic risk factor.

16 Aug 2023

Stem cells used to create organoids that secrete dental enamel proteins

Organoids have now been created from stem cells to secrete the proteins that form dental enamel, the substance that protects teeth from damage and decay.

14 Aug 2023

Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Scientists have developed a synthetic extracellular matrix (ECM) that can support the growth of a mini endometrium in a dish for at least two weeks.

11 Aug 2023

Brain development linked to the emergence of autism spectrum disorder

Two distinct neurodevelopmental abnormalities that arise just weeks after the start of brain development have been associated with the emergence of autism spectrum disorder, according to a new Yale-led study in which researchers developed brain organoids from the stem cells of boys diagnosed with the disorder.

10 Aug 2023

New gene-editing tool helps to study single-base mutations in cancer

A change in just one letter in the code that makes up a cancer-causing gene can significantly affect how aggressive a tumor is or how well a patient with cancer responds to a particular therapy.

10 Aug 2023

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

A new study of mice and lab-grown human colon "organoids" indicates that an experimental drug developed by Johns Hopkins Medicine researchers can substantially reduce symptoms of inflammatory bowel disease (IBD) in pre-clinical models.

10 Aug 2023

Autism spectrum disorder may be linked to imbalance of neurons in the brain

Using human "mini-brain" models known as organoids, Mayo Clinic and Yale University scientists have discovered that the roots of autism spectrum disorder may be associated with an imbalance of specific neurons that play a critical role in how the brain communicates and functions.

10 Aug 2023

New mechanism discovered for coordinating organ development

Researchers at the Instituto Gulbenkian de Ciência (IGC, Oeiras) and Max Planck Institute of Cell Biology and Genetics (MPI-CBG, Dresden) identified a new mechanism that exposes some of the multitasking abilities embryos need to build a functional retina, the sensory part of the central nervous system responsible for vision.

9 Aug 2023

What are some recent advancements in proteomics-driven pancreatic oncology research?

The application of proteomics-driven biomarkers for early detection, diagnosis, and treatment of pancreatic cancer.

9 Aug 2023

NLRP3 inflammasome plays a role in podocyte aging

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 14, entitled, "Inhibiting NLRP3 signaling in aging podocytes improves their life- and health-span."

8 Aug 2023

Cancer's silent progression: research delves into evolutionary clues in breast cancer

Researchers performed phylogenetic analyses to trace the evolution of breast cancer and precursor lesions.

2 Aug 2023

AirGels: A game-changer for research on respiratory infections

Biofilms are highly resistant communities of bacteria that pose a major challenge in the treatment of infections.

1 Aug 2023

MU researchers receive $3 million grant to study preeclampsia

University of Missouri researchers are striving to find solutions to the leading cause of maternal mortality in the world -; preeclampsia. For Laura Schulz, an associate professor of obstetrics, gynecology and women's health in the University of Missouri School of Medicine, understanding the root causes of preeclampsia and other complicated, life-threatening maternal conditions is pivotal in advancing women's health care.

27 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

Study identified pathogenic variants in the EZH1 as a cause of neurodevelopmental disorders.

14 Jul 2023

U-M researchers develop animal-free method to produce brain organoids

Researchers at University of Michigan developed a method to produce artificially grown miniature brains -; called human brain organoids -; free of animal cells that could greatly improve the way neurodegenerative conditions are studied and, eventually, treated.

13 Jul 2023

LIONESS: A new tool for unraveling mysteries of the brain

Brain tissue is one of the most intricate specimens that scientists have arguably ever dealt with. Packed with currently immeasurable amount of information, the human brain is the most sophisticated computational device with its network of around 86 billion neurons.

10 Jul 2023

Study traces the natural evolution of earliest stages of human cancers

Cancer cells-to-be accumulate a series of specific genetic changes in a predictable and sequential way years before they are identifiable as pre-malignancies, researchers at Stanford Medicine have found.

7 Jul 2023

Organoids News and Research

Further Reading

INTEGRA Biosciences' vacuum aspiration systems help researchers solve the dog epigenome

New kidney tissue model could help assess safety of immunotherapy drugs

Mitochondrial dysfunction may be a contributor to schizophrenia

Stem cells used to create organoids that secrete dental enamel proteins

Scientists develop synthetic extracellular matrix to support growth of mini endometrium in a dish

Brain development linked to the emergence of autism spectrum disorder

New gene-editing tool helps to study single-base mutations in cancer

Experimental drug can reduce symptoms of inflammatory bowel disease in pre-clinical models

Autism spectrum disorder may be linked to imbalance of neurons in the brain

New mechanism discovered for coordinating organ development

What are some recent advancements in proteomics-driven pancreatic oncology research?

NLRP3 inflammasome plays a role in podocyte aging

Cancer's silent progression: research delves into evolutionary clues in breast cancer

AirGels: A game-changer for research on respiratory infections

MU researchers receive $3 million grant to study preeclampsia

Aerobic glycolysis essential for eye development in mammals, study finds

Study uncovers pathogenic variants in the chromatin modifier EZH1 as the cause of neurodevelopmental disorders

U-M researchers develop animal-free method to produce brain organoids

LIONESS: A new tool for unraveling mysteries of the brain

Study traces the natural evolution of earliest stages of human cancers

One Health, One Mission: The World Organisation for Animal Health on the AMR Frontline

Uniting Against Resistance: The World Health Organization for World Antimicrobial Awareness Week 2023

Tackling Antimicrobial Resistance: A Conversation with Dr. Beverley Isherwood

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