Osteosarcoma News and Research

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Between two and three percent of all childhood cancers are osteosarcoma. Because osteosarcoma usually develops from osteoblasts, it most commonly affects children and young adults experiencing their adolescent growth spurt. Boys and girls have a similar incidence rate until later in their adolescence, when boys are more commonly affected. While most tumors occur in larger bones, such as the femur, tibia, and humerus, and in the area of the bone that has the fastest growth rate, they can occur in any bone. The most common symptom is pain, but swelling and limited movement can occur as the tumor grows.

Osteosarcoma is an orphan disease with approximately 1,200 new cases diagnosed in the United States each year. A similar incidence of the disease exists in Europe. According to the Children's Oncology Group (COG), the survival of children with osteosarcoma has remained at 60-65 percent since the mid-1980s. The standard treatment for osteosarcoma is tumor resection with combination chemotherapy before and after surgery.
NCCN publishes new informational resources on health and wellness for cancer survivors

NCCN publishes new informational resources on health and wellness for cancer survivors

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

Cholesterol in the plasma membrane is essential for SARS-CoV-2 entry and syncytia formation

MUSC cancer researcher named as a 2020 fellow of National Academy of Innovators

MUSC cancer researcher named as a 2020 fellow of National Academy of Innovators

Indiana University researchers report a specific type of childhood cancer

Indiana University researchers report a specific type of childhood cancer

WSU researchers use soy to improve post-operative treatment of bone cancer

WSU researchers use soy to improve post-operative treatment of bone cancer

Study may lead to new diagnostic and treatment strategies for fighting bone cancer

Study may lead to new diagnostic and treatment strategies for fighting bone cancer

MU offers an alternative to chemotherapy for treatment of cancer in animals and humans

MU offers an alternative to chemotherapy for treatment of cancer in animals and humans

Study shows fused lung cells are pervasive in severe COVID-19

Study shows fused lung cells are pervasive in severe COVID-19

Guidelines for making neutering decision

Guidelines for making neutering decision

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Breakthrough discovery could lead to ‘kinder’ treatments for childhood bone cancer

Water fluoridation not linked to increased risk of osteosarcoma, study shows

Water fluoridation not linked to increased risk of osteosarcoma, study shows

Study offers new insight into genetic alterations associated with osteosarcoma

Study offers new insight into genetic alterations associated with osteosarcoma

Uncovering the Achilles' heel of cancer cells to find effective cures

Uncovering the Achilles' heel of cancer cells to find effective cures

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Comprehensive tumor profiling reveals why osteosarcoma does not respond to immunotherapy

Why new cancer drugs take so long to reach the market

Why new cancer drugs take so long to reach the market

New approach can improve the activity of CAR-T cells against blood and solid cancers

New approach can improve the activity of CAR-T cells against blood and solid cancers

Cold plasma jets as promising tool for minimally invasive cancer therapy

Cold plasma jets as promising tool for minimally invasive cancer therapy

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Researchers identify targeted therapy for adolescent patients with neuroblastoma

Psoriasis drug could be repurposed to treat osteosarcoma

Psoriasis drug could be repurposed to treat osteosarcoma

Genetic similarities of deadly bone cancer between dogs and children revealed

Genetic similarities of deadly bone cancer between dogs and children revealed