Otitis Media News and Research

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Acute otitis media (AOM) is a common childhood disease with important ramifications to the overall health of infants and young children. The peak incidence of AOM occurs at 6 to 18 months of age, but it can also occur in older children. Complications of AOM include persistent middle ear effusion, chronic otitis media, transient hearing loss, or speech delays.

Gene that makes some people susceptible to middle ear infections identified

Researchers at the University of Colorado Anschutz Medical Campus have found multiple genetic variants within the FUT2 gene that makes some people especially susceptible to middle ear infections.

25 Oct 2018

Ferring announces FDA approval of ZOMACTON for injection in four new pediatric indications

Ferring Pharmaceuticals Inc. today announced that the U.S. Food and Drug Administration has approved ZOMACTON for injection in four additional pediatric indications

20 Jul 2018

FDA provides guidance on Novus Therapeutics’ development path for OP-02 to treat otitis media

Novus Therapeutics, Inc., a specialty pharmaceutical company focused on developing products for patients with disorders of the ear, nose, and throat, announced receipt of final meeting minutes from the U.S. Food and Drug Administration following a Type C meeting held at the Company's request to discuss its OP-02 development program in otitis media.

19 Jun 2018

Tonsil and adenoid removal increases long-term risk of respiratory, allergic and infectious diseases

Tonsil and adenoid removal associated with long-term risks of respiratory, allergic and infectious diseases Removing tonsils and adenoids in childhood increases the long-term risk of respiratory, allergic and infectious diseases, according to researchers who have examined - for the first time - the long-term effects of the operations.

7 Jun 2018

Middle ear infection can lead to deadly neurological complications

While antibiotics have greatly reduced the dangers of ear infections, serious neurological complications, including hearing loss, facial paralysis, meningitis and brain abscess still occur, according to an article in the journal Current Neurology and Neuroscience Reports.

16 Apr 2018

NUS scientists develop novel handheld device for treatment of 'glue ear' in children

A team of researchers from the National University of Singapore has developed a novel handheld device, known as CLiKX, for the treatment of a condition called Otitis Media with Effusion, or 'glue ear', which is the leading cause of hearing loss and visits to the doctors among children worldwide.

24 May 2017

Shortened antimicrobial treatment inferior to standard regimen for middle ear infections, study finds

A five-day antimicrobial treatment regimen for middle ear infections in young children is inferior to the standard 10-day regimen, according to newly published research in The New England Journal of Medicine.

22 Dec 2016

Researchers discover gene region that raises risk of middle ear infections in children

Researchers have discovered a gene region that raises the risk a child will have a middle ear infection, known to doctors as acute otitis media (AOM)—and known to parents as one reason for a screaming, unhappy preschooler.

4 Oct 2016

Component in red wine and grapes can suppress inflammation linked to airway disease

A component of red wine and grapes can help control inflammation induced by a bacterial pathogen that is linked to upper respiratory tract inflammatory diseases such as asthma, chronic obstructive pulmonary diseases (COPD) and middle ear infection (otitis media), according to a study by researchers at Georgia State University.

28 Sep 2016

Single-dose of anibiotic gel could provide easy and safe treatment for common childhood illness

A single-application bioengineered gel, squirted in the ear canal, could deliver a full course of antibiotic therapy for middle ear infections, making treatment of this common childhood illness much easier and potentially safer, finds a preclinical study led by Boston Children's Hospital in collaboration with investigators at Boston Medical Center and Massachusetts Eye and Ear.

15 Sep 2016

New device uses shortwave infrared light to improve diagnosis of ear infections

A new device developed by researchers at MIT and a physician at Connecticut Children's Medical Center could greatly improve doctors' ability to accurately diagnose ear infections.

26 Aug 2016

Study estimates 30% of outpatient oral antibiotic prescription in the U.S as inappropriate

An estimated 30 percent of outpatient oral antibiotic prescriptions in the U.S. in 2010-2011 may have been inappropriate, findings that support the need for establishing a goal for outpatient antibiotic stewardship, according to a study appearing in the May 3 issue of JAMA.

4 May 2016

Software-based method could simplify diagnosis of ear infections

Researchers at Umea University in Sweden have developed a method that simplifies the diagnosis of ear infections (otitis media), something which annually affects half a billion children worldwide.

31 Mar 2016

Higher rates of breastfeeding, vaccination use cut ear infection in babies

In what would be considered good news for many parents a new study from The University of Texas Medical Branch at Galveston finds the rates of ear infections during a baby's first year have declined; the investigators suggested that higher rates of breastfeeding, use of vaccinations and lower rates of smoking may be the major contributors. The study was recently published in Pediatrics.

28 Mar 2016

Salvat, Lee's Pharmaceutical partner to market Duoxal ear drops in Greater China

Laboratorios SALVAT, S.A. and Lee's Pharmaceutical (HK) Limited, a wholly-owned subsidiary of Lee's Pharmaceutical Holdings Limited, jointly announced today the signing of an exclusive License and Supply Agreement for the marketing and distribution of Duoxal ear drops (patented combination solution of Ciprofloxacin and Fluocinolone Acetonide) in the People's Republic of China, Hong Kong S.A.R., Macau S.A.R., and Taiwan and an option to add Thailand to the contractual territory.

12 Jan 2016

Sound deprivation causes irreversible damage to the inner ear

Massachusetts Eye and Ear investigators have shown that sound deprivation in adult mice causes irreversible damage to the inner ear. The findings, published in PLOS ONE, suggest that chronic conductive hearing loss, such as that caused by recurrent ear infections, leads to permanent hearing impairment if it remains untreated.

19 Nov 2015

Researchers uncover groundbreaking evidence for developing vaccine to prevent middle ear infections

Researchers from Griffith University's Institute for Glycomics, together with the Nationwide Children's Hospital in Ohio, have uncovered groundbreaking evidence to help vaccine developers prevent middle ear infections.

30 Jul 2015

Simple procedure with nasal balloon can reduce impact of hearing loss in children

For children with a common middle-ear problem, a simple procedure with a nasal balloon can reduce the impact of hearing loss and avoid unnecessary and ineffective use of antibiotics, according to a new study led by researchers from the University of Southampton.

28 Jul 2015

Dr. Jian-Dong Li receives $1.6 million to develop novel therapeutic targets to treat middle-ear infections

Dr. Jian-Dong Li, a professor and director of the Institute for Biomedical Sciences at Georgia State University and a Georgia Research Alliance Eminent Scholar in Inflammation and Immunity, has received a five-year, $1.6 million federal grant to develop novel anti-inflammatory therapeutics against middle-ear infections.

2 Jul 2015

Rare genetic variants in A2ML1 gene responsible for chronic middle ear infections, say researchers

Many parents have heard the night-time cry of "my ear hurts." For some children, this might happen frequently beginning in infancy and even persist into adulthood. An international consortium led by those at Baylor College of Medicine may have taken the first step on the road to understanding why only some people get frequent painful or chronic middle ear infections. The culprit may be rare genetic variants in a gene called A2ML1.

30 Jun 2015