Oropharyngeal Cancer News and Research

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Is obesity associated with risk of head and neck cancer?

The association between obesity and head and neck cancer risk.

29 Aug 2023

Study examines the link between oropharyngeal cancer and high-risk sexual behavior

The development of head and neck cancer is increasingly linked to HPV infection, which is a sexually transmitted disease.

14 Jul 2023

Experts emphasize the need to understand the strengths and limitations of ctHPV DNA testing

Oropharynx cancers caused by human papillomavirus (HPV) have risen dramatically over the years, superseding tobacco use and heavy drinking as the primary driver of new cases. Fortunately, HPV-positive oropharynx cancers have an improved survival rate compared to other head and neck cancers, allowing for less intensive treatment options, especially if diagnosed at early stages.

1 Nov 2022

HPV-related cancers increase in U.S. counties with low-income, high smoking prevalence

A new paper in JNCI Cancer Spectrum, published by Oxford University Press, finds increases in both men and women for several HPV-related cancers in low-income counties or those with high smoking rates. Increases were slower in the highest-income US counties or those with low smoking rates.

3 Mar 2022

DNA biomarker test helps predict recurrence of HPV-driven oropharyngeal cancer after treatment

A large, multi-institutional study demonstrates that a blood test to detect circulating tumor DNA can accurately predict recurrence of HPV-driven oropharyngeal cancer following treatment.

25 Feb 2022

Study reveals rising oropharyngeal cancer incidence and mortality trends in all 50 states

Oropharyngeal cancer incidence among men is continuing to rise rapidly in nearly all 50 states and among women living in states in the Midwest and Southeast regions, according to a new study by investigators at The University of Texas Health Science Center at Houston School of Public Health in JAMA Otolaryngology-Head & Neck Surgery.

16 Dec 2021

Trial positions single-dose HPV vaccination as a high impact public health intervention

In the push to eliminate cervical cancer, researchers delivered hopeful news Nov. 17 at the 34th International Papillomavirus Conference in Toronto.

20 Nov 2021

JunD promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA

Oncotarget published "JunD accentuates arecoline-induced disruption of tight junctions and promotes epithelial-to-mesenchymal transition by association with NEAT1 lncRNA" which reported that the effects of low and high concentrations of arecoline on the stability of tight junctions and EMT induction were studied.

3 Sep 2021

HPV16 ctDNA assay predicts treatment response in metastatic head and neck cancer

Oncotarget published "Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma" which reported that despite the rising incidence of human papillomavirus related oropharyngeal squamous cell carcinoma, treatment of metastatic disease remains palliative.

2 Aug 2021

Same-day screening and health education program seeks to reduce disparities of preventable cancers

Evidence shows that early detection and treatment of cancer can significantly improve health outcomes, however women in Mississippi, particularly in underserved populations, experience the worst health outcomes for cervical, breast, and oropharyngeal cancer.

20 Jul 2021

U-M study finds low HPV vaccination rate among young adult men in the U.S.

The COVID-19 vaccine isn't having any trouble attracting suitors. But there's another, older model that's been mostly ignored by the young men of America: the HPV vaccine.

27 Apr 2021

Reduced-dose radiotherapy with cisplatin produces good outcomes for HPV-associated oropharyngeal cancer

A combination of reduced-dose radiotherapy using intensity-modulated radiotherapy (IMRT) combined with concurrent cisplatin met the threshold for disease control and quality of life compared to the standard of care for good-risk patients with HPV-associated oropharyngeal squamous cell carcinoma on the NRG Oncology clinical trial NRG-HN002.

29 Jan 2021

Study reveals connection between oral sex and oropharyngeal cancer

A wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated head and neck cancer that can be spread through this route, a new study led by researchers at the Johns Hopkins Kimmel Cancer Center suggests.

15 Jan 2021

Study: Oral sex can increase risk of HPV-related oropharyngeal cancer

Human papillomavirus (HPV) can infect the mouth and throat to cause cancers of the oropharynx. A new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, has found that having more than 10 prior oral sex partners was associated with a 4.3-times greater likelihood of having HPV-related oropharyngeal cancer.

11 Jan 2021

Robotic surgery for oropharyngeal cancer associated with improved health outcomes

Robotic surgery for patients with early stage, oropharyngeal squamous cell cancer is associated with improved health outcomes, including better long-term survival, according to a Cedars-Sinai study published Thursday in JAMA Oncology.

20 Aug 2020

Simple saliva test detects early throat cancer

A simple saliva test developed by QUT biomedical scientists has detected early throat cancer in a person who had no symptom and no clinical signs of cancer.

12 May 2020

New trial platform could help evaluate potential therapies for Parkinson’s disease

Despite 30 years of research, not a single therapy has been found to successfully delay or stop the progression of Parkinson's disease.

6 May 2020

Radiation therapy plays a crucial role in management of OPSCC

HPV-negative UM-SCC4 with and without transfection of HPV E6 oncoprotein, HPV-negative UPCI-SCC-089, and HPV-positive UPCI-SCC-099 cell lines were used in this study.

22 Apr 2020

Racial, socioeconomic disparities found among patients with HPV-positive oropharyngeal cancer

Survival outcomes for HPV-positive oropharyngeal squamous cell carcinoma of the head and neck have made significant gains in recent years, but new research in the February 2020 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds some groups are being left behind.

6 Feb 2020

New plant-based drug shown to help patients with head and neck cancers

In a UCLA-led phase I clinical trial, a new plant-based drug called APG-157 showed signs of helping patients fight oral and oropharyngeal cancers. These cancers are located in the head and the neck.

5 Feb 2020