Osteosarcoma News and Research

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Between two and three percent of all childhood cancers are osteosarcoma. Because osteosarcoma usually develops from osteoblasts, it most commonly affects children and young adults experiencing their adolescent growth spurt. Boys and girls have a similar incidence rate until later in their adolescence, when boys are more commonly affected. While most tumors occur in larger bones, such as the femur, tibia, and humerus, and in the area of the bone that has the fastest growth rate, they can occur in any bone. The most common symptom is pain, but swelling and limited movement can occur as the tumor grows.

Osteosarcoma is an orphan disease with approximately 1,200 new cases diagnosed in the United States each year. A similar incidence of the disease exists in Europe. According to the Children's Oncology Group (COG), the survival of children with osteosarcoma has remained at 60-65 percent since the mid-1980s. The standard treatment for osteosarcoma is tumor resection with combination chemotherapy before and after surgery.
New approach may improve translation of immunological research findings

New approach may improve translation of immunological research findings

Bone metastasis-targeting drug shows potential as new therapeutic strategy for osteosarcoma

Bone metastasis-targeting drug shows potential as new therapeutic strategy for osteosarcoma

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Existing drugs could help subgroup of patients with osteosarcoma, suggest scientists

Could a blood test predict how cancer spreads in children?

Could a blood test predict how cancer spreads in children?

Study finds steady decline in severe health problems for childhood cancer survivors

Study finds steady decline in severe health problems for childhood cancer survivors

Researchers identify how post-biotics lower blood glucose during obesity

Researchers identify how post-biotics lower blood glucose during obesity

Penn researchers discover antimicrobial that thwarts Zika viral entry into human cells

Penn researchers discover antimicrobial that thwarts Zika viral entry into human cells

Yoga during active treatment can provide QOL benefits for pediatric cancer patients and parents

Yoga during active treatment can provide QOL benefits for pediatric cancer patients and parents

New treatment prevents chemotherapy-induced hearing loss in children with cancer

New treatment prevents chemotherapy-induced hearing loss in children with cancer

Study finds lack of improvement in health status of childhood cancer survivors

Study finds lack of improvement in health status of childhood cancer survivors

Cancer cell's shape may offer clues for precise prognosis

Cancer cell's shape may offer clues for precise prognosis

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Novel microwave-induced photodynamic therapy could target deeply situated tumors

Researchers find oldest evidence of cancer in 1.7 million-year-old fossil

Researchers find oldest evidence of cancer in 1.7 million-year-old fossil

OVC research may help improve cancer treatment

OVC research may help improve cancer treatment

Researchers trace lineage of sarcoma back to pericyte

Researchers trace lineage of sarcoma back to pericyte

New collaborative research program connects canine and human cancers

New collaborative research program connects canine and human cancers

Veterinarian conducts clinical trials to improve cancer treatment for animals, humans

Veterinarian conducts clinical trials to improve cancer treatment for animals, humans

Existing immunotherapy drug pembrolizumab shows promise for specific sarcoma subtypes

Existing immunotherapy drug pembrolizumab shows promise for specific sarcoma subtypes

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Immunotherapy with experimental monoclonal antibody could reduce neuroblastoma tumors

Initiatives to improve adolescent, young adult cancer outcomes justified

Initiatives to improve adolescent, young adult cancer outcomes justified