Oxycodone News and Research

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Experimental insomnia treatment may help prevent opioid relapse

A good night's sleep has many proven health benefits, and a new Scripps Research study suggests one more: preventing opioid relapse.

6 Sep 2023

Opioids linked to increased risk of death in older adults with dementia

The study population included everyone in Denmark aged 65 and older diagnosed with dementia between Jan. 1, 2008 and Dec. 31, 2018 (n=75,471), including both home-living and nursing home residents. Of that group, 42% (31,619) of those diagnosed with dementia redeemed a prescription for an opioid at a pharmacy.

18 Jul 2023

Breaking the myth: opioids provide no advantage for acute back pain, study finds

The first placebo-controlled trial of opioids in acute low back and neck pain.

3 Jul 2023

The DEA relaxed online prescribing rules during covid. Now it wants to rein them in.

Federal regulators want most patients to see a health care provider in person before receiving prescriptions for potentially addictive medicines through telehealth — something that hasn't been required in more than three years.

27 Jun 2023

New Jersey's Medicaid reforms spurred increases in buprenorphine prescriptions to combat opioid addiction

Reforms to New Jersey's Medicaid program successfully spurred ongoing increases in buprenorphine prescriptions for the treatment of opioid addiction, according to a Rutgers analysis.

19 May 2023

Ketogenic diet's surprising impact on opioid sensitivity and withdrawal

Research investigates the effects of a ketogenic diet (KD) on responses to oxycodone, a commonly prescribed opioid for pain management. The study found sex-biased effects of KD on oxycodone responses in mice, suggesting potential implications for clinical pain management and treatment of opioid use disorder.

10 May 2023

Researchers identify a potential safer route to pain relief

Strategies to treat pain without triggering dangerous side effects such as euphoria and addiction have proven elusive.

4 May 2023

Insomnia drug shows potential as an effective treatment for opioid use disorder

The insomnia drug suvorexant (Belsomra) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research.

27 Apr 2023

Pain, hope, and science collide as athletes turn to magic mushrooms

The boxer felt broken. Every day, he was waking up in pain. Some days, it was debilitating headaches. Other times, it was his back. Or his fists. His ribs. His nose. On top of that, he had mood swings. Depression. Anxiety.

24 Apr 2023

New biologic inactivates potent opioid and reverses overdose

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose.

18 Apr 2023

End of covid emergency will usher in changes across the US health system

The Biden administration's decision to end the covid-19 public health emergency in May will institute sweeping changes across the health care system that go far beyond many people having to pay more for covid tests.

22 Mar 2023

Maternal opioid treatment after delivery not associated with adverse infant outcomes

Infants born to mothers prescribed opioids after delivery, mostly after a cesarean, are at no greater risk of harm shortly after birth than infants of mothers not prescribed opioids, finds a large study from Canada published by The BMJ today.

16 Mar 2023

New approach to pain management can reduce opioid use after urethroplasty

For men undergoing surgery to repair scarring in the urethra (urethroplasty), a new approach to pain management can reduce the need for strong opioid drugs without compromising pain control, reports a study in Urology Practice, an Official Journal of the American Urological Association.

21 Feb 2023

Study: Nearly one in eight West Virginia infants had in-utero exposure to opioids, stimulants

Nearly one in eight infants born in West Virginia between 2020 and 2022 had in utero exposure to opioids, stimulants and/or cannabis, according to researchers at West Virginia University Health Sciences.

8 Feb 2023

Research provides a comprehensive structural framework to design safer pain-relieving drugs

In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides.

18 Jan 2023

NY docs are now required to prescribe naloxone to some patients on opioid painkillers

Without opioid painkillers to dull the ache in his knees and other joints, Arnold Wilson wouldn't be able to walk half a block. The 63-year-old former New York City nurse has crippling arthritis for which he takes OxyContin twice a day and oxycodone when he needs additional relief.

5 Jan 2023

Oxycodone News and Research

Experimental insomnia treatment may help prevent opioid relapse

Opioids linked to increased risk of death in older adults with dementia

Breaking the myth: opioids provide no advantage for acute back pain, study finds

The DEA relaxed online prescribing rules during covid. Now it wants to rein them in.

New Jersey's Medicaid reforms spurred increases in buprenorphine prescriptions to combat opioid addiction

Ketogenic diet's surprising impact on opioid sensitivity and withdrawal

Researchers identify a potential safer route to pain relief

Insomnia drug shows potential as an effective treatment for opioid use disorder

Pain, hope, and science collide as athletes turn to magic mushrooms

New biologic inactivates potent opioid and reverses overdose

End of covid emergency will usher in changes across the US health system

Maternal opioid treatment after delivery not associated with adverse infant outcomes

New approach to pain management can reduce opioid use after urethroplasty

Study: Nearly one in eight West Virginia infants had in-utero exposure to opioids, stimulants

Research provides a comprehensive structural framework to design safer pain-relieving drugs

NY docs are now required to prescribe naloxone to some patients on opioid painkillers

How Medicare Advantage plans dodged auditors and overcharged taxpayers by millions

New fentanyl vaccine could prevent deadly opioid from entering the brain

New long-term opioid use associated with a heightened risk of death, study finds

A California man’s ‘painful and terrifying’ road to a monkeypox diagnosis

Innovations in baculovirus–insect cell expression systems

Compound Management and its Crucial Role in Early Pharmaceutical Research

Natural products: the next frontier in drug discovery

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