Osteosarcoma News and Research

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Between two and three percent of all childhood cancers are osteosarcoma. Because osteosarcoma usually develops from osteoblasts, it most commonly affects children and young adults experiencing their adolescent growth spurt. Boys and girls have a similar incidence rate until later in their adolescence, when boys are more commonly affected. While most tumors occur in larger bones, such as the femur, tibia, and humerus, and in the area of the bone that has the fastest growth rate, they can occur in any bone. The most common symptom is pain, but swelling and limited movement can occur as the tumor grows.

Osteosarcoma is an orphan disease with approximately 1,200 new cases diagnosed in the United States each year. A similar incidence of the disease exists in Europe. According to the Children's Oncology Group (COG), the survival of children with osteosarcoma has remained at 60-65 percent since the mid-1980s. The standard treatment for osteosarcoma is tumor resection with combination chemotherapy before and after surgery.
CPRIT awards research and recruitment grants to improve cancer research

CPRIT awards research and recruitment grants to improve cancer research

Study details a new pathway for tumor formation

Study details a new pathway for tumor formation

New cancer drug enters phase I clinical trials in humans

New cancer drug enters phase I clinical trials in humans

Clinical study data of Advaxis' Lm-LLO immunotherapies to be presented at SITC Annual Meeting

Clinical study data of Advaxis' Lm-LLO immunotherapies to be presented at SITC Annual Meeting

Newly-identified cancer cell fingerprints in the blood could help diagnose childhood cancer

Newly-identified cancer cell fingerprints in the blood could help diagnose childhood cancer

Dominica Anderson named recipient of 2014 Julie and Ben Rogers Award for Excellence in Patient Care

Dominica Anderson named recipient of 2014 Julie and Ben Rogers Award for Excellence in Patient Care

Researchers study effect of alcohol on neural activity using fruit flies

Researchers study effect of alcohol on neural activity using fruit flies

Researchers investigate distribution of trace elements in tissue of bone tumours

Researchers investigate distribution of trace elements in tissue of bone tumours

Experimental antibody temporarily halts progression of neuroblastoma in children

Experimental antibody temporarily halts progression of neuroblastoma in children

Tumor-suppressing protein acts as dimmer switch to dial down gene expression

Tumor-suppressing protein acts as dimmer switch to dial down gene expression

Alteration in tumor suppressor gene TP53 plays key role early in development of bone cancer

Alteration in tumor suppressor gene TP53 plays key role early in development of bone cancer

ChromaTrap™ Chromatin Immunoprecipitation technology receives positive commentary in published paper

ChromaTrap™ Chromatin Immunoprecipitation technology receives positive commentary in published paper

First patient dosed in ADXS-HPV Phase 1/2 study for HPV-associated head and neck cancer

First patient dosed in ADXS-HPV Phase 1/2 study for HPV-associated head and neck cancer

Memorial Sloan-Kettering to use Sutro's cell-free protein synthesis technology to produce bispecific antibodies

Memorial Sloan-Kettering to use Sutro's cell-free protein synthesis technology to produce bispecific antibodies

Cancer survival rates still vary widely between European countries

Cancer survival rates still vary widely between European countries

Chinese and Western medicine combination could offer new hope for cancer treatments, therapies

Chinese and Western medicine combination could offer new hope for cancer treatments, therapies

Researchers find that Notch signaling elevated in tumors relative to normal bone

Researchers find that Notch signaling elevated in tumors relative to normal bone

Researchers identify mechanism behind pediatric solid tumors

Researchers identify mechanism behind pediatric solid tumors

Researchers to use $6.3M grant to develop novel therapeutic approaches for pediatric sarcomas

Researchers to use $6.3M grant to develop novel therapeutic approaches for pediatric sarcomas

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy

NUS researchers develop highly realistic 3-D tumor model to track progress of drug therapy